cancer stem-like cell
Promotion of Cancer Stem-Like Cell Properties in Hepatitis C Virus-Infected Hepatocytes
... of cancer stem-like cell (CSC) markers, including high levels of the stem cell factor receptor ...with cell culture-grown HCV genotype ...
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CXCR2 is a novel cancer stem-like cell marker for triple-negative breast cancer
... Breast cancer is the leading cause of mortality from cancer in women worldwide, and cancer stem-like cell (CSC) is responsible for failure treatment of breast ...breast ...
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Cancer stem-like cell: a novel target for nasopharyngeal carcinoma therapy
... a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and ...as cell surface markers for some breast and prostate cancer stem cells ...NPC ...
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Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway
... Cancer stem cells are currently believed to be the root cause of cancer, which contribute to resistance to ther- apy, tumor recurrence, and distant ...the cancer stem cell ...
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Oxaliplatin-incorporated micelles eliminate both cancer stem-like and bulk cell populations in colorectal cancer
... Figure 5 OXA-loaded CSO-SA micelles enhance antitumor efficacy and reduce cancer stem-like cell enrichment in vivo. (A) reduced size of subcutaneous colon carcinoma tumors derived from ...
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Hydrodynamic shear stress promotes epithelial mesenchymal transition by downregulating ERK and GSK3β activities
... breast cancer cells derived from chemotherapy-treated patients (CT-PCs) into CT + shear stress (SS) displaying cancer stem-like cell (CSLC)/tumor-initiating cell (TIC) ...
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Canine mammary tumors contain cancer stem like cells and form spheroids with an embryonic stem cell signature
... tentative stem-like cells in the canine mam- mary tumor cell line ...This cell line is established from an atypical benign mixed mam- mary tumor, which has the property of forming ...
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Nestin suppression attenuates invasive potential of endometrial cancer cells by downregulating TGF-β signaling pathway
... a stem cell marker is expressed in several ...endometrial cancer. Compared to the immortalized endometrial epithelial cell line EM-E6/E7-TERT, endometrial cancer cell lines ...
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Vascularized Tissue-Engineered Model for Studying Drug Resistance in Neuroblastoma
... different cell types forming a vessel and remaining after drug treatment: HUVEC (positive for CD31; SOX2-, MYCN-), cancer stem-like cell (MYCN+/SOX2+), TEC (MYCN+/CD31+) and ...
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Natural and synthetic progestins enrich cancer stem cell-like cells in hormone-responsive human breast cancer cell populations in vitro
... breast cancer tumor growth and ...breast cancer cells in vitro. We found that treatment of T47-D breast cancer cells with Ps induced CD44 protein expression through a PR-mediated mechanism, and that ...
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A cancer-favoring oncolytic vaccinia virus shows enhanced suppression of stem-cell like colon cancer
... on cell surface marker expression using cell-separation methods, such as flow cytometry, magnetic sorting, or ...normal stem cells [36]; therefore, developing specific agents for targeting and ...
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Reduction of miR-29c enhances pancreatic cancer cell migration and stem cell–like phenotype
... the stem cell-like properties of a fraction of cells within the tumor ...the stem cell-like property of PANC ...PANC cell self- renewal ...
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Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy
... phenotype is also associated to chemoresistance. To this end, we treated Hela and T47D cells carrying NumbL shRNA (shNbL2 cells) or scramble (scr) to different doses of several chemotherapeutic drugs used in clinical ...
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Lung cancer stem cells and low-intensity laser irradiation: a potential future therapy?
... lung cancer associated with smoking are small cell lung cancer (SCLC) and non-small cell lung can- cer ...lung cancer. Novel therapies and treatments like LILI and PDT could im- ...
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Senescence-associated IL-6 and IL-8 cytokines induce a self- and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in the MCF-7 breast cancer cell line
... of stem-like cell properties, such as self-renewal and differentiation ...mesenchymal stem cells ...breast cancer hetero- geneity ...breast cancer cells is more related to this ...
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Cyclin D1 affects epithelial–mesenchymal transition in epithelial ovarian cancer stem cell-like cells
... epithelial cell adhesion junctions and tight junctions, and re-express or upregulate proteins originated from mesenchymal ...nonepithelial cell features, including loss of cell ...
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Cancer cell reprogramming: a promising therapy converting malignancy to benignity
... CSC: cancer stem cell; ESC: embryonic stem cell; iPSC: induced pluripotent stem cell; KLF4: Kruppel-like factor 4; Oct-3/4: Octamer-binding transcrip- tion factor ...
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MiR-744 increases tumorigenicity of pancreatic cancer by activating Wnt/β-catenin pathway
... pancreatic cancer progression, miR-744 was stably transduced into the MIA PaCa-2 and AsPC-1 pancreatic cancer cell lines via retroviral- and lentiviral-vector to generate MIA PaCa-2/miR-744 and ...
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Hepatitis C Virus-Induced Cancer Stem Cell-Like Signatures in Cell Culture and Murine Tumor Xenografts
... Our studies suggest a novel role of DCAMKL-1 in main- taining HCV RNA abundance. The basal expression level of DCAMKL-1 is found to be extremely low or absent in normal hepatocytes. However, active HCV replication, the ...
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Original Article Prognostic value of Thy1 in non-small cell lung cancer: a RNA-Seq transcriptome analysis
... regulate cell-matrix and cell-cell ...of cancer stem ...small cell lung cancer (NSCLC), we cultured the stem cell-like sphere 95D cell lines in ...
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