CD44+/CD133+
Low CD8+ T Cell Infiltration and High PD-L1 Expression Are Associated with CD44+/CD133+ Cancer Stem Cells and Predict an Unfavorable Prognosis in Pancreatic Cancer
... anti-human CD44 antibody (1:500 dilution; DAKO, M7082), or anti-human CD133 antibody (1:500 dilution; Cell Signaling, 3663S) at 4C ...or CD44/CD133-positive cells in each fluorescence image ...
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THE EXPRESSION PROFILING OF ALDH3A1, CD44, CD133 AND TNFRSF9 IN HUMAN BREAST CANCER STEM CELLS
... for CD133 as a marker in Non-small lung cancer (Saadin and White, ...addition, CD44 and CD133 were used as well as surface markers (Jauffret et ...
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Cancer Stem Cell Markers CD44, CD133 in Primary Gastric Adenocarcinoma
... evaluate CD44 and CD133 expressions by immunohistochemistry in 95 primary gastric adenocarcinoma and their relation to clinical and pathological parameters of these ...between CD44 expression and ...
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Prognostic value of the expression of cancer stem cell-related markers CD133 and CD44 in hepatocellular carcinoma: From patients to patient-derived tumor xenograft models
... of CD133, CD90, CD44, ALDH1, CK7, CK19, OCT4, SOX2, vimentin, nestin, CD13 and EpCam were assessed by quantitative reverse transcription-PCR (qRT-PCR) and then were validated using immunohistochemistry in ...
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Clinicopathological significance of CD133 and CD44 expression in infiltrating ductal carcinoma and their relationship to angiogenesis
... of CD133, CD44, and CD82 proteins; both the extent and intensity of immunohistochemical staining were consid- ...of CD133, CD44, and CD82 was considered positive when the scores were ...
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<p>Pretreatment detection of circulating and tissue CD133<sup>+ </sup>CD44<sup>+</sup> cancer stem cells as a prognostic factor affecting the outcomes in Egyptian patients with colorectal cancer</p>
... of CD133 and CD44 were quantitatively measured by FACSCalibur flow cytometer (BD Biosciences) with CellQuest ...of CD133 + CD44 + and CD133 − CD44 − ...
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Expression of CD44 and CD133 in Glioma Stem Cells
... marker CD44 and CD133 in human gliomas. In our study, CD44 expression was significantly correlated with the histological grade of the tumor, but there was no significant correlation between the ...
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Prognostic and Clinical Value of CD44 and CD133 in Esophageal Cancer: A Systematic Review and Meta-analysis
... cancer, CD44 and CD133 are also detectable in other human gastrointestinal malignancies such as gastric cancer (GC) and colorectal cancer ...have CD44 expression as a specific CSC surface marker and ...
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Osteopontin alters DNA methylation through up-regulating DNMT1 and sensitizes CD133+/CD44+ cancer stem cells to 5 azacytidine in hepatocellular carcinoma
... genes. Abnormal DNA methylation at the 5 position of cytosine (5mC) is a well-known epigenetic feature of can- cer [42]. Meanwhile, epigenetic transcriptional regulation is also crucial in the development and maintenance ...
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Coexpression analysis of CD133 and CD44 identifies Proneural and Mesenchymal subtypes of glioblastoma multiforme
... with CD44-FITC (clone DB105, #130-098-210, Miltenyi-Biotec), CD133- APC (clone AC133, #130-098-829, Miltenyi-Biotec) and CD15-PE (SSEA-1, clone MC-480, #13-8813-82, eBioscience) along with the relevant ...
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CD133 CD54 CD44 circulating tumor cells as a biomarker of treatment selection and liver metastasis in patients with colorectal cancer
... is CD133, CD54 and CD44, and the second combination is CD133, CD26 and ...of CD133, CD44, CD54 and CD26 were also examined in the cells suspension derived from fresh tissue of ...
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Cancer Stem Cells In Breast Cancer: A Review
... For solid tumors, the cell surface markers currently used to identify human cancer stem cells includes CD44, CD133, epithelial surface antigen (ESA) and CD24,.. either sin[r] ...
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CD44 and CD24 cannot act as cancer stem cell markers in human lung adenocarcinoma cell line A549
... Despite the identification of a large number of risk factors involved in lung cancer, the incidence of the most common subtype of lung cancer, lung adenocarcinoma, is increasing, so the evaluation of critical aspects of ...
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Original Article β-catenin inhibitors suppress cells proliferation and promote cells apoptosis in PC9 lung cancer stem cells
... SOX2, CD44, CD133 and β-Catenin were detected by Immunofluorescent staining, and mRNA of CSCs marker genes and Wnt/β-Catenin target genes were determined by qPCR ...SOX2, CD44, CD133 and ...
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DSPP-MMP20 gene silencing downregulates cancer stem cell markers in human oral cancer cells
... marker CD44, CD133, ABCG2, ALDH1, PDPN, BMI1 and LRG4 are expressed in OSCC cell ...BMI1, CD133, and CD44 showed similar levels of downregulation, whereas CD133 and LGR4 showed a more ...
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Prognostic value of CD44 expression in patients with hepatocellular carcinoma: meta-analysis
... as CD44, CD133 and ALDH1, are potential indicators of HCC prognosis ...markers, CD44 is the most frequently reported in ...utilised CD44 positivity to isolate cells with stem cell-like and ...
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BMX-ARHGAP fusion protein maintains the tumorigenicity of gastric cancer stem cells by activating the JAK/STAT3 signaling pathway
... 1:500–1000), CD133 (ab216323, 1:1000), CD44 (ab157107, 1:2000), SOX2 (ab92494, 1:1500), JAK2 (ab200783, 1:5000), p-JAK2 (ab32101, 1:2000), STAT3 (ab68153, 1:1500), p-STAT3 (ab76315, 1:2000), Nanog (ab80892, ...
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Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells
... antigens CD133 and CD44 (Sahlberg et ...the CD133 ? CD44 ? subpopulation between these cell lines was determined by ...of CD133 ? CD44 ? subpopulation (*80 %) when compared to ...
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Quantum dots affect expression of CD133 surface antigen in melanoma cells
... with CD133/CD44 markers (C). The expression profile of CD133 and CD44 shown separately for untreated cells (D) and for quantum dot-treated cells with two concentrations, 50 µg/mL (E) and 100 ...
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Original Article Identification of a potential ovarian high-grade serous cancer stem cell marker and its clinicopathological associations
... ALDH1, CD44, CD24 ) and some normal stem cell markers (Nanog, Sox2, Oct4) in serous ovarian tumors (serous cystadenoma (SCA), serous borderline tumor (SBT), low-grade serous carcinoma (LGSC), high-grade serous ...
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