Cancer Subtypes
COMPUTATIONAL DRUG REPURPOSING FOR BREAST CANCER SUBTYPES
... ten subtypes of breast cancer, we aim to obtain a ranked list of drugs which would make suitable candidates for drug repurposing and drug repositioning for all ten breast cancer ...
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Breast cancer subtypes and survival in patients with brain metastases
... IHC subtypes in correlation with survival in 469 early stage breast cancer patients in the pre-trastuzumab era with a mini- mum of ...breast cancer subtypes predict the disease recurrence and ...
8
Prognostic parameters of luminal A and luminal B intrinsic breast cancer subtypes of Pakistani patients
... breast cancer subtypes which have exclusive prognosis [13, ...breast cancer is notably important in determining the thera- peutic interventions; however, the biological behavior of the molecular ...
6
Circular RNAs and their associations with breast cancer subtypes
... breast cancer samples, provided by The Cancer Genome Atlas (TCGA) ...breast cancer subtypes: triple negative (TN), estrogen receptor positive (ER+), and ErbB2 overexpressed–HER2 positive ...
13
Ki67 index in intrinsic breast cancer subtypes and its association with prognostic parameters
... breast cancer subtypes has made a paradigm shift in breast can- cer ...breast cancer management as per American Society of Clinical Oncology (ASCO) guidelines ...
5
2. STUDY OF METASTATIC CANCER OF BREAST WITH SPECIAL REFERENCE TO BREAST CANCER SUBTYPES
... Breast cancer is a major medical problem with significant public health and societal ramifications and is a leading cause of cancer death in ...five subtypes of breast cancer (luminal A, ...
9
Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.
... breast cancer based on polygenic risk scores (PRSs) could improve screening and pre- vention ...breast cancer in the top centile of the PRSs was ...breast cancer risk that may improve breast ...
14
Breast cancer subtypes, mouse models, and microarrays
... described above, much higher frequency in the two ER negative subtypes[3]. Mutations in p53 are also responsible for Li-Fraumeni syndrome, a hereditary disease predisposing patients to a spectrum of tumor types ...
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Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
... breast cancer PRS was also evaluated among 190,040 women of European ancestry from the UK Biobank cohort who had not had any cancer diagnosis or mastectomy prior to ...of cancer, death, or January ...
15
Pathway-based classification of cancer subtypes
... breast cancer metastasis data, the cyto- kine pathway leading edge genes included eight IL mem- bers and 5 tumor necrosis factor receptor superfamily (TNFRS) members which activate immune system ...rian ...
22
Independent prognostic impact of preoperative serum carcinoembryonic antigen and cancer antigen 15 3 levels for early breast cancer subtypes
... shown to be a significant prognostic factor for distant metastasis (p < 0.01), but not for locoregional events (p = 0.45) [26]. No significant association between metastatic sites and either elevated CEA or CA15-3 has ...
11
Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype.pdf
... breast cancer biological subtypes by immunohistochemis- ...breast cancer subtypes has been previously published (9, ...breast cancer is defined differently by the two ...
9
Analysis of PDLIM4 Expression in Different Subtypes of Breast Cancer
... definite cancer subtypes, significant role of this gene in malignant transformation of cells still remains ...breast cancer cells: to use expressor of PDLIM4 in cell lines, were this gene is ...
8
Improvement of cancer subtype prediction by incorporating transcriptome expression data and heterogeneous biological networks
... cer subtypes in BRCA gene/miRNA expression datasets by incorporating mRNA-TF-miRNA regulatory ...identified cancer subtypes based on various corresponding clinical data in breast cancer and ...
12
DNA methylation epigenotypes in breast cancer molecular subtypes
... tumor subtypes may represent transformation of stem ...breast cancer), which then progresses to differen- tiated cells with more luminal characteristics ...luminal subtypes, which would explain their ...
12
MiR 9 and miR 200 regulate PDGFRβ mediated endothelial differentiation of tumor cells in triple negative breast cancer
... breast cancer subtypes. In a cohort of 78 breast cancer tissues (set 1), we observed higher expression of miR-9 in TNBC than luminal and HER2+ subtypes, a finding that was further validated in ...
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Neoadjuvant therapy for early-stage breast cancer: the clinical utility of pertuzumab
... 5-year survival rates were achieved for patients treated with both neutralizing HER2 antibodies (ie, TP arm), the best overall outcomes were always attained by incorporating a chemotherapy regimen with the anti-HER2 ...
11
<p>Night-shift work and risk of breast cancer in Korean women</p>
... To the best of our knowledge, this is the fi rst study evaluating the association between NSW and breast cancer in Korean women and the third study conducted in the Asian population. Our fi ndings will provide ...
9
Single nucleotide polymorphisms and the etiology of basal-like and luminal A breast cancer : a pathway-based approach
... basal-like subtypes, which suggests that alterations to the sequence or structure of the genes have a similar effect on both breast cancer ...breast cancer in Tunisian and American women (20, ...both ...
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Radiomic signatures with contrast enhanced magnetic resonance imaging for the assessment of breast cancer receptor status and molecular subtypes: initial results
... breast cancer subtypes with imaging character- istics that included morphologic, radiomic, and dynamic enhancement features using a semi-automatic approach for lesion segmentation ...
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