calorie restriction
Calorie restriction inhibits ovarian follicle development and follicle loss through activating SIRT1 signaling in mice
... CR: calorie restriction; FOXO3a: forkhead box group O; HE: hematoxylin and eosin; NC: normal control; NRF1: nuclear respiratory factor 1; PAGE: polyacryl amide gel electrophoresis; PBS: phosphate buffer ...
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Metabolic Parameters in Obese Dogs Undergoing to the Diet with Calorie Restriction
... a calorie restriction of 25% of the normal calorie intake of each patient based on the reduction of 30% from the initial ...daily calorie intake in further 10% and reassessment of the ...
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Immune response after experimental allergic encephalomyelitis in rats subjected to calorie restriction
... among calorie restricted animals ...Severely calorie- restricted rats (n = 14) had daily access to 7 g of an unbal- anced AIN-93G diet enriched in proteins and low in fat and carbohydrates [13] and water ad ...
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The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse
... Calorie restriction (CR) delays the onset of age-related disease and extends lifespan in a number of ...protein restriction (PR) for 3 ...of restriction was related to circulating leptin, ...
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Effect of short and medium term calorie restriction on skeletal muscle protein synthesis and mitochondrial enzyme activities in rats
... reduction in protein intake did not affect leucine flux in nonobese males at rest. Skeletal muscle constitutes the largest single component of the body and serves as the major repository of protein (close to 50 percent ...
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Does eating less make you live longer and better? An update on calorie restriction
... Abstract: The complexity of aging is hard to be captured. However, apart from its tissue-specific features, a structural and functional progressive decline of the whole organism that leads to death, often preceded by a ...
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Epigenetic aging signatures in mice livers are slowed by dwarfism, calorie restriction and rapamycin treatment
... Results: We first examined whether mice and humans experience similar patterns of change in the methylome with age. We found moderate conservation of CpG sites for which methylation is altered with age, with both species ...
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Effects of aging and calorie restriction on the global gene expression profiles of mouse testis and ovary
... Aging is a complex biological phenomenon characterized by a gradual and progressive loss of function in diverse organs and tissues. Global gene expression profiling is beginning to provide molecular signatures of aging ...
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The effects of graded levels of calorie restriction: II. Impact of short term calorie and protein restriction on circulating hormone levels, glucose homeostasis and oxidative stress in male C57BL/6 mice
... overall restriction of calories (calorie restriction: CR) or the incidental reduction in macronutrients such as protein (protein restriction: PR) that mediate these effects is ...
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Distinct effects of calorie restriction on adipose tissue cytokine and angiogenesis profiles in obese and lean mice
... Accumulating evidence suggests an important role for low- grade inflammation and adipose tissue remodeling in the development of obesity. In the present study we investigated the adipose tissue cytokine and ...
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Calorie restriction regime enhances physical performance of trained athletes
... The CR reduced athletes ’ heart rates when performing the same exercise at the same duration and level of power (Table 6). Similarly, the energy expenditure re- quired for running at 50%Vmax, 60%Vmax, and 70%Vmax and for ...
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Calorie Restriction Mimetics: Upstream-Type Compounds for Modulating Glucose Metabolism
... Abstract: Calorie restriction (CR) has been shown to prolong the lifespan of humans, but enforcing long-term CR is difficult. Therefore, a compound that reproduces the effect of CR without CR is needed. In ...
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When less may be more: calorie restriction and response to cancer therapy
... Calorie restriction (CR) extends lifespan and has been shown to reduce age-related diseases including cancer, diabetes, and cardiovascular and neurodegenerative diseases in experimental ...
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Relationship between protein O linked glycosylation and insulin stimulated glucose transport in rat skeletal muscle following calorie restriction or exposure to O (2 acetamido 2 deoxy d glucopyranosylidene)amino N phenylcarbamate
... substrates. Calorie restriction (60% of ad libitum intake) for 20 days causes decreased UDP-N-acetylhexosamine levels and increased insulin-mediated glucose transport in rat skeletal ...the calorie ...
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Impaired glucose metabolism and altered gut microbiome despite calorie restriction of ob/ob mice
... During the course of the study, both WT and OB mice gradually gained body weight while feeding ad libitum on normal chow (Fig. 1a). OB mice gained significantly higher body weight over a 7-week period compared to WT mice ...
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Calorie Restriction the Fountain of Youth
... The calorie restriction (CR) is now the most widely recognized life span-extending intervention in all varie- ties of animals, including various mammalian ...
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Intermittent fasting combined with calorie restriction is effective for weight loss and cardio-protection in obese women
... combined with CR, to that of IF alone, and CR alone. An additional limitation of the study was that it did not carefully control for food intake by providing food-based meals to the intervention groups (i.e. dinner meal ...
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Timing of Calorie Restriction in Mice Impacts Host Metabolic Phenotype with Correlative Changes in Gut Microbiota
... 1 Calorie-restricted mice exhibited altered metabolic outcomes and reduced inflammatory markers regardless of feeding ...30% calorie restriction; CRD, dark-phase-fed with 30% calorie ...
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Calorie restriction and cancer prevention: a mechanistic perspective
... Leptin is a peptide hormone produced by white adi- pose tissue, and the leptin receptor is a member of the class I cytokine receptor family that signals through the Janus kinase and signal transducer activator of trans- ...
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Appetite and gut peptide responses to exercise and calorie restriction The effect of modest energy deficits
... Delta plasma acylated ghrelin concentrations in Con ▼, Ex-Def ● and Food-Def ○ presented for all participants a, after the removal of three outlying participants b and presenting the val[r] ...
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