Cationic Liposome
Growth inhibition of combined treatment of cationic liposome/p53 complexes and cisplatin on human carcinoma cells
... Dimethyldioctadecyl ammonium bromide (DDAB), polyethylenimine (PEI 0.8KDa, branched), egg phosphatidylcho- line, and α-tocopherol polyethylene glycol 1000 succinate were purchased from Sigma-Aldrich (St. Louis, MO). ...
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Anticancer activity of the intraperitoneal-delivered DFP-10825, the cationic liposome-conjugated RNAi molecule targeting thymidylate synthase, on peritoneal disseminated ovarian cancer xenograft model
... shRNA/cationic liposome complex (TS shRNA-lipoplex, DFP-10825, Figure 1), TS shRNA and cationic liposome were mixed at a molar ratio of 2,000/1 (lipid:shRNA = 2,000:1), and the mixture was ...
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Potent Adjuvant Activity of Cationic Liposome-DNA Complexes for Genital Herpes Vaccines
... Development of a herpes simplex virus (HSV) vaccine is a priority because these infections are common. It appears that potent adjuvants will be required to augment the immune response to subunit HSV vaccines. Therefore, ...
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Preclinical studies for a cationic liposome formulation containing Il-2 Intended for the treatment of Human Tumors
... The IL-2 receptor (IL-2R) has been found to be express in a variety of epithelial cancer cells. Even though this receptor has been well characterized to activate lymphoid cells, its function on epithelial cells is mostly ...
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AlPcS<sub>4</sub>-PDT for gastric cancer therapy using gold nanorod, cationic liposome, and Pluronic<sup>®</sup> F127 nanomicellar drug carriers
... contribution by AuNR, Clip, and F127 carriers themselves on SGC-7901 gastric cancer cells with or without laser irra- diation, CCK-8 cell viability analysis was performed. As[r] ...
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Preparation Procedure of Liposome Absorbed Substrate and Tip Shape Correction of Diameters of Liposome Measured by AFM
... anionic liposome with lipid composition of DSPC and DSPG besides ones of the referred literature [2-5], whereas Neil ...studied cationic liposome by AFM. The anionic liposome suspension was ...
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pH-Sensitive carboxymethyl chitosan-modified cationic liposomes for sorafenib and siRNA co-delivery
... In this work, cationic liposome co-delivering Sf and siRNA (SiSf-CL) was developed. Then pH-sensitive CMCS was coated onto the positively charged complex at physiological pH via electrostatic interaction to ...
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LIPOSOME: A POWERFUL APPROACH FOR VESICULAR DRUG DELIVERY SYSTEM
... to cationic liposome plasmid DNA complexes results in an approximately fivefold increase in chloramphenicol acyl transferase activity detected in FAO hepatoma and 3T3-F442A adipocyte cells in vitro and up ...
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Effect of inserted spacer in hepatic cell-penetrating multifunctional peptide component on the DNA intracellular delivery of quaternary complexes based on modular design
... a cationic liposome, multifunctional peptide, and DNa at optimized ratios; hlPD: h represents hyaluronic acid, l represents cationic liposome that was composed of DOTaP/DOPe at a 1:1 weight ...
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Correction of renal tubular acidosis in carbonic anhydrase II deficient mice with gene therapy
... that cationic liposomes are ef- fective for gene transfer in the kidney ...(8–10). Cationic lipo- somes, composed of a cationic lipid and a neutral lipid, have been used as vehicles for gene transfer ...
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Attachment of class B CpG ODN onto DOTAP/DC chol liposome in nasal vaccine formulations augments antigen specific immune responses in mice
... Background: To overcome infectious diseases, the development of mucosal vaccines would be an effective strat- egy, since mucosal surfaces are the entry site for most pathogens. In general, protein antigens show ...
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Catechin Liposome Gel Formulation
... This research is the continuation from the previous research [4]. Catechin liposomes were made in the previous research. The previous research results fulfilled the requirements and we continue the research by making ...
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Liposome: classification, preparation, and applications
... stealth liposome is a sphere-shaped vesicle with a membrane composed of phospholipid bilayer used to de- liver drugs or genetic material into a ...A liposome can be composed of naturally derived ...
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Cryogenic transmission electron microscopy of recombinant tuberculosis vaccine antigen with anionic liposomes reveals formation of flattened liposomes
... The samples were prepared and imaged individually. ID93 (0.5 mg/mL stock concentration in 20 mM Tris buffer, pH 8) was diluted 1:10 with dilution buffer (20 mM Tris, pH 8) or mixed 1:1 with the liposome sample ...
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Involvement of let-7 microRNA for the therapeutic effects of Rhenium-188-embedded liposomal nanoparticles on orthotopic human head and neck cancer model
... of upstream regulators analyzed by IPA also included chemical drugs or inhibitors, but they were not considered in this study (Supplementary Figure 4). Interestingly, let-7 was the only gene belonging to microRNA family ...
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3-8-2013 12:00 AM The Effect of Glycan Linked to Cationic Peanut Peroxidase on its Activity
... Concanavalin A (Con A) has an affinity to mannose. The presence of terminal galactose in the glycans of CPRx (Figure 3) is supported by Con-A affinity chromatography. The first three gel filtration fractions, pooled ...
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Effective transcutaneous immunization by antigen-loaded flexible liposome in vivo
... OVA-loaded liposome dispersions after the Sephadex G-100 minicolumn centrifugation was transferred into a large tube containing 30 mL phosphate buffer (pH ...intact liposome dispersions ...
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Liposomes as nanomedical devices
... Since the overall positive charge of CLPs enhances the transfection of anionic animal target cells, liposome/DNA complexes are commonly used for delivering genes. However, preclinical and clinical results ...
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Synthesis and Characterization of Some Capsaicin Derivatives and Study their Pharmacological Hydrolysis
... using cationic polymerization were carried out to the synthesis of drug-spacer polymer to obtain more able as hydrolysis proceeded and more convenient for hydrolysis of attachment of the appropriate pendant drugs, ...
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Antibacterial and Anti-Fungal Activity of Copper and Nickel Nanoparticles Stabilized by Cationic Thiol Polyurethane Surfactants
... synthesized cationic Thiol polyurethane surfactants and their nanoparticles were tested against different strain of bacteria using inhibition zone diameters and showed good antimicrobial activities against the ...
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