Cell Fates
Specification of Germ Cell Fates by FOG-3 Has Been Conserved During Nematode Evolution
... germ cell fates so that XX animals could produce first sperm and then ...germ cell fates in ...germ cell fates by the fog genes is a general feature of the ...
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C elegans ISWI and NURF301 antagonize an Rb like pathway in the determination of multiple cell fates
... vulval cell fates, such that lin-1 null mutants have a Muv phenotype (Beitel et ...vulval cell fates, but after phosphorylation by MPK-1 MAPK, LIN-31 promotes vulval cell fates ...
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Interactions between Wingless and Notch during the assignment of cell fates in Drosophila
... of cell fates during development ...a cell adopts or forfeits a fate that is offered to it by running programs of gene expression might be determined by the relative concentrations of Delta and ...of ...
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Opposing Fgf and Bmp activities regulate the specification of olfactory sensory and respiratory epithelial cell fates
... sensory cell line assay (Shou et ...sensory cell line assay, they suggested that Bmp signals are required for neurogenesis (Shou et ...acquired cell fates were not determined in these ...
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Wnt signaling determines ventral spinal cord cell fates in a time dependent manner
... specify cell fates, or it could interact with the Hh signaling pathway, as both Wnt and Shh signaling are active as early as ...and cell fates (Lei et ...mediated cell fate switching ...
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The emergence of the two cell fates and their associated switching for a negative auto-regulating gene
... one cell fate [25, ...organisms, cell com- plexes such as the nuclei inside mammalian cells may give rise to effectively slower processes of the underlying gene regulatory binding/unbinding, due to ...
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Floor plate derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord
... and cell fates are not induced and dorsal genes become expressed ectopically (Chiang et ...ventral cell fates are restored (except FP and p3 cells) (Litingtung and Chiang, 2000; Wijgerde et ...
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Ephrin signaling establishes asymmetric cell fates in an endomesoderm lineage of the Ciona embryo
... It is conceivable that a similar mechanism is used to produce asymmetric cell fates in the A6.3 lineage. As a first test of this possibility, we re-examined Ci-ephrin-Ad expression by in situ hybridization ...
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Regulation of Both Cell State and Gene Expression with Nutrient Gradient as Conserved Mechanism Differentiating the Cell Fates for Embryonic Gastrulation: A Theory
... both cell metabolic state and expressional gene classes as the conserved mechanism differentiating the cell fates for formation of the three germ layers of gastrula in ...phenotypic fates of ...
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Sumoylation of LIN 1 promotes transcriptional repression and inhibition of vulval cell fates
... The function of LIN-1 sumoylation was investigated in animals by reducing the activity of smo-1 using a deletion allele and RNAi and by reducing the activity of ubc-9 using RNAi. Because smo-1 was essential for embryonic ...
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Switching cell fates in the developing Drosophila eye
... their fates by developmental cues presented by differentiating precluster ...wave cell types in precluster cells and draw three ...a cell fate specification code that entails both extrinsic and ...
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MATH5 controls the acquisition of multiple retinal cell fates
... retinal cell fates of Math5-lineage cells imply that these Math5-expressing cells are not yet committed to a particular cell ...in cell proliferation rate could be caused by the loss of RGCs ...
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Distinct GATA6 and laminin dependent mechanisms regulate endodermal and ectodermal embryonic stem cell fates
... As cell-to-matrix interactions take place through direct contact, epithelialization of residual stem cells is precluded, and a single epiblast monolayer develops from cells immediately adjacent to the ...
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Ptf1a determines horizontal and amacrine cell fates during mouse retinal development
... horizontal cell specification pathway Although efforts to unravel the transcription factor code for the specification of retinal neurons have revealed a complex interplay of spatial and temporal control between ...
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The let-60 locus controls the switch between vulval and nonvulval cell fates in Caenorhabditis elegans.
... let-bO(dn) mutations result in defects in male spicules and mating. STERNBERG, unpublished results). These observations suggest that let-60 acts in multiple cells during develop[r] ...
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Repression of Hedgehog signalling is required for the acquisition of dorsolateral cell fates in the zebrafish otic vesicle
... to semicircular canal projections. (A) Dorsal view of a live 20S embryo immediately post-transplant. Rhodamine-dextran-labelled donor otic tissue was visualised fluorescently and is shown as a red overlay. Transplanted ...
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Null Mutations in the lin-31 Gene Indicate Two Functions During Caenorhabditis elegans Vulval Development
... The lin-31 gene is required for the proper specification of vulval cell fates in the nematode Caenorhabditis elegans and encodes a member of the winged-helix family of transcription factors. Members of this ...
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Notch regulates numb: integration of conditional and autonomous cell fate specification
... neuron cell fates The specific activation of the numb CD2 enhancer in the pIIa and pIIIb precursor cells of the bristle lineage suggested to us that it might have a role in specifying the fates of ...
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A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme
... different cell-specific promoters. For example, cell type A expresses gene A, which drives Nigri; cell type B expresses gene B, which drives ...distinct cell populations to understand their ...
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LIN28 alters cell fate succession and acts independently of the let 7 microRNA during neurogliogenesis in vitro
... glial cell fates occurs as it does in ...specific fates and does not function exclusively by blocking let-7 family ...in cell fate succession in vertebrate cells is analogous to its activity ...
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