Cancer stem cells (CSCs) study
Conversion of Stem Cells to Cancer Stem Cells: Undercurrent of Cancer Initiation
... of stem cell research has attracted more scientists than ever to study the stem cell biology and the possibility of the generation of ...pluripotent stem cells (iPSCs) opens a new page ...
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Concise Review : Cancer Cells, Cancer Stem Cells, and Mesenchymal Stem Cells: Influence in Cancer Development
... ovarian cancer, the number of CSCs can be increased by MSCs iso- lated from human ovarian tumor ascites via BMP2 and BMP4 ...ovarian cancer cells with potential mediation in resist- ance to ...
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Cancer Stem Cells in Osteosarcoma
... A study assessing the feasibility of using MSC surface markers to enrich for CSCs in osteosarcoma was done by Adhikari et al (33), who convincingly showed that CD117 + /Stro-1 + double-positive cells were ...
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Cancer stem cells in the development of liver cancer
... liver cancer, their roles in liver CSCs are largely ...hepatic stem/progenitor cells, but a recent study suggested that HCV could replicate in human fetal hepatocytes ...validation ...
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Cancer stem cells in head and neck cancer
... high cells (,10%) that form a tumor can regenerate the tumor when transplanted in the side of immunosuppressed mice, whereas higher concentrations of CD44 low tumor cells are not able to reform a ...this ...
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Role of cancer stem cells in hepatocarcinogenesis
... normal stem cells (HPCs) and CSCs by micro- array analysis or next-generation sequencing may prove to be useful to identify the dysregulated oncogenes or tumor suppressors and signaling pathways that are ...
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A Review on the Biology of Cancer Stem Cells
... of cancer are surgery and ...to stem cells, and also they can avoid the chemicals designed for destroying them and produce enzymes to protect against radiation-induced ...conducted. Cells with ...
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Nanotechniques Inactivate Cancer Stem Cells
... human cells. The search for adequate and relevant experimental models to study and assess the antitumor activity of various therapeutic agents is in ...breast cancer of mice ...EC cells and ...
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LUNG CANCER STEM CELLS-AN UPDATE
... NSCLC cells were cisplatin-resistant and capable of spheroid body formation, in vivo tumor ...A study established a panel of lung cancer cell lines from primary tumors and characterized a small ...
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Cancer stem cells and targeting strategies
... a study that demonstrated the capacity of glioblastoma stem cells to efficiently activate the ATM serine/threonine kinase (ATM) and the DNA damage checkpoint protein kinase (Chk1) in response to ...
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Role of stem cells in cancer therapy and cancer stem cells: a review
... the cancer develop- ment through the cancer stem cells, with any possible therapies targeted against ...this study experienced the complete cytogenetic ...the stem cell homing ...
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Alcohol, stem cells and cancer
... sporadic cancer formation in humans ...to study cancer progression in mice, as well as xenografts of cancer cell lines into recipients that many scientists have been able to employ ...
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Cancer Stem Cells In Breast Cancer: A Review
... of stem cells from animals and humans: embryonic stem cells and non-embryonic somatic or adult stem ...adult stem cells in a living organism are to maintain and repair the ...
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Requirement of the transcription factor YB-1 for maintaining the stemness of cancer stem cells and reverting differentiated cancer cells into cancer stem cells
... in cancer stem cells have not been extensively ...previous study to be associated with stemness of melanoma stem cells [27], in the maintenance of stemness of cancer ...
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Multiple myeloma cancer stem cells
... in cancer is associated with increased stemness and poor clinical outcome [21, ...− cells exhibited significantly higher levels of ALDH activity than CD138 + plasma ...B cells isolated from the ...
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Encapsulated stem cells for cancer therapy
... therapeutic stem cells provides numerous advan- tages and helps overcome a number of caveats in the current cell based ...therapies. Stem cells have an incredible potential in developing novel ...
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Lgr4 in Breast Cancer Stem Cells
... Another study showed that RSPO-induced activation of LGR4 and LGR5 regulate both Wnt/β-catenin as well as Wnt/PCP pathways through Clathrin-dependent endocytosis (Glinka et ...
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Ovarian cancer: emerging concept on cancer stem cells
... another study describes that two mouse ovarian cancer cell lines such as MOVCAR7 and 4306 con- tain candidate cancer stem cells ...ovarian cancer cells have large SP, ...
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The role of P63 in cancer, stem cells and cancer stem cells
... – cancer stem cells; DBD – DNA-binding domain; EGR3 – early growth response 3; FRAS1 – Fraser syndrome 1; HNSCC – squamous cell carcinoma of the head and neck; HOXC4 – homeobox C4; ICAM – ...
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STAT3, stem cells, cancer stem cells and p63
... STAT3 can be activated and thereby contribute to CSCs properties by the BMX [43] and Ras homolog family member C [154] and it can be activated also epigenetically by the histone-lysine N-methyltransferase Enhancer of ...
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