cell damage
Synthesis and characterization of gold nanorods and their application for photothermal cell damage
... their nanoscale size, nanorods (,80 nm diameter) with peak optical absorption in the near-infrared range were injected subcutaneously or painted on six dorsal spots in three rats. Spots were then illuminated with a diode ...
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Oxidative photoreceptor cell damage in autoimmune uveitis
... oxidative damage; during oxidative stress, 8-OHdG levels increase preferentially in mitochondria as a result of the single-stranded nature of mtDNA, which makes it more susceptible to damage ...DNA ...
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Platelets decrease chemotherapy induced cancer cell damage by increasing cell survival : mechanisms and significance
... mediate cell survival and anti-apoptotic functions against different cytotoxic stresses (Chung ...DNA damage in telomeres require various DNA repair proteins and enzymes such as ataxia telangiectasia ...
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EXCITOTOXICITY AND CELL DAMAGE – A REVIEW
... neuronal cell death characteristic of neurodegenerative diseases, including elevation of intracellular calcium, accumulation of oxidizing free radicals, impairment of mitochondrial function and activation of ...
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Oxygen radicals mediate endothelial cell damage by complement stimulated granulocytes An in vitro model of immune vascular damage
... During hemodialysis, alternative pathway complement activation leads to pulmonary sequestration of granulocytes, with loss of pulmonary vascular endothelial integrity and, at times, protein-rich pulmonary edema. An in ...
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Safety comparison of additives in antiglaucoma prostaglandin (PG) analog ophthalmic formulations
... corneal cell line for a certain time, and the exposure time causing 50% cell damage (CD50), indicated by the ratio of viable cells to total cells was calculated (in ...
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Paf15 expression correlates with rectal cancer prognosis, cell proliferation and radiation response
... DNA damage caused by gamma ...DNA damage response. However, the principles of cell injury caused by gamma radiation ...the cell membrane, and cytosolic proteins. Radiation-induced DNA ...
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ALTERATIONS OF ADP-RIBOSYLATION AND DNA-BREAKS IN AGING BRAIN CELLS
... artifact cell damage during cell separa tions, the relative purity of the cell fractions as judged by high neurofilament content of the neurons and high glutamine synthetase content of the ...
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Original Article Propofol inhibits burn injury-induced oxidative stress injury through SOD2 up-regulation in human dermal microvascular endothelial cells
... to cell injuries in human dermal microvascular endothelial cells (HDMECs), including apoptotic cell death and increased cell ...stress-induced cell damage is closely related to its ...
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... macrophages (45) and TNF-induced NF-kB activation in ML1-a cells (46). In addition, a direct neurotrophic effect of eugenol on BDNF was previously reported since the administration of eugenol in drinking water for two ...
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The effect of edaravone to leukocyte rolling and adhesion molecule expression in microvessels
... and cell damage [3] induced by ROS leads to the formation of arteriosclerotic lesion and microcircular ...oxidative damage of such a biogenic substance leads to the crises and development of ...
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Electrical Impedance Determination of Cancer Cell Viability in a 3-Dimensional Cell Culture Microfluidic Chip
... of cell viability in three-dimensional (3D) cell culture construct is proposed based on on-site electrical impedance measurement in a microfluidic ...3D cell culture has been interpreted for ...
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HDAC8 affects MGMT levels in glioblastoma cell lines via interaction with the proteasome receptor ADRM1
... GBM cell viability and the possibility of developing specific HDAC8 inhibitors provide an opportunity to develop an HDAC8 inhibitor that can cross the blood-brain barrier and target ...
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The plastic liver: differentiated cells, stem cells, every cell?
... the cell of origin for regeneration, then depending on the extent and type of dam- age, several cell types could act as progen- itor populations to mediate ductular reac- tions; therefore, a different ...
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Singular v Dual inhibition of SNF2L and its isoform, SNF2LT, have similar effects on DNA Damage but opposite effects on the DNA Damage Response, Cancer Cell Growth Arrest and Apoptosis
... select cell cycle proteins, ...DNA damage, a DNA damage response, cell cycle arrest and apoptosis selectively in cancer cell ...DNA damage but did not result in a DNA ...
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Mortusewicz, Oliver (2007): Analysis of the DNA damage response in living cells. Dissertation, LMU München: Fakultät für Biologie
... The fact that DNA Ligase I and III although being involved in different repair pathways are both present at microirradi- ated sites raised the question whether they are recruited by similar mechanisms. First hints for ...
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Original Article Overexpression of chromosome kinesin protein KIF4A enhance cisplatin resistance in A549/DDP cells
... Cell lysates were prepared with 50 mmol/L Tris-HCl (pH 8.0), 150 mmol/L NaCl, 0.5% NP-40, 0.5% dexycholate-Na, and 0.1% SDS plus protease inhibitor cocktail from Sigma Inc. Equal amounts of cell lysis ...
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Original Article Xanthohumol inhibits proliferation in lymphoma cells by generation of reactive oxygen species and G0/G1-phase cell cycle arrest
... a cell growth activating pro- tein, and inhibition of Cdc-2 is associated with cell growth ...abnormal cell cycle regulatory networkcould be responsible for the transformed phenotype of malignancy ...
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Ghrelin Regulates Energy Homeostasis Through Discrete Central and Peripheral Signaling Mechanisms
... tissue damage and pathogenic challenges, though unregulated inflammation may transform into chronic and thereby inducing malignant cell transformation in the tissue ...
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Original Article Treatment of human cervical cancer cells with butein leads to apoptosis and DNA damage
... the cell viability, induction of apoptosis and DNA damage in the cervical carcinoma cell ...of cell viability, DNA ladder assays and flow cytometry for apoptosis induction and alkaline comet ...
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