cell death
Pathology of Cell Death
... Cell death is one of the prime events occurring in many of the pathological ...individual cell or group of cells producing changes at tissue and organ ...but cell death occurs under ...
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Programmed cell death and its role in inflammation
... in the context of lung inflammation [74] or via lymphatic vessels [75]. The phagocytosis of pathogens, such as Escherichia coli or Staphylococcus aureus, promotes neu- trophil apoptosis following neutrophil recruitment, ...
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Alternative cell death mechanisms in development and beyond
... interdigital cell death is further strengthened by the syndactyly phenotype of loss-of-func- tion mutants of other WNT inhibitors: Sfrp2 (secreted frizzled-related protein-2) (Morello et ...nonapoptotic ...
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Guidelines and recommendations on yeast cell death nomenclature
... genic fungus that causes life-threatening disease is Asper- gillus fumigatus, which has also been demonstrated to undergo apoptosis under certain conditions [334, 335]. The genome of A. fumigatus codes for two ...
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Computational Analysis of Retrovirus-Inducedscid Cell Death
... scid cell death, provides a poor fit to our experimental data ...scid cell killing can be inhibited by the reverse transcriptase inhibitor zidovudine (AZT) (unpub- lished results), implying that ...
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The endoplasmic reticulum in plant immunity and cell death
... permeability transition and apoptosis signal- ing at mitochondria (Chakrabarti et al., 2011; Gorman et al., 2012; Hetz, 2012). BAX and BAK themselves can interact with IRE1 and promote its ability to activate ASK1 and ...
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Reduction of Cardiac Cell Death after Helium Postconditioning in Rats: Transcriptional Analysis of Cell Death and Survival Pathways
... The use of the colorless, odorless, non- anesthetic noble gas helium in patients with respiratory disease was first de- scribed in 1934 (6). The benefits of helium mixed with oxygen (heliox) were attrib- uted to its ...
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Cell Death and DAMPs in Acute Pancreatitis
... It is also worth mentioning that intra- cellular and extracellular DAMPs may have different mechanisms of action in the pathogenesis of AP (see Figure 4). In- tracellular DAMPs such as HSP and HMGB1 inhibit cell ...
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Cell death in the developing vertebrate retina
... programmed cell death or “cell ...of cell populations during devel- opment, as well as in adult ...deregulated cell death is increasingly recognized as a frequent component in ...
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Mesenchymal stem/stromal cell function in modulating cell death
... lung injury in vivo in a mouse model [73]. Moreover, miRNA transfer via EVs produced by human MSCs alle- viated in vivo renal tubular epithelial RCD that can be apoptosis and/or necroptosis induced in vivo by glycerol or ...
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Necroptosis: a regulated inflammatory mode of cell death
... the cell death includ- ing necroptosis and apoptosis in an animal model of degenerative ...programmed cell death in neuronal cells with low expres- sion of caspase-8; hence, controlling the ...
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Targeting the programmed cell death 1: programmed cell death ligand 1 pathway reverses T cell exhaustion in patients with sepsis
... T cell exhaustion [3]. T cell exhaustion was first described in states of chronic viral infection with persistent high levels of antigen exposure ...cytotoxic cell death in targeted cells ...T ...
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Development and programed cell death in the mammalian eye
... apoptotic cell death with a characteristic spatiotemporally restricted ...regulating cell proliferation and ...programed cell death in the dorsal optic cup is more pronounced in the ...
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A comparison of programmed cell death between species
... ([34-36] and A.-F. Lambin and H.S., unpublished observa- tions). Recently, a Drosophila p53 ortholog was identified by searching the genome database (reviewed in [37]), and it was shown to bind a specific region of the ...
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Ecdysone mediated programmed cell death in Drosophila
... Although not strictly a cell death process, ecdysone is required for remodelling during Drosophila development in the fat body and nervous system. The Drosophila larval fat body is the equivalent of the ...
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Cell death in cancer therapy of lung adenocarcinoma
... As mentioned above, platinum-based drugs used for ADC treat- ment are known to covalently bind DNA, leading to the formation of DNA adducts and activation of the DNA damage response (DNA repair mechanisms, cell ...
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Cytoskeletal Changes in Non-Apoptotic Cell Death
... apoptotic cell death where formation of dynamic membrane protrusions is mediated by the specific cleavage and contraction of actomyosin complex in the presence of caspase-activated Rho kinases ...the ...
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A relational hypothesis analysis for cell death mechanism
... Cell death in the cell development cycle, forms one of the most potential areas for experimental as well as theoretical research and an exciting question as ...the cell death process, ...
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Prevention of beta cell death in chronic pancreatitis
... β cell apoptosis induced by stresses encoun- tered during islet isolation and transplantation fur- ther compromises β cell survival and function after ...β cell dysfunction in chronic pancreatitis ...
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BIOCHEMICAL MECHANISMS OF ETOPOSIDE; UPSHOT OF CELL DEATH
... ABSTRACT: Etoposide is an antineoplastic agent employed for healingvarious malignancies in human. It is a semi-synthetic derivative of podophyllotoxin and was introduced in 1971. The primary mode of action of etoposide ...
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