casein kinase I
The Casein Kinase I Protein Cck1 Regulates Multiple Signaling Pathways and Is Essential for Cell Integrity and Fungal Virulence in Cryptococcus neoformans
... Cck1 is required for fungal virulence. Fbp1 is essential for fungal virulence even though it is not required for the devel- opment of classical fungal virulence factors, including the pro- duction of melanin and capsule, ...
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Negative Regulation of Haa1 by Casein Kinase I protein Hrr25 in Saccharomyces cerevisiae
... cerevisiae, casein kinase I has four isoforms, Yeast Casein Kinase 1(Yck1), Yck2, Yck3 and Hrr25, that are involved in regulation of DNA repair, morphogenesis, cell growth, glucose ...
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Casein kinase I epsilon somatic mutations found in breast cancer cause overgrowth in Drosophila
... ABSTRACT We are using a candidate gene approach to identify genes contributing to cancer through somatic mutation. Somatic mutations were found in breast cancer samples in the human casein kinase I ...
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Phosphorylation of varicella-zoster virus glycoprotein gpI by mammalian casein kinase II and casein kinase I.
... Lanes: 1, 4, and 7, immunoprecipitates added to protein kinase assays with no exogenous source of phosphotransferase activity; 2, 5, and 8, immunoprecipitates added to kinase assays with[r] ...
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Involvement of Hepatitis C Virus NS5A Hyperphosphorylation Mediated by Casein Kinase I-α in Infectious Virus Production
... Our intra- and extracellular infectivity assays following CKI- ␣ depletion suggested that CKI-␣ primarily targets virion assembly in the HCV life cycle (Fig. 4D to F), although a slight but nonneg- ligible negative ...
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Phosphorylation of the MAPKKK Regulator Ste50p in Saccharomyces cerevisiae: a Casein Kinase I Phosphorylation Site Is Required for Proper Mating Function
... vitro kinase assay established that Thr42 of Ste50p was phosphorylated by ...relevant kinase, further analysis using other purified CKI isomers (Yck2p and Hrr25p) indicated that all yeast CKI isomers tested ...
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Mechanism and evolution of cytosolic Hedgehog signal transduction
... protein kinase A (PKA), casein kinase I (CKI) and glycogen synthase kinase 3 (GSK3), targeting the proteins for proteasome- dependent processing (Bhatia et ...
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The emerging roles of phosphatases in Hedgehog pathway
... protein kinase (PKA) and casein kinase I (CK1) [22–24] is the most critical step to inhibit Smo ubiquitination and its subse- quent endocytosis and degradation [25, 26], resulting in Smo cell ...
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The human DNA-activated protein kinase phosphorylates simian virus 40 T antigen at amino- and carboxy-terminal sites.
... Serines 123 and 679 can be phosphorylated in vitro by casein kinase I 14; however, kinases that phosphorylaLe other sites have not been identified, and the gene 5131 Downloaded from http[r] ...
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T-antigen kinase inhibits simian virus 40 DNA replication by phosphorylation of intact T antigen on serines 120 and 123.
... Traugh, and Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest DISCUSSION This study demonstrates that the ability of T-antigen kinase, an isoform of casein kinase I, to in[r] ...
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Regulation of the Drosophila melanogaster Protein, Enhancer of Rudimentary, by Casein Kinase II
... The Drosophila melanogaster gene enhancer of rudimentary , e(r), encodes a conserved protein, ER. Most ER homologs share two casein kinase II (CKII) target sites. In D. melanogaster , these sites are T18 ...
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Incorporation of extracellular polysaccharide produced by Xanthomonas campestris into milk powders : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in Food Technology at Massey University
... For commercial production of dairy powders containing UF ferment EPS it is vital that either the xanthan or casein micelle structure be altered to prevent casein flocculation.. If this i[r] ...
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Casein Kinase 1α Mediates the Degradation of Receptors for Type I and Type II Interferons Caused by Hemagglutinin of Influenza A Virus
... It has been reported that Kaposi’s sarcoma-associated herpesvirus (KSHV) down- regulates IFN- ␥ receptor 1 via viral K3 and K5 proteins. It was shown that the overex- FIG 9 CK1 ␣ inhibition increases type I IFN ...
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The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix.
... serine kinase exhibits decreased levels of MA serine ...serine/threonine kinase, the binding of which also de- pends on an arginine residue at position 106 of HIV-1 Nef ...
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Incorporation of extracellular polysaccharide produced by Xanthomonas campestris into milk powders : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in Food Technology at Massey University
... For commercial production of dairy powders containing UF ferment EPS it is vital that either the xanthan or casein micelle structure be altered to prevent casein flocculation.. If this i[r] ...
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Ciclopirox activates ATR-Chk1 signaling pathway leading to Cdc25A protein degradation
... active kinase, whose activity is primarily determined by the cellular protein level [46], we reasoned that CPX-induced phosphorylation of Cdc25A (S82) is through upregulating protein expression of ...
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LncRNAs and immunity: watchdogs for host pathogen interactions
... NRON is non-coding repressor of NFAT (Nuclear Factor of Activated T cells), first identified during a short hairpin RNA (shRNA) library screening against 512 evolutionarily conserved lncRNAs [32]. NFAT is a highly ...
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The Phosphoprotein of Rabies Virus Is Phosphorylated by a Unique Cellular Protein Kinase and Specific Isomers of Protein Kinase C
... example, casein kinase II (CKII) and an L-protein- associated protein kinase (LAK) are specifically used for phos- phorylation of the P protein of vesicular stomatitis virus (VSV) (2, 3), whereas the ...
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Casein kinase 1α: biological mechanisms and theranostic potential
... phosphatidylinositol-3 kinase; PLK1: polo-like kinase 1; PRMT1: Protein arginine methyltransferase 1; PS1/2: Presenilin 1/2; PTEN: Phosphatase and tensin homolog deleted on chromosome ten; RAPGEF2: Rap ...
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Mechanisms of GPCR signal regulation in fission yeast
... Davis, “Akr1p and the type I casein kinases act prior to the ubiquitination step of yeast endocytosis: Akr1p is required for kinase localization to the plasma membrane,” Mol Cell Biol, v[r] ...
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