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Ca2+ Influx

Regulation of Ca2+ influx in myeloid cells  Role of plasma membrane potential, inositol phosphates, cytosolic free [Ca2+], and filling state of intracellular Ca2+ stores

Regulation of Ca2+ influx in myeloid cells Role of plasma membrane potential, inositol phosphates, cytosolic free [Ca2+], and filling state of intracellular Ca2+ stores

... the Ca2+ elevations was due to Ca2+ influx through a pathway sensitive to the electrical driving force and to ...No Ca2+ influx could be observed after (a) plasma membrane ...

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Overexpression of the vaccinia virus A38L integral membrane protein promotes Ca2+ influx into infected cells.

Overexpression of the vaccinia virus A38L integral membrane protein promotes Ca2+ influx into infected cells.

... A38L-induced permeability of the plasma membrane is in- dependent of virus particle production. As vaccinia virus par- ticles have been shown to modify the plasma membrane cy- toskeleton (10) and IAP is known to interact ...

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TNFα induces Ca2+ influx to accelerate extrinsic apoptosis in hepatocellular carcinoma cells

TNFα induces Ca2+ influx to accelerate extrinsic apoptosis in hepatocellular carcinoma cells

... 2+ influx, TRPM7 activity, and activation of calpain signaling in normal hepatic cell ...2+ influx was signifi- cantly inhibited after TRPM7 knockdown, indicating that TNFα-mediated Ca ...

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Differential regulation of nimodipine-sensitive and -insensitive Ca2+ influx by the Na+/Ca2+ exchanger and mitochondria in the rat suprachiasmatic nucleus neurons

Differential regulation of nimodipine-sensitive and -insensitive Ca2+ influx by the Na+/Ca2+ exchanger and mitochondria in the rat suprachiasmatic nucleus neurons

... One of our major finding is the preferential uptake by mito- chondria of depolarization-evoked nimodipine-insensitive Ca 2+ influx. This is demonstrated by the observation that FCCP markedly increased the ...

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Differential Regulation of Two Ca2+ Influx Systems by Pheromone Signaling in Saccharomyces cerevisiae

Differential Regulation of Two Ca2+ Influx Systems by Pheromone Signaling in Saccharomyces cerevisiae

... that compose this ion transporter or channel. sponse: Our findings support a model where yeast cells Regulation of HACS activity: The studies of Iida and growing in complete or rich media primarily employ others ...

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Cry1Ac, a bacillus thuringiensis toxin, triggers extracellular Ca2+ influx and Ca2+ release from intracellular stores in Cf1 cells

Cry1Ac, a bacillus thuringiensis toxin, triggers extracellular Ca2+ influx and Ca2+ release from intracellular stores in Cf1 cells

... We demonstrated that active toxins triggered Ca2+ surges which were produced largely by the influx of extracellular Ca2+ through toxin-made membrane pores but also by a small component o[r] ...

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Control of Ca2+ Influx and Calmodulin Activation by SK Channels in Dendritic Spines

Control of Ca2+ Influx and Calmodulin Activation by SK Channels in Dendritic Spines

... Given the highly effective endogenous buffering of Ca 2+ , if SK-channels are to influence spine membrane potential and Ca 2+ influx, then they must be spatially coupled to a Ca 2+ source (Fig 4A). SK-channels ...

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Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model

Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model

... 2+ influx in PCs and reversed the ataxic ...2+ influx, improved ataxia-associated phenotypes in SCA28 mice when given either prior to or after symptom ...

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Reverse mode Na+/Ca2+ exchange mediated by STIM1 contributes to Ca2+ influx in airway smooth muscle following agonist stimulation

Reverse mode Na+/Ca2+ exchange mediated by STIM1 contributes to Ca2+ influx in airway smooth muscle following agonist stimulation

... homologues [2,3]. In addition, we have previously shown expression of a range of TRPC homologues in HBSMC [4]. Plasma membrane Na + /Ca 2+ exchange acting in reverse mode is well documented in cardiac muscle, but only ...

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Na+/Ca2+ exchange current in ventricular myocytes of fish heart: contribution to sarcolemmal Ca2+ influx

Na+/Ca2+ exchange current in ventricular myocytes of fish heart: contribution to sarcolemmal Ca2+ influx

... The sarcoplasmic reticulum of fish cardiac cells is relatively poorly developed and obviously a minor factor in contractile activation in most fish species (Santer, 1985; Driedzic and Gesser, 1988; Vornanen, 1989, 1996b; ...

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Virus-Induced Ca2+ Influx Extends Survival of West Nile Virus-Infected Cells

Virus-Induced Ca2+ Influx Extends Survival of West Nile Virus-Infected Cells

... ⴙ influx. This influx was observed with different strains of WNV and in different types of ...ⴙ influx observed in WNV-infected cells. Ca 2 ⴙ influx was not detected after infection with ...

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Inhibition of voltage dependent Ca2+influx by extracellular ATP in salivary cells of the leech Haementeria ghilianii

Inhibition of voltage dependent Ca2+influx by extracellular ATP in salivary cells of the leech Haementeria ghilianii

... We demonstrate that micromolar concentrations of external ATP, but not adenosine, reversibly and in a dose-dependent manner inhibit the influx of Ca2+ through voltage-activated Ca2+ chan[r] ...

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Post Moult Calcification in the Blue Crab (Callinectes Sapidus): Relationships between Apparent Net H+ Excretion, Calcium and Bicarbonate

Post Moult Calcification in the Blue Crab (Callinectes Sapidus): Relationships between Apparent Net H+ Excretion, Calcium and Bicarbonate

... In the high external [HC03~] experiments, an increase in the apparent net H + efflux was shown without any increase in the net Ca2+ influx; and finally, temporary inequalities of the var[r] ...

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“New Look” Opioids: Biased Ligands

“New Look” Opioids: Biased Ligands

... Opioids produce presynaptic and postsynaptic effects that decrease response to excitatory pain input.. They inhibit presynaptic Ca2+ influx, decreasing neurotransmitter release, and hype[r] ...

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Ca2+ versus Zn2+ transport in the gills of freshwater rainbow trout and the cost of adaptation to waterborne Zn2+

Ca2+ versus Zn2+ transport in the gills of freshwater rainbow trout and the cost of adaptation to waterborne Zn2+

... Once the Ca2+ influx is ‘corrected’ unidirectional Ca2+ influx and unidirectional Zn2+ influx by restoration of functional transport sites Jmax, the during a 1 month exposure of freshwat[r] ...

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Essential oil from Xylopia frutescens Aubl  reduces cytosolic calcium levels on guinea pig ileum: mechanism underlying its spasmolytic potential

Essential oil from Xylopia frutescens Aubl reduces cytosolic calcium levels on guinea pig ileum: mechanism underlying its spasmolytic potential

... Conclusion: Spasmolytic action mechanism of XF-EO on guinea pig ileum can involve histaminergic receptor antagonism and Ca2+ influx blockade, which results in [Ca2+]c reduction leading t[r] ...

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Dual Ca2+ requirement for optimal lipid peroxidation of low density lipoprotein by activated human monocytes

Dual Ca2+ requirement for optimal lipid peroxidation of low density lipoprotein by activated human monocytes

... of Ca2+ in U937 cell-mediated lipid peroxidation of ...of Ca2+ from cell culture medium by EGTA inhibited U937 cell-mediated peroxidation of LDL ...Therefore, Ca2+ influx and mobilization were ...

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Altered intracellular Ca2+ handling in heart failure

Altered intracellular Ca2+ handling in heart failure

... This Ca2+ influx triggers a large-scale Ca2+ release through the Ca2+ release channel of the sarcoplasmic reticulum SR, Nonstandard abbreviations used: ARVD/C2, arrhythmogenic right vent[r] ...

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Adaptive mechanisms of intracellular calcium homeostasis in mammalian hibernators

Adaptive mechanisms of intracellular calcium homeostasis in mammalian hibernators

... In heart cells, excitation–contraction E–C coupling is governed by a mechanism known as Ca2+-induced Ca2+ release Fabiato and Fabiato, 1975, by which Ca2+ influx through individual L-typ[r] ...

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Rotavirus Infection Induces an Increase in Intracellular Calcium Concentration in Human Intestinal Epithelial Cells: Role in Microvillar Actin Alteration

Rotavirus Infection Induces an Increase in Intracellular Calcium Concentration in Human Intestinal Epithelial Cells: Role in Microvillar Actin Alteration

... This contradiction could be explained by the existence of two types of cells at a late stage of infection: first, a pool of cells in which extracellular Ca2⫹ influx induces [Ca2⫹]i eleva[r] ...

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