Cancer Progression
Upregulation of miR-572 transcriptionally suppresses SOCS1 and p21 and contributes to human ovarian cancer progression
... breast cancer, hepatocellular carcinoma, melanoma, or neuroendocrine tumor, suggesting SOCS1 may be a potential target for antitumor therapy [14, 15, ...tumor progression and prognosis in tongue squamous ...
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Hypoxia - an explanation of prostate cancer progression mechanisms
... in cancer progression and metastasis ...initiation, progression, tumor stemness and resistance to therapy ...tumor progression, metastasis and resistance to common ...
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Epigenetic regulation in cancer progression
... in cancer are generally thought to be brought about by alterations in DNA and histone modifications that lead to the silencing of tumour suppressor genes and the activation of oncogenic ...breast cancer and ...
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Role of Smac/DIABLO in cancer progression
... Recently, our group analyzed the participation of Smac/ DIABLO in cervical cancer patients. Surprisingly, we found that Smac/DIABLO expression did not correlate inversely with progression. As a matter of ...
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Platelets, coagulation and fibrinolysis in breast cancer progression
... breast cancer, inhibitors of coagulation such as low-molecular-weight heparin and warfarin have been studied in clinical trials [80-84] (Table ...breast cancer represented a minority in most ...breast ...
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Cancer-associated adipocytes: key players in breast cancer progression
... to cancer progression by fueling or signaling [61, 78, ...ovarian cancer and acute myeloid leukemia at the adipocyte-tumor cell margin, providing fatty acids for rapid tumor growth [62, ...breast ...
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Membrane potential and cancer progression
... promote cancer progression, it may serve as a potential marker for tumor detection and treatment, with prognostic ...monitor cancer progres- sion (Gupta et ...
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FGF23 promotes prostate cancer progression
... Prostate cancer is the most common cancer in US men and the second leading cause of cancer ...prostate cancer cell lines tested and is present at increased levels in prostate cancer ...
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Zinc finger proteins in cancer progression
... in cancer progression through regulating transcription of downstream genes, which are involved in proliferation, apoptosis, migration and ...different cancer types are regulated by ...
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THE EFFECT OF SYK ON BREAST CANCER PROGRESSION
... The tumour suppressor role of Syk came to light when Coopman et al. in their research observed that in group of well defined cell lines taken for study, the cell lines that were of low invasive nature expressed high ...
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Proteomics analysis of colon cancer progression
... There was a significant up-regulation of RNA metabo- lism and spliceosome-associated protein expression (p = 6.12e−15), cell cycle division proteins (cell division cycle 5-like protein, cell division cycle and apoptosis ...
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Abstract: Breast cancer is the most common cancer in women and distant site metastasis is the
... in cancer metastases and they are regulated by epigenetic mechanisms ...breast cancer tissues [98,102–104]. miR-9 promotes breast cancer progression through targeting CHD1, the ...
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<p>LncRNA LINC00520 Predicts Poor Prognosis and Promotes Progression of Lung Cancer by Inhibiting MiR-3175 Expression</p>
... lung cancer patients. The role of lncRNA LINC00520 in the progression of various cancers has been con fi rmed, but its function in lung cancer has not been researched so ...
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Original Article Downregulation of long noncoding RNA MALAT1 induces epithelial-to-mesenchymal transition via the PI3K-AKT pathway in breast cancer
... breast cancer cells in vitro and further indicated that lower MALAT1 expression was linked to metastasis in breast ...breast cancer by activating the PI3K-AKT path- ...and cancer progression. ...
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Original Article Bmi-1 regulates epithelial-to-mesenchymal transition to promote migration and invasion of breast cancer cells
... breast cancer cells that promotes EMT and cellular ...breast cancer, par- ticularly in advanced ...breast cancer cells concomitant with altered cytoskel- eton ...breast cancer with high ...
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ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer
... Inactivation or mutation of the VHL gene causes various tumors, including clear cell renal cell carcinoma (ccRCC). In the present study, we identified ZBRK1 as a novel VHL interacting protein by yeast two-hybrid ...
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Heme oxygenase-1: emerging target of cancer therapy
... influence cancer de- velopment through multiple ...pact cancer progression through modulating tumor ...tate cancer cell growth and ...of cancer cells to chemotherapy or irradiation and ...
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Expression and Significance of GRP78 and HER-2 in Colorectal Cancer
... In previous study, GRP78 expression was elevated gradually in human normal colorectal tissues, adenoma specimens and colorectal carcinoma specimens. In addition, we found that GRP78 is overexpressed in CRC patients but ...
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Cancer initiation and progression: an unsimplifiable complexity
... in progression or therapeutic response are seen in the same tumour type, and by the fact that cancer morphology does not always reveal a similar underlying ...that cancer does not conform to simple ...
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siAh in prostAte cAncer development And progression
... compounds, identified Menadione as a Siah2 inhibitor. Menadione treatment inhibited HIF levels in cultured cells, increased expression of direct Siah2 targets, and inhibited formation of melanoma xenografts [48]. Given ...
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