capsid protein
Modest truncation of the major capsid protein abrogates B19 parvovirus capsid formation.
... VP1 capsid protein is fused to the Flag peptide (10), was cleaved with BamHI to eliminate a region between two BamHI sites, after which each PCR-amplified fragment that had been digested with BamHI was ...
5
Oral Administration of Astrovirus Capsid Protein Is Sufficient To Induce Acute Diarrhea In Vivo
... 8), capsid-induced disease is acute, waning by 72 hpi, and is dose ...the capsid-induced clin- ical disease is expected, as progeny capsid particles are not pro- duced in the absence of productive ...
6
The Rubella Virus Capsid Protein Inhibits Mitochondrial Import
... the capsid protein, E2, and E1. The capsid protein is a multifunc- tional RNA-binding protein and is the focus of our ...the capsid protein is to package the viral genome ...
12
The Interaction between the Major Capsid Protein and the Smallest Capsid Protein of Human Cytomegalovirus Is Dependent on Two Linear Sequences in the Smallest Capsid Protein
... virion capsid of this virus is composed primarily of four viral proteins (5, 10, 12, 13, 16, 19, ...a protein with an approximate mass of 149 kDa, and the 150 hexons and 12 pentons of the mature ...
6
Feline Calicivirus Capsid Protein Expression and Capsid Assembly in Cultured Feline Cells
... structural protein (capsid protein) assembled as 90 homodimers in a T53 icosahedral symmetry (12, ...the capsid protein gene differs among the members of this ...from capsid ...
5
Protein Phosphatase 1α Interacts with Venezuelan Equine Encephalitis Virus Capsid Protein and Regulates Viral Replication through Modulation of Capsid Phosphorylation
... of capsid and PP1 ␣ was performed ...with capsid, their coimmunoprecipitation was ...TC-83. Protein lysates were collected at 24 hpi and immunoprecipitated with anti-PP1 ␣ or an antihemagglu- tinin ...
18
Short Self-Interacting N-Terminal Region of Rubella Virus Capsid Protein Is Essential for Cooperative Actions of Capsid and Nonstructural p150 Proteins
... (SPs), capsid, E2, and E1, which are integral components of the virion ...the capsid, E2, and E1 proteins by a host-cell signal peptidase in the lumen of the endoplasmic ...the capsid protein ...
12
C Terminus of Infectious Bursal Disease Virus Major Capsid Protein VP2 Is Involved in Definition of the T Number for Capsid Assembly
... IBDV capsid is formed by two major structural proteins, VP2 and VP3, which assemble to form a T ⴝ 13 markedly nonspherical ...during capsid assembly. We have computed three-dimensional maps of IBDV ...
14
The Apical Region of the Herpes Simplex Virus Major Capsid Protein Promotes Capsid Maturation
... herpesvirus capsid assembly and maturation, which includes analyses of baculovirus and cell-free systems (6–11), temperature-sensitive mutants (12, 13), and three-dimensional reconstructions from cryoelectron ...
16
A Virally Encoded Chaperone Specialized for Folding of the Major Capsid Protein of African Swine Fever Virus
... the protein was bound to CAP80 and raise the interest- ing possibility that CAP80 can actively induce the conforma- tional maturation of the capsid ...allows protein folding to be coordinated with ...
9
Interaction between Simian Virus 40 Major Capsid Protein VP1 and Cell Surface Ganglioside GM1 Triggers Vacuole Formation
... ABSTRACT Simian virus 40 (SV40), a polyomavirus that has served as an important model to understand many aspects of biol- ogy, induces dramatic cytoplasmic vacuolization late during productive infection of monkey host ...
13
Three-Dimensional Localization of the Smallest Capsid Protein in the Human Cytomegalovirus Capsid
... HCMV capsid to an effective resolution of 22 Å from 446 particles ...unlabeled capsid from 479 particles and scaled it to the same resolution ...unlabeled capsid, that we attributed to antibodies ...
6
Important roles of C terminal residues in degradation of capsid protein of classical swine fever virus
... C-EGFP protein expressed at a low level and decreased over time, we assume that C-EGFP protein might be degraded after ...on protein level of cleaved C-EGFP ...C protein at N-terminal, EGFP-C ...
10
The so far farthest reaches of the double jelly roll capsid protein fold
... The fact that viruses with different hosts share a common structural solution suggests that the architecture was established in the early stages of evolution, before the branches of the evolutionary tree diverged into ...
6
Packaging signals in single-stranded RNA viruses: nature’s alternative to a purely electrostatic assembly mechanism.
... virus capsid assembly, it overlooks the vital cooperative roles by which the genomic RNA facilitates efficient encapsidation in an environment in which capsid protein concentrations are much lower ...
11
The Cellular Chaperone Heat Shock Protein 90 Is Required for Foot-and-Mouth Disease Virus Capsid Precursor Processing and Assembly of Capsid Pentamers
... facilitates protein folding and homeostasis (35), most likely reflecting a requirement for assisted protein folding as a result of the high rate of production of viral ...enterovirus capsid precursor ...
14
Adaptive Changes in Alphavirus mRNA Translation Allowed Colonization of Vertebrate Hosts
... the capsid protein, changes in the RNA se- quence that led to DLP appearance could have been constrained by the structural requirements of the capsid protein for virion stability and ...
11
Identification of immunodominant epitopes of e1 and nucleocapsid proteins of chikungunya virus with neutralizing capacity
... structural protein for vaccine purpose through generation of neutralizing antibodies that showed protection against CHIKV infection (Bao et ...E1 protein showed protection against alphavirus infection (Wust ...
8
Processing of the Semliki Forest virus structural polyprotein: role of the capsid protease.
... We showed directly that the protease activity responsible for the release of the capsid protein resides in the capsid itself: by progressive truncation of the cDNA used for the SP6 trans[r] ...
9
Structure of A197 from Sulfolobus Turreted Icosahedral Virus: a Crenarchaeal Viral Glycosyltransferase Exhibiting the GT-A Fold
... overall capsid architecture and the structure of its major capsid protein are very similar to those of the bacteriophage PRD1 and eukaryotic viruses Paramecium bursaria Chlorella virus 1 and ...
9