Candidate genes: selection, diversity and functional variation
Multilocus Patterns of Nucleotide Diversity and Divergence Reveal Positive Selection at Candidate Genes Related to Cold Hardiness in Coastal Douglas Fir (Pseudotsuga menziesii var. menziesii)
... of genes underlying these traits, however, have remained elusive and thus so have the patterns of adaptive molecular diversity in forest tree ...of diversity and divergence for a set of 121 ...
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Haplotype Diversity in 11 Candidate Genes Across Four Populations
... identify genes controlling risk of oral clefts including sites in Maryland, Singapore, Taiwan, and ...of candidate genes using haplotype-based approaches in family-based tests of ...populations, ...
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Diversity across major and candidate genes in European local pig breeds
... genetic variation and population genetic structure based on a panel of candidate genes in a wide panel of European local pig ...segregating candidate SNPs associated with complex traits with ...
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DNA Sequence Variation and Selection of Tag Single-Nucleotide Polymorphisms at Candidate Genes for Drought-Stress Response in Pinus taeda L.
... nucleotide diversity and linkage disequilibrium and the selection of suitable polymorphisms for ...sequence variation data can be used to select candidate genes or amino acid sites that ...
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Impact of Natural Selection on Lignin and Cellulose Candidate Genes in a Natural Population of Eucalyptus urophylla
... 2.5. Determining the Demographic History of E. urophylla in Timor Island Using Microsatellites Data We used the Approximate Bayesian Computation (ABC) approach as implemented in DIYABC software [42], [43] to determine ...
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Nucleotide Diversity and Linkage Disequilibrium in Cold-Hardiness- and Wood Quality-Related Candidate Genes in Douglas Fir
... particular candidate gene or quantitative trait nucleotide ...system, selection, population size, struc- ture, and ...within genes was estimated in this study, but not presented and discussed here ...
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Analysis of functional candidate genes for meat quality and carcass traits in pigs
... genomic selection (Morozova and Marra, 2008; Ramos et ...emerging functional genomics technologies will allow the identification and mapping of functional allelic variants affecting meat quality and ...
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Selection and Validation of Reference Genes for Functional Studies in the Calliphoridae Family
... of candidate genes involved in feeding ...in functional studies, candidate genes for qPCR data normalization were selected and validated in three Calliphoridae (Diptera) species, ...
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Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes
... the variation in response to the chemotherapy of childhood ...the genes encoding ABC and SLC transporters: a large number of SNPs mapped to genes encoding ABCC4 and ABCC5, observations that confirm ...
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Using genetic variation in Aedes aegypti to identify candidate anti dengue virus genes
... genetic variation in vector competence within a single line of mosquitoes can be used to test for expression of gene candidates that vary with respect to viral ...intensive functional studies. It may also ...
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Trait variation and genetic diversity in a banana genomic selection training population
... Ortiz and Vuylsteke [ 43 ] that non-apical dominance genes were fixed in AA genotypes of Musa. GxE interaction The effects of cycle and field input management on the genotype and how the genotype inter- acted with ...
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Genetic diversity and population structure of genes encoding vaccine candidate antigens of Plasmodium vivax
... haplotype diversity compared to other geographic populations included in the final ...allelic diversity in this region is determined by complex demographic processes that include heterogeneity of ...
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Candidate genes and functional noncoding variants identified in a canine model of obsessive compulsive disorder
... Discussion Through a small GWAS (fewer than 90 cases and 70 controls) we identified OCD-associated loci, which, par- ticularly when analyzed together with regions of low variability, implicate specific cellular pathways ...
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An Exome-seq Based Tool for Mapping and Selection of Candidate Genes in Maize Deletion Mutants
... of genes in developmental and biochemical ...the functional genomics of kernel development, we developed a mapping and gene identification pipeline, bulked segregant exome sequencing (BSEx-seq), to map ...
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Variation in endoglin pathway genes is associated with preeclampsia: a case–control candidate gene association study
... control candidate gene association ...potentially functional SNPs in ENG, TGF β 1, TGF β R1, ALK1, and TGF β R2 were genotyped with iPLEX W and TaqMan W ...
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Dissecting the organ specificity of insecticide resistance candidate genes in Anopheles gambiae: known and novel candidate genes
... further candidate insecticide resist- ance genes from the direct comparisons between dissected body parts from the resistant and susceptible strain for fur- ther functional validation, we applied a ...
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Dissecting the organ specificity of insecticide resistance candidate genes in Anopheles gambiae : known and novel candidate genes
... further candidate insecticide resist- ance genes from the direct comparisons between dissected body parts from the resistant and susceptible strain for fur- ther functional validation, we applied a ...
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Diversity from genes to ecosystems : a unifying framework to study variation across biological metrics and scales
... species diversity (Agrawal, ...species–gene diversity correlations ...genetic diversity (reviewed by Vellend et ...species diversity is inconsistent across studies and even within ...gene ...
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Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing
... PD candidate genes, rather than discovering all putative PD genes present within our WES dataset, we set a con- servative selection criteria by only including frameshifts that caused an ...
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Identification of candidate MLO powdery mildew susceptibility genes in cultivated Solanaceae and functional characterization of tobacco NtMLO1
... Presence of the inserts was assessed by colony PCR, restriction enzyme digestion and sequencing using the universal M13 primer pair. Inserts were then trans- ferred by LR recombination into the binary plasmid vector ...
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