Cathepsin B
Cathepsin B Cysteine Proteinase is Essential for the Development and Pathogenesis of the Plant Parasitic Nematode Radopholus similis
... are cathepsin L(EC 3.4.22.15) and cathepsin B (EC ...sent, cathepsin L gene (cl) has drawn much attention and research efforts in plant parasitic nematodes, such as ...(ACH56225). ...
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Interaction of the Hepatitis B Spliced Protein with Cathepsin B Promotes Hepatoma Cell Migration and Invasion
... Hepatitis B spliced protein (HBSP) is involved in the pathogenicity and/or persistence of hepatitis B virus (HBV). Chronic HBV infection is one of the most important risk factors for the development of ...
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Determination of the concentration of cathepsin B by SPRI biosensor in children with appendicitis, and its correlation with proteasomes
... Conclusions. Cathepsin B concentration may reflect the metabolic response to acute state of inflamma- tion, surgical intervention in the abdominal cavity and the process of gradual ebbing of the ...
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Inhibitors of prostaglandin synthesis or cathepsin B prevent muscle wasting due to sepsis in the rat
... Cathepsin B activity was selectively elevated early in the course of ...a cathepsin B inhibitor, and indomethacin, a prostaglandin synthesis inhibitor, prevented muscle atrophy and impaired ...
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Elucidating the role of cathepsin B in the lifecycle of influenza A virus
... Influenza virus type A (IVA) is the etiologic agent responsible for the febrile respiratory illness referred to as the flu. Seasonal and occasionally pandemic IVA-associated illness is a significant cause of morbidity ...
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Decreased expression of APAF-1 and increased expression of cathepsin B in invasive pituitary adenoma
... and cathepsin B, alongside other important apoptotic molecules and in correlation with well-established markers of tumor status, such as Ki-67 and p53, may repre- sent a valuable panel for assessing PA ...
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Original Article Expression of cathepsin B in human hepatocellular carcinoma and its prognostic significance
... known, cathepsin B belongs to a class of cysteine that participates in numerous physio- logical and pathological ...of cathepsin B was found in brain tumors, espe- cially high-grade gliomas, ...
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Identification and characterization of Clonorchis sinensis cathepsin B proteases in the pathogenesis of clonorchiasis
... by cathepsin B specific inhibitors or cysteine protease specific inhibitors, while serine pro- tease specific inhibitors and trypsin specific inhibitor showed only a weak inhibition ...typical ...
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Molecular and Biochemical Characterization of a Cathepsin B-Like Protease Family Unique to Trypanosoma congolense
... congolense cathepsin B (with the “c” preceding the number referring to the active-site Cys), and the putative cathepsin B-like proteases with a serine instead of a cysteine in the catalytic ...
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Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis
... lysosomal, cathepsin B–dependent (Ctsb-dependent) pathway of apoptosis has been described, the contribution of this pathway to tissue damage remains ...
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Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis
... This cathepsin B hypothesis is based on the observations that CTSB can activate trypsinogen in vitro (9), that CTSB is redistributed to a zymogen-granule–enriched subcellular compartment (10), and that ...
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Nitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activity
... the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel ...Zidanik B, Golouh R, Lah T. Cathepsin B immunohistochemical staining in ...
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Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid- derived suppressor cells
... of cathepsin B and cathepsin D was required to significantly decrease LCL521-induced cell ...activate cathepsin B and cathepsin D, resulting in interrupted autophagy and ER ...
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Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasion
... decreases cathepsin B localization to caveolae in parallel with decreases in ECM degradation and cell invasion ...co-express cathepsin B and caveolin-1, we determined that degradation of type ...
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Cathepsin B trafficking in thyroid carcinoma cells
... Cathepsin B cDNA was derived from FRTL-5 cells, a Fisher rat thyroid cell line, as described previously ...the cathepsin B ...of cathepsin B into the pEGFP-N1 vector after fusion ...
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Original Article Elevated plasma cathepsin B and cystatin C levels in chronic obstructive pulmonary disease
... for neutrophil count, the CRP test, and quantitative protein analysis for cathepsin B and cystatin C. After adding the blood, the tubes were slightly mixed to prevent coagulation and hemolysis. Tubes ...
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Original Article Expression status of cathepsin B may as a prognostic marker for human gastric carcinoma
... Abstract: Cathepsin B (CTSB) is reported up-regulated in various tumors. However, data on its expression pattern and clinical relevance in gastric carcinoma are unknown. The aim of this study is to ...
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Split top: a maternal cathepsin B that regulates dorsoventral patterning and morphogenesis
... Convergence and extension are altered in split top mutants split top mutant embryos displayed altered overall morphology suggestive of defects in convergence and extension. Therefore, convergence and extension were ...
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Cathepsin B: a potential prognostic marker for inflammatory breast cancer
... CTSB B and cav-1 was scored accord- ing to both the intensity of staining and the proportion of positive staining carcinoma cells within the entire slide: “0”, no immunostaining was observed within carci- noma ...
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Cysteine Proteases and Cell Differentiation: Excystment of the Ciliated Protist Sterkiella histriomuscorum
... for cathepsin B, 349 sequences for cathepsin-L like proteins, and 79 sequences for ...package. Cathepsin B and cathepsin L-like sequence data sets were disjoined in order to ...
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