cell-free DNA
Plasma cell free DNA in patients needing mechanical ventilation
... We registered demographic data, underlying risk fac- tors for the need of MV, physiological and ventilatory data at the study admission, and medications. The clini- cal report form (CRF) data were reported as an attach- ...
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Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis
... plasma cell-free DNA and matched white blood cell germline DNA in 364 blood samples from 217 metastatic prostate cancer ...tumor cell enumeration of synchronous blood ...in ...
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Original Article Serum cell free DNA by branched DNA in patients with gastric cancer
... quantify cell free DNA (cf-DNA) in patients with gastric cancer by a branched DNA (bDNA) assay and to analyze the relationship between serum cf-DNA levels and clinical and ...
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<p>Circulating Cell-Free DNA as Inflammatory Marker in Egyptian Psoriasis Patients</p>
... Circulating cell-free DNA appears following cell damage, and its levels are increased in pathological con- ditions characterized by marked in fl ammation such as cancer, severe sepsis, cerebral ...
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Tumor-Specific Mitochondrial DNA Variants Are Rarely Detected in Cell-Free DNA
... blood-circulating cell-free DNA (cfDNA) as a “liquid biopsy” is being explored for its potential as a screening tool, to establish prognosis, or as a marker for response to ...representing DNA ...
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Prognostic and diagnostic value of eosinopenia, C reactive protein, procalcitonin, and circulating cell free DNA in critically ill patients admitted with suspicion of sepsis
... Circulating cell-free DNA (cf-DNA) has recently received growing attention and has been studied in various chronic and acute disorders ...genomic DNA circulating in peripheral blood. ...
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Circulating cell-free DNA and circulating tumor cells, the “liquid biopsies” in ovarian cancer
... circulating cell-free DNA (cf-DNA) and circulating tumor cells (CTCs) emerging as “ liquid biopsies ” ...tumor DNA (ct-DNA) and CTCs offer unique potentials to better understand ...
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The Prognostic Value of Cell Free DNA in Advanced Non Small Cell Lung Cancer
... DNA detectable in plasma and serum, referred to as cell free DNA (cfDNA) is a potential marker which was discovered in 1948 by Mandel and Metais. It gained little interest until the 1960’s ...
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Circulating cell-free DNA as a prognostic and predictive biomarker in non-small cell lung cancer
... Circulating cell-free DNA (cfDNA), which can be obtained from plasma or serum by non-invasive procedures, has showed great potential to predict treatment response and survival for cancer ...non-small ...
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Cell-free DNA as a diagnostic marker for cancer: current insights
... Abstract: The increasing knowledge of the molecular pathogenesis of cancer and the rapid development of new molecular techniques are promoting the study of early molecular alterations involved in cancer development in ...
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Tumor fraction in cell-free DNA as a biomarker in prostate cancer
... Circulating cell-free DNA (cfDNA) derived from patient plasma is attractive as a noninvasive method for genetic characterization of tumor burden, given its high concordance with matched metastatic ...
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Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen
... serum cell-free DNA (cfDNA) associated with disease progression on tamoxifen treatment in metastatic breast cancer ...patients. DNA from primary tumor and normal tissue and cfDNA from minute ...
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A New Biomarker for Hepatocellular Damage: Plasma Cell Free DNA
... circulating cell-free DNA (cf-DNA) has been detected in patients under pathologic conditions such as cancer, trauma, stroke, pregnancy, autoimmune disorders, and solid organ transplant ...
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<p>Molecular Alterations in Circulating Cell-Free DNA in Patients with Colorectal Adenoma or Carcinoma</p>
... TM cell-free DNA isolation kit (Life Technologies, CA, ...USA). DNA was extracted from white blood cells with the TIANamp blood DNA kit (TIANGEN, Beijing, ...Tumor DNA was ...
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Prognostic utility of admission cell-free DNA levels in patients with chronic obstructive pulmonary disease exacerbations
... cfDNA, cell-free DNA; CRP, C-reactive protein; ED, emergency department; FEV 1 , forced expiratory volume in 1 second; FVC, forced vital capacity; GOLD, Global Initiative for Chronic Obstructive Lung ...
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Noninvasive detection of tumor-associated mutations from circulating cell-free DNA in hepatocellular carcinoma patients by targeted deep sequencing
... plasma DNA was lost to follow-up. The median recurrence-free survival time for patients with tumor-associated somatic mutations detected in plasma DNA was 89 days (range, 34 to 299 days), compared ...
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Cancer gene mutation detection in circulating cell free DNA in blood
... (short DNA oligonucleotides complementary to a specific target DNA sequence) but they additionally have a fluorescent “reporter” dye molecule bound to the ...synthesised DNA molecule (during PCR) the ...
296
Decreased serum cell-free DNA levels in rheumatoid arthritis
... The reduced serum cfDNA levels in esRA might be explained by elevated levels and/or activity of nucleases present in the sera. Deoxyribonuclease I (DNase I) is one of the predominant DNases in human serum [24]. ...
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Cell-free DNA in non-small cell lung cancer
... foetal DNA in the circulation of expectant mothers as a form of non-invasive prenatal (NIP) testing (3, ...tumour DNA (ctDNA), has been challenging for three primary reasons, which include: (1) ...
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<p>Circulating Cell-Free DNA or Circulating Tumor DNA in the Management of Ovarian and Endometrial Cancer</p>
... Researches centered on other genetic alterations or gene panels with several selected genes of cfDNA/ctDNA were also carried out. Cohen et al conducted a proof-of-concept study for subchromosomal with a low coverage ...
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