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CCAAT/enhancer-binding protein-α

Protein-x of hepatitis B virus in interaction with CCAAT/enhancer-binding protein α (C/EBPα) - an in silico analysis approach

Protein-x of hepatitis B virus in interaction with CCAAT/enhancer-binding protein α (C/EBPα) - an in silico analysis approach

... and protein-x, compara- tive models were not ...initio protein folding and protein structure prediction. Protein-x is a relatively small protein, therefore prediction of the tertiary ...

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Oval Cells: Potential Role in Liver Regeneration

Oval Cells: Potential Role in Liver Regeneration

... morphogenetic protein 4 (BMP4), a member of the transforming growth factor super-family has been shown to in- duce rat hepatic progenitor cell differentiation towards the hepat- ocyte lineage in vitro as ...

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Myostatin gene promoter: structure, conservation and importance as a target for muscle modulation

Myostatin gene promoter: structure, conservation and importance as a target for muscle modulation

... Activator protein 1; ARE: Androgen receptor element; C/EBP α : CCAAT/enhancer-binding protein- α ; ChoRE: Carbohydrate responsive element; ChREBP: Carbohydrate responsive ...

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Genomic effects of the vitamin D receptor: Potentially the link between vitamin D, immune cells, and multiple sclerosis

Genomic effects of the vitamin D receptor: Potentially the link between vitamin D, immune cells, and multiple sclerosis

... the enhancer activity and the gene expression of the LD region (increasing the expression of TSFM/TSPAN31, reducing the expression of CYP27B1/METT21B/AVIL) in a allele-dependent and orientation-dependent way, by ...

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Tissue source determines the differentiation potentials of mesenchymal stem cells: a comparative study of human mesenchymal stem cells from bone marrow and adipose tissue

Tissue source determines the differentiation potentials of mesenchymal stem cells: a comparative study of human mesenchymal stem cells from bone marrow and adipose tissue

... AIM: Adipogenic induction medium; ALP: Alkaline phosphatase; AP2: Adipocyte protein 2; ATSC: Adipose tissue-derived MSC; BMSC: Bone marrow-derived MSC; CEBP α : CCAAT/enhancer-binding pr[r] ...

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Genetic Markers of Graves’ Disease: A Historical View and Up-date

British Journal of Medicine & Medical Research

... C/EBP α - CCAAT/enhancer-binding protein alpha; CTLA-4-cytotoxic T-lymphocyte-associated protein 4; DZ -dizygotic;FCRL3-Fc receptor-like protein 3; flCTLA-4- full-length ...

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CCAAT/enhancer binding protein β promotes receptor activator of nuclear factor kappa B ligand (RANKL) expression and osteoclast formation in the synovium in rheumatoid arthritis

CCAAT/enhancer binding protein β promotes receptor activator of nuclear factor kappa B ligand (RANKL) expression and osteoclast formation in the synovium in rheumatoid arthritis

... Cartilage degeneration and bone destruction are the main features of rheumatoid arthritis (RA) [1]. Inflammation pathways are involved in the catabolic processes of articu- lar cartilage and bone degeneration in RA. ...

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Detrimental role for CCAAT/enhancer binding protein δ in blood borne brain infection

Detrimental role for CCAAT/enhancer binding protein δ in blood borne brain infection

... inflammatory transcription factor, and was found to be essential in Fcγ receptor-mediated inflammatory cytokine and chemokine production. C/EBPδ deficient macro- phages failed to induce a full tumour-necrosis factor ...

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Biological roles of CCAAT/Enhancer-binding protein delta during inflammation

Biological roles of CCAAT/Enhancer-binding protein delta during inflammation

... receptor α and retinoic acid receptor, on the promoter regions of proinflammatory mediators activates CEBPD in an interleukin-1 receptor-associated kinase 1-dependent manner ...flammatory protein 2 and 1α ...

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TSG-6 secreted by human adipose tissue-derived mesenchymal stem cells ameliorates severe acute pancreatitis via ER stress downregulation in mice

TSG-6 secreted by human adipose tissue-derived mesenchymal stem cells ameliorates severe acute pancreatitis via ER stress downregulation in mice

... CHOP: CCAAT-enhancer-binding protein homologous protein; DMEM: Dulbecco ’ s modified Eagle ’ s medium; ELISA: Enzyme-linked immunosorbent assay; ER: Endoplasmic reticulum; FBS: Foetal ...

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The role of stromal cancer-associated fibroblasts in pancreatic cancer

The role of stromal cancer-associated fibroblasts in pancreatic cancer

... CHOP: CCAAT- enhancer-binding protein homologous protein; ECM: Extracellular matrix; EMT: Epithelial-mesenchymal transition; FAP: Fibroblast activation protein; FGF2: Fibroblast ...

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Combined platelet-rich plasma and lipofilling treatment provides great improvement in facial skin-induced lesion regeneration for scleroderma patients

Combined platelet-rich plasma and lipofilling treatment provides great improvement in facial skin-induced lesion regeneration for scleroderma patients

... These conditions promote a compensatory VEGF over- production by the endothelium. In healthy subjects the in- crease of VEGF is coupled with platelet-derived growth factor (PDGF), endothelin-1 (ET-1), transforming growth ...

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Transcription factors: Are they a real target for future therapeutic strategies?

Transcription factors: Are they a real target for future therapeutic strategies?

... suppress cytokine expression at the transcriptional level (83). In regard to therapy there are already specific PPAR-isoform inhibitors and activators available (84). 15-deoxy- Delta(12,14)-PGJ(2) (15d-PGJ(2)) and ...

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Endoplasmic reticulum stress and apoptosis

Endoplasmic reticulum stress and apoptosis

... Caspase-12 is located in the ER membrane and participates in apoptosis under ER stress. After the initiation of apoptotic pathways, procaspase-12 is cleaved and becomes activated by an unknown mechanism. In mice, ...

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Phyto-polyphenols as potential inhibitors of breast cancer metastasis

Phyto-polyphenols as potential inhibitors of breast cancer metastasis

... Migratory cancer cells show elevated expression MMPs, which are Calcium-dependent Zinc-containing endopeptidases capable of degrading extracellular matrix (ECM) proteins (Verma & Hansch 2007). There is a strong ...

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CCAAT/enhancer binding protein β is required for satellite cell self-renewal

CCAAT/enhancer binding protein β is required for satellite cell self-renewal

... factor CCAAT/enhancer binding protein beta (C/EBP β ) is expressed in Pax7 + satellite cells of healthy muscle and is downregulated during myoblast ...

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DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish

DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish

... Dnmt1 protein lacking its catalytic domain. DNMT1 protein is an important DNA methyltransferase to silence and regulate genes by methylation of DNA regions without changing the genomic DNA sequence ...

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Contaminating reactivity of a monoclonal CCAAT/Enhancer Binding Protein β antibody in differentiating myoblasts

Contaminating reactivity of a monoclonal CCAAT/Enhancer Binding Protein β antibody in differentiating myoblasts

... Objective: CCAAT/Enhancer Binding proteins (C/EBPs) are transcription factors involved in the regulation of a variety of cellular ...a protein other than ...

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A Protein Encoded by the Bovine Herpesvirus 1 Latency-Related Gene Interacts with Specific Cellular Regulatory Proteins, Including CCAAT Enhancer Binding Protein Alpha

A Protein Encoded by the Bovine Herpesvirus 1 Latency-Related Gene Interacts with Specific Cellular Regulatory Proteins, Including CCAAT Enhancer Binding Protein Alpha

... fusion protein. The LR fusion protein interacts with two proteins that can induce apoptosis (Bid and Cdc42) and with CCAAT enhancer binding protein alpha (C/EBP- ␣ ...fusion ...

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Complement component 3 (C3) expression in the hippocampus after excitotoxic injury: role of C/EBPβ

Complement component 3 (C3) expression in the hippocampus after excitotoxic injury: role of C/EBPβ

... C3 protein after KA injection was observed in both glial and neuronal cells as shown by double labeling with a C3-specific antibody and cell type-specific ...C3 protein inside the neurons and also in the ...

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