CDG-I
Investigating the Propagation of the Colloidal Dispersion Gel (CDG) in Thick Heterogeneous Reservoirs Using Numerical Simulation
... selecting CDG in field applications, such as shear rate and ...of CDG, which makes the CDG demonstrate shear-thinning behavior [6, 18, ...hand, CDG strength decreases when the salinity ...
17
A case of fatal Type I congenital disorders of glycosylation (CDG I) associated with low dehydrodolichol diphosphate synthase (DHDDS) activity
... (dehydrodolichol reductase or steroid 5α-reductase type 3: SDR5A3) to yield dolichol (Dol) [5] that is subsequently phosphorylated by dolichol kinase (DOLK) to yield DolP (Fig. 1). Dolichol kinase deficiency ...
14
A mutation in the human MPDU1 gene causes congenital disorder of glycosylation type If (CDG If)
... to CDG–Ie) and three defects that alter the process- ing of N-linked glycans on proteins (CDG-IIa to CDG–IIc) (for review see ...named CDG-If, is caused by a mutation in the MPDU1 gene that is ...
8
A novel codon based de Bruijn graph algorithm for gene construction from unassembled transcriptomes
... inGAP-CDG is implemented in C++ as a standalone pro- gram. We have tested it successfully on Mac OS X EI Capitan (10.11) and Linux (Red Hat 6.3 and Ubuntu 16.04) systems. To systematically evaluate the efficiency ...
12
Successful Liver Transplantation and Long-Term Follow-up in a Patient With MPI-CDG
... senting with a severe multisystem in- volvement, including liver disease, endocrine and coagulation abnormali- ties, and multiple neurologic symp- toms. No curative therapy is available in PMM2-CDG. Phosphomannose ...
7
The clinical relevance of glycobiology
... of CDG group I (CDG-If). Group I CDGs involve deficiencies in the assembly of the dolichylpyrophos- phate-linked oligosaccharide N-glycan precursor (Figure 1) and/or its transfer to asparagine ...
5
Volume 3, Issue 4, April 2014 Page 225
... Traditional CDG approach and Script based CDG approach is applied to verify different DSI (Data Storage Interrupt) and ISI (Instruction Storage Interrupt) scenarios of IBM Power 7 ...based CDG ...
7
Defining the Phenotype in Congenital Disorder of Glycosylation Due to ALG1 Mutations
... hypoplasia is seldom detected in ALG1- CDG patients. A growing group of clin- ically recognizable disorders of the early steps of the N-glycan biosynthesis (SRD5A3-CDG, DK1-CDG, and ALG1-CDG) ...
8
Evaluating adherence to recommended diets in adults 1991–2015: revised China dietary guidelines index
... the CDG had better diet quality than males and partici- pants with lower education, with lower income, or who did not know the CDG in each year, the degrees of im- pact were different at the individual ...
12
Three unreported cases of TMEM199-CDG, a rare genetic liver disease with abnormal glycosylation
... [2]. They all carried the same set of compound heterozy- gote mutations, despite no known common family an- cestors. One of the mutations, c.92G > C, was previously reported by Jansen et al. [2], whereas the other one ...
6
First Detection of Shv-Type Extended Spectrum Β-Lactamases in The University Hospital Complex Paediatric Charles De Gaulle (CHUP-CDG) of Ouagadougou in Burkina Faso
... Resistance to antibiotics may be caused by several mechanisms, but the most important of which is the production of β-lactamase that hydrolyzes the β-lactam ring [1, 2]. β-Lactamases (E.C. 3.5.2.6) are the primary agents ...
8
Phosphomannomutase deficiency (PMM2-CDG): ataxia and cerebellar assessment
... The NPCRS is a scale based on the Newcastle Pediatric Mitochondrial Disease Scale recently validated for CDG patients, reflecting cross-usefulness in these two groups of diseases with multiple organ system ...
9
Unsuccessful intravenous D-mannose treatment in PMM2-CDG
... PMM2-CDG is usually a severe multisystem disorder caused by mutations in the gene that encodes phos- phomannomutase 2 (MIM 212065) [1]. This enzyme cata- lyzes the cytosolic conversion of mannose-6-phosphate to ...
6
ALG8-CDG: novel patients and review of the literature
... groups: CDG-I disorders comprise defects in the glycan synthesis (cytosol and endoplasmic reticulum (ER)), and CDG-II disorders defects in glycan processing (Golgi ap- paratus) ...of CDG, e.g. ...
8
COG5-CDG: expanding the clinical spectrum
... The COG complex consists of eight subunits, orga- nized in lobe A (COG1 to COG4) and lobe B (COG5 to COG8). The two lobes are bridged by an interaction be- tween COG1 and COG8. The complex is involved in retrograde ...
10
The Shrunken, Bright Cerebellum: A Characteristic MRI Finding in Congenital Disorders of Glycosylation Type 1a
... that CDG-1a should also be included in the category of CA with cerebellar cortex hyperintensity; in such a context, a globally (rather than just cortical) hyperintense cerebellum on FLAIR, with evi- dence of ...
6
The carbocyclic analog of 2'-deoxyguanosine induces a prolonged inhibition of duck hepatitis B virus DNA synthesis in primary hepatocyte cultures and in the liver.
... In another respect, however, 2'-CDG exhibited antiviral activity unlike that of ddC or PFA: a single 1-day treatment of hepatocytes with 2'-CDG blocked initiation of viral DNA synthesis [r] ...
7
Case Study of Financial Planning and Design in Power Assets Integration
... There are three reasons of assets integration. The first one is strategy adjustment (Wu Hua-ming 2012) [1]. At the new market situation and development period, the enterprises adjust their original developing orientation ...
5
Heparan sulfate and syndecan 1 are essential in maintaining murine and human intestinal epithelial barrier function
... Increased presNonstandard abbreviations used: AAT, α1-antitrypsin; CDG, congenital disorders of glycosylation; dp, degree of polymerization; 2/3-DS-H, 2,3-de-O-sulfated heparin; GAG, gly[r] ...
11
Radical reaction control in the AdoMet radical enzyme CDG Synthase (QueE): consolidate, destabilize, accelerate
... The ring opening reactions of such radicals are one of the fastest class of unimolecular reactions known.[28] This group of extremely fast radical rearrangements have also been used exte[r] ...
10