CCl4-induced hepatotoxicity
EFFECT OF COLEUS AROMATICUS LINN , ON CCL4 INDUCED HEPATOTOXICITY IN SWISS ALBINO RATS
... The present study has been carried out to evaluate the effect of coleus aromaticus leaves on CCl4 induced hepatotoxicity in swiss albino rats. Elevation of SGOT, SGPT, LDH, GGT and decline in NADH- ...
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PROTECTIVE EFFECT OF COLEUS AROMATICUS LINN , ON RESPIRATORY MARKER ENZYMES DURING CCL4 INDUCED HEPATOTOXICITY
... The present study has been carried out to evaluate the effect of coleus aromaticus leaves on CCl4 induced hepatotoxicity in swiss albino rats. Elevation of ALP and ACP, and decrease in succinate ...
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Effect of roots of gardenia gummifera in methanolic and ethyl acetate extracts on ccl4 induced hepatotoxicity in rat
... that CCL4 intoxication in normal rats elevated the serum levels of SGOT, SGPT, ALKP, TBL and CHL, where as decreased the levels of TPTN, ALB significantly when compared to control indicating acute hepatocellular ...
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Hepatoprotective and Curative Effect of Eclipta prostrata on CCl4 Induced Hepatotoxicity in Albino Rats
... 4 induced elevated enzyme levels in tested groups, indicating the protection of structural integrity of hepatocytic cell membrane or regeneration of damaged liver cells ...
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HEPATOPROTECTIVE EFFECTS OF OLEUROPEIN, THYMOQUINONE AND FRUIT OF PHOENIX DACTYLIFERA ON CCL4 INDUCED HEPATOTOXICITY IN RATS
... A) dilation and congestion ,Necrosis haemorrage and haemosidern deposition , abnormal mitosis and degeneration (Fig 2 B,). This group also showed Bile duct proliferation and portal tract cell infiltration, hepatic artery ...
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THE EFFECT OF CHLOROFORM EXTRACT OF CHASMENTHERA DEPENDENS ON CARBON TETRACHLORIDE (CCL4) INDUCED HEPATOTOXICITY
... The effectiveness of the extract increases as the dosage increases (Tab.3). The extract shows better hepatoprotective and hepato- curative effect at 600mg/kg body weight. The serum concentration of AST and total ...
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HEPATOPROTECTIVE ACTIVITY OF CHENOPODIUM ALBUM LEAVES EXTRACT IN CCl4 INDUCED HEPATOTOXICITY IN RATS
... toxins. Hepatotoxicity or liver dysfunction is a major health problem of society that challenges not only health care professionals or physicians but also the pharmaceutical industry and drug regulatory agencies ...
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Antioxidant and hepatoprotective activity of Flemingia tuberosa Dalzell in CCl4-induced hepatotoxicity in rats
... The liver, which is a vital organ of metabolism, plays a major role in detoxification and elimination of toxicants (Saleem et al., 2018; Sultana et al., 2018). It is incessantly and extensively exposed to xenobiotics, ...
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HEPATOPROTECTIVE ACTIVITY OF PORTULACA PILOSA LINN AGAINST CCL4 INDUCED HEPATOTOXICITY IN RATS
... biochemical parameters such as serum aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP), total bilirubin and gamma glutamate transpeptidase (GGTP). The extract exhibited ...
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BIOEFFICACY OF NYCTANTHES ARBOR TRISTIS LINN , ON CCL4 INDUCED HEPATOTOXICITY IN SWISS ALBINO RATS
... extract was found to be effective in restoring the levels of glucose-6-phosphatase (Table 4). Serum GGT activity is increased with the administration of enzyme inducing drugs, such as phenobarbitone, phenytoin or ...
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HYPOLIPIDEMIC EFFECT OF COLEUS AROMATICUS LINN , ON CCL4 INDUCED HEPATOTOXICITY IN SWISS ALBINO RATS
... Levels of bilirubin altered in group II rats after CCl4 administration as compared to normal controls Coleus aromaticus 300mg/kg/bw extract treatment caused significant recovery in group[r] ...
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HEPATOPROTECTIVE ACTIVITY OF ETHANOL EXTRACTS OF PHALLUSIA NIGRA AGAINST CCL4 INDUCED HEPATOTOXICITY IN RATS
... nigra induced suppression of the increased ALP activity with the concurrent depletion of raised bilirubins suggests the possibility of the extract to have ability to stabilize biliary dysfunction in rat liver ...
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HEPATOPROTECTIVE POTENTIAL OF YOUNG LEAVES OF TRITICUM AESTIVUM LINN AGAINST CCl4 INDUCED HEPATOTOXICITY
... The group treated with Triticum aestivum extract showed a significant decrease in the levels of serum enzymes as compared with standard silymarin treated group.. These studies confirmed [r] ...
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CCl4 induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat
... increased serum concentrations of triglycerides, total cholesterol and LDL, and the decreased level of HDL, were restored to normal values with rutin co-treatment. This may be explained on the basis that rutin has a ...
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The hepatoprotective activity of olive oil and Nigella sativa oil against CCl4 induced hepatotoxicity in male rats
... eration changes in hepatocytes with mild to moderate inflammation and congestion (Fig. 1b). In addition, dis- rupted hepatocytes and inflammatory cellular infiltration were also detected around the blood vessels as a ...
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ANTIHEPATOTOXIC ACTIVITY OF BIHERBAL EXTRACT OF DRIED FRUITS OF PIPER LONGUM AND DRIED STEM OF TINOSPORA CORDIFOLIA AGAINST CCL4 INDUCED HEPATOTOXICITY
... antitubercular drugs like isoniazid, rifampicin etc.) induced hepatotoxicity in rats and mice as they virtually mimic any form of naturally-occurring liver disease. The ability of a hepatoprotective drug to ...
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Asiatic Mangrove (Rhizophora mucronata) – An overview
... Liver is understood to be a major organ in the metabolism, detoxification and excretion of various xenobiotics from the body. The synthetic drugs used for the treatment of liver diseases are inadequate and can have ...
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A REVIEW ON HEPATOPROTECIVE ACTIVITY OFKUSHTHAGHNA MAHAKASHAYA .......
... against CCl4 induced he- patotoxicity in liver tissues. CCl4 induced a significant rise in SGPT, SGOT and ...against CCl4 treated ...cumagainst CCl4 induced ...
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Effect of co administration of zinc and selenium in ccl4 induced heapatotoxicity
... The level of SOD in Gr II decreased significantly as compared to all groups but there was no significant difference in all treated groups with the healthy control group revealing efficacy of antioxidants as an ...
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“A REVIEW OF HEPATOPROTECTIVE NATURAL PRODUCTS” by Fasalu Rahiman O.M*, Rupesh Kumar M, Tamizh Mani T, Mohamed Niyas k, India.
... experimental hepatotoxicity models in laboratory or higher animals, several herbals exerted hepato- protective/curative effects that warrants their clinical ...
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