cAMP–PKA signaling pathway
Activation of the cAMP/PKA signaling pathway is required for post ecdysial cell death in wing epidermal cells of Drosophila melanogaster
... understood pathway, it is likely that peptide hormones also regulate programmed cell death in Drosophila metamorphosis. At the last step of metamorphosis, newly emerged adults undergo extensive cell death. Many of ...
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Regulation of the Gα-cAMP/PKA signaling pathway in cellulose utilization of Chaetomium globosum
... protein signaling pathway was involved in the production of cellulase, the cellulose- utilizing ability and cellulase activity of the pG14 and pGP6 mutants and the wild-type strain were ...protein-mediated ...
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Original Article Aquaporins 1, 3 and 8 expression and cytokines in irritable bowel syndrome rats’ colon via cAMP-PKA pathway
... The cAMP-PKA pathway is a part of the recep- tor G protein and the cAMP-PKA signaling path- way, and it plays an important role in mediating cell responses to various stimuli ...
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N-Docosahexaenoylethanolamine ameliorates LPS-induced neuroinflammation via cAMP/PKA-dependent signaling
... the cAMP/PKA signaling pathway [12, 14] which is also an inhibitory target for lipopolysaccharide (LPS)-induced NF-κB activation leading to inflammation ...upregulating cAMP/PKA ...
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Dysfunctional Mitochondria Modulate cAMP-PKA Signaling and Filamentous and Invasive Growth of Saccharomyces cerevisiae
... conserved signaling pathways that mediate external information to the ...with signaling and thereby modulates the cellular response to environmental ...several signaling pathways, including the ...
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The Heterotrimeric G-Protein GanB(α)-SfaD(β)-GpgA(γ) Is a Carbon Source Sensor Involved in Early cAMP-Dependent Germination in Aspergillus nidulans
... the cAMP/PKA signaling pathway, evi- denced by accelerated trehalose breakdown ...the cAMP/PKA pathway through downregu- lation of GanB signaling at the onset of ...
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Original Article γ-aminobutyric acid inhibits the growth of cholangiocarcinoma via cAMP/PKA signal pathway
... Cholangiocarcinoma is one of the highly malig- nant gastrointestinal tumors and has poor prognosis. It is difficult to diagnose owing to its anatomic location, growth patterns and lacking of definite diagnostic criteria. ...
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Novel Mechanism Coupling Cyclic AMP-Protein Kinase A Signaling and Golgi Trafficking via Gyp1 Phosphorylation in Polarized Growth
... port pathway. Our findings also suggest that the role of the cAMP- PKA signaling pathway is broader than just regulating hyphal gene ...transport pathway from the ER to the PM, ...
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Identification and Functional Characterization of Rca1, a Transcription Factor Involved in both Antifungal Susceptibility and Host Response in Candida albicans
... (cAMP/PKA) signaling pathway and the transcription factor Efg1, but also probably through its interaction with a transcriptional repressor, most likely ...the cAMP/PKA ...
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cAMP-Epac Pathway Stimulation Modulate Connexin-43 and MicroRNA-21 Expression in Glioma Cells
... as cAMP and its related signaling components (Toll et ...in cAMP and its down-stream signaling pathway including PKA and Epac have demonstrated to affect connexin ...This ...
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Original Article Effects of electroacupuncture at Shenting and Baihui on cAMP-PKA-CREB signaling pathways in rats with cognitive dysfunction caused by cerebral ischemia reperfusion
... Cognitive impairment after strokes has been recorded in some ancient Chinese literatures. It has been divided into mental diseases in Tr- aditional Chinese Medicine, including demen- tia, melancholia, language disorder, ...
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Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction
... intracellular signaling pathways involving various molecules such as cAMP, protein kinase A, receptor tyro- sine kinases, and non-receptor tyrosine ...involving cAMP/PKA, receptor tyro- sine ...
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Tor and Cyclic AMP-Protein Kinase A: Two Parallel Pathways Regulating Expression of Genes Required for Cell Growth
... upon PKA catalytic ...on PKA components downstream of Ras and upstream of the Tpk catalytic ...crease cAMP levels in response to glucose, we can exclude models in which Tor signaling activates ...
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Original Article Nasal administration of muscone promotes cAMP-PKA-CREB signaling in rats with traumatic brain injury
... the PKA-CREB pathway, which stimulates transcription of related downstream genes, such as NGF and BDNF, playing impor- tant roles in promoting the survival and repair of nerve cells [8, 9, 12, 13, ...of ...
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Investigation Of The Spatiotemporal Dynamics Of Camp And Pka Signaling And The Role Of Hcn4 Subunits In Anxiety-Related Behavior And Memory
... intracellular signaling events and postsynaptic potentials. The second messenger, cAMP, has been studied as a critical regulator of synaptic adaptations for four decades; yet the precise mechanisms ...
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Protein Kinase A Contributes to the Negative Control of Snf1 Protein Kinase in Saccharomyces cerevisiae
... Snf1 pathway, we searched for mutations that, like snf1, suppress reg1 for the slow-growth ...known pathway components (SNF1, SNF4, and SAK1), we recovered “fast” mutations, designated fst1 and ...the ...
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Histamine 1 receptor-Gβγ-cAMP/PKA-CFTR pathway mediates the histamine-induced resetting of the suprachiasmatic circadian clock
... Ca 2+ release from ryanodine receptor (RyR)-mediated in- ternal stores and this is the molecular mechanism underlying the histamine-induced phase delay of circa- dian neural activity rhythm in the SCN [12]. In the ...
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Activating PRKACB somatic mutation in cortisol-producing adenomas
... holoenzyme formation. We used a cell-based bioluminescence resonance energy transfer (BRET) assay as described previously (10) based on transient coexpression of a luciferase-tagged R subunit (either RIα, RIβ, RIIα, or ...
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cAMP/PKA/CREB/GLT1 signaling involved in the antidepressant-like effects of phosphodiesterase 4D inhibitor (GEBR-7b) in rats
... of cAMP/ PKA/pCREB/GLT1 signaling under the chronic stress con- dition and improve depression-like behaviors of rats (The possible mechanism of GEBR-7b reversed CUS-induced depression-like behaviors ...
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α-Viniferin Improves Facial Hyperpigmentation via Accelerating Feedback Termination of cAMP/PKA-Signaled Phosphorylation Circuit in Facultative Melanogenesis
... from PKA holoenzyme or accelerate the reassociation between C-subunit and R-subunit to generate inactive holoenzyme, since it mimicked Rp-cAMPS in the modulation of CREB phosphorylation coupled with CRTC1 ...the ...
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