Calcium-activated potassium channel
The intermediate conductance calcium activated potassium channel KCa3 1 contributes to atherogenesis in mice and humans
... intermediate-conductance calcium-activated potassium channel ...this channel inhibits VSMC and lymphocyte activation in rats and ...
14
The synthesis of ligands for the large conductance calcium activated potassium channel
... cochlea^®^. Calcium influx potentiates the release o f neurotransmitters, this influx is inhibited by the activation o f BK and therefore it back regulates neurotransmitter ...intracellular calcium, ...
191
Calcium activated potassium channel of the tobacco hornworm, Manduca sexta: molecular characterization and expression analysis
... ion channel gene expression and channel density in vivo at the level of identified neurons or muscles whose developmental fates and behavioral roles are known (Truman, 1992; Weeks et ...in calcium ...
13
Original Article Cardiac sodium/calcium exchanger preconditioning promotes anti-arrhythmic and cardioprotective effects through mitochondrial calcium-activated potassium channel
... KB-R7943 is a well-known inhibitor of the reverse-mode NCX in heart, it also produces non-specific effects in non-heart tissues, i.e., Sobolevsky and Khodorov reported that KB- R7943 blocked N-methyl-D-aspartate chan- ...
11
Different expression of β subunits of the KCa1 1 channel by invasive and non invasive human fibroblast like synoviocytes
... KCa: calcium- activated potassium channel; LCA: lithocholic acid; MMP: matrix metalloproteinase; mRNA: messenger RNA; N/A: not available; NSAID: non- steroidal anti-inflammatory drug; OA: ...
14
Hypoxic pulmonary vasoconstriction: role of voltage-gated potassium channels
... sarcolemmal potassium channel conductance and transmembrane potassium ...Intracellular potassium concentration (140 mmol/l) is greater than that of extracellular potassium (5 mmol/l), ...
9
Molecular heterogeneity of large-conductance calcium-activated potassium channels in canine intracardiac ganglia
... formed in the BKα N-terminus MSS background, our results present differ- ences with their observations in terms of calcium- and voltage-dependence, prob- ably due to the predominant expression of β4 in IC neurons. ...
8
Impact of aging on calcium influx and potassium channel characteristics of T lymphocytes
... cytosolic calcium concentration is ...intracellular calcium stores located in the endoplasmic reticulum release calcium into the ...the calcium release activated calcium (CRAC) ...
7
Dietary potassium regulates vascular calcification and arterial stiffness
... As potassium can be transported via 4 types of potassium channels (42), we determined the roles of these channels in mediating low-potassium-induced VSMC ...ATP-sensitive potassium channels (K ...
14
Original Article Contribution of calcium-activated chloride channel to elevated pulmonary artery pressure in pulmonary arterial hypertension induced by high pulmonary blood flow
... bath solution. For recording I CI , the extracellular bath solution contained 141 mM NaCl; 4.7 mM KCl; 1.8 mM CaCl 2 ; 1.2 mM MgCl 2 ; 10 mM N-2- hydroxyethylpiperazine-N’-2-ethanesulfonic acid (HEPES); and 10 mM glucose ...
9
Histone deacetylase inhibition by Entinostat for the prevention of electrical and structural remodeling in heart failure
... ion channel expression pattern and similarities in myocardial action potential [15], and has therefore been successfully used for electrophysiological studies ...
9
Calcium potassium cyclo triphosphate
... The calcium and potassium ions are situated between the phos- phate layers and are each coordinated by six terminal phos- phate O atoms ...The calcium ion has a slightly distorted octahedron and the ...
6
Deciphering the role of STIM1 in nervous system development
... that calcium influx via L-type VDCC is required for growth cone attraction in response to netrin-1 (Hong et ...VDCC-dependent calcium currents, which is blocked by the inhibition of L-type VDCC (Nishiyama ...
251
Voltage activated currents in hippocampal CA1 neurones
... As shown in Fig. 2.4, cadmium blocked most of the outward current, and the TTX insensitive inward current in these neurones. These effects are more clearly illustrated in Fig. 2.8. In Fig. 2.8A are shown currents ...
205
Oxygen induced constriction of rabbit ductus arteriosus occurs via inhibition of a 4 aminopyridine , voltage sensitive potassium channel
... O2-sensitive potassium channels in the fetal and adult pulmonary circulation which regulate vascular tone in response to changes in O2 ...4-aminopyridine-sensitive potassium channel, causing membrane ...
8
Negative Incremental Resistance Induced by Calcium in Asymmetric Nanopores
... mM potassium chloride and micromolar to millimolar calcium ...the calcium ions. We think that these calcium ions interact in a time-dependent way with the permanent charge of the pore, ...
5
Tumor necrosis factor α modulates sodium-activated potassium channel SLICK in rat dorsal horn neurons via p38 MAPK activation pathway
... were pulled using a horizontal pipette puller (Sutter Instru- ment Company, Novato, CA, USA) and fire polished to have a resistance of 6–10 MΩ. The repetitive discharge of each cell was measured by the injection of 2.5 × ...
7
CALCIUM CHANNEL CURRENTS IN CULTURED PARS INTERCEREBRALIS NEUROSECRETORY CELLS OF ADULT LOCUSTA MIGRATORIA
... cells. Calcium plays an important role in neural physiology: neurosecretion depends on calcium influx into the cells and calcium currents carry the rising phase of action potentials in different ...
6
An overview of the potassium channel family
... membrane segments, S1-S4, form a module that somehow controls the opening and closing of the pore (Figure 3). The first three of these segments are inferred to be helical along most of their lengths and located on the ...
5
Analytical models of calcium binding in a calcium channel
... There is more than one way to introduce the Fermi dis- tribution and none is as well determined as a full field theory model of an ion channel, using the Poisson-Fermi differential equation 15 or other field ...
12