Cell Plasticity
Cancer Stem Cell Plasticity – A Deadly Deal
... stromal cell types like fibroblasts, endothelial cells, adipocytes and immune cells which are influenced by the cancer cells and vice ...direct cell to cell contacts, there are also factors secreted ...
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Loss of Schwann cell plasticity in chronic inflammatory demyelinating polyneuropathy (CIDP)
... tumor cell lines and leucocytes [31, ...Schwann cell myelination [10, 11, 33], thereby preventing premature or ...Schwann cell plasticity is fur- ther emphasized by findings that axonal ...
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<p>The Exosome And Breast Cancer Cell Plasticity</p>
... stem cell exosome can modulate CSCs niche which is a vital aspect of exosome signaling in ...tumor plasticity in the tumor ...differentiated cell types and that hierarchical models of mammary stem ...
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CD44 enhances tumor aggressiveness by promoting tumor cell plasticity
... Overexpression of CD44 in aggressive Ewing sarcoma and breast cancer cell lines, urged us to investigate functional relevance. Since we previously demonstrated that Ewing sarcoma displays the most overt presence ...
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Biological and clinical significance of cancer stem cell plasticity
... specific cell surface markers, including EpCAM + , CD24 - and CD44 + ...this cell surface phenotype were non-tumorigenic. An in vitro cell culture assay under non-adherent condi- tions for ...
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UHRF1 epigenetically orchestrates smooth muscle cell plasticity in arterial disease
... and Cdkn1b, 2 inhibitors of the cell cycle, a result in line with the decrease of proliferation (Figure 5D). UHRF1 upregula- tion, on the other hand, determined a decrease in Cdkn1a and Cdkn1b mRNA in WT cells as ...
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Pancreatic Beta Cell Plasticity and Involvement of Insulin- Expressing Progenitor Cells
... that these simply represented small islets, or islets with β-cells undergoing apoptosis, rather than reflecting a new source of β-cells derived from a progenitor population (1). Our experiments differ in that; 1) we used ...
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Endothelial cell plasticity: how to become and remain a lymphatic endothelial cell
... , including Flk1 (Kdr; Vegfr2), Tie2 (Tek), Pecam and Tal1, it has been suggested that this transcription factor is at the top of the regulatory cascade that leads to EC specification (Fig. 1) (De Val and Black, 2009; De ...
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Neural crest cell plasticity and its limits
... To investigate the sequential restrictions that might be imposed on trunk NCCs, single quail NCCs were labelled at various times after their migration from neural primordium explanted in vitro (Henion and Weston, 1997). ...
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Satellite Cell Plasticity in the Chicken Embryo
... myogenic cell that share the same morphology and express myogenic and endothelial markers as satellite cells are present in the mouse embryonic dorsal ...endothelial cell precursors during ...satellite ...
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Putting pancreatic cell plasticity to the test
... the plasticity of pancreatic ...major cell type in the pancreas, do not contribute to new b cells formed during pancreatic regeneration (see the related article beginning on page ...pancreatic cell ...
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Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives
... The dynamic nature of the EMT and MET processes along the metastatic cascade implies a finely tuned, regulated control of tumor cell plasticity that can be exerted, at least in part, through ...
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The plastic liver: differentiated cells, stem cells, every cell?
... “back-up” cell sources to maintain organ function following damage would be a favorable evolutionary ...tiple cell sources to provide regenerative capacity would allow flexibility against several forms of ...
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Intermediate filaments: primary determinants of cell architecture and plasticity
... the cell type, morphologically similar but biochemically distinct proteins form highly viscoelastic filament networks with multiple nanomechanical ...in cell plasticity and their established function ...
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Plasticity in the lung: making and breaking cell identity
... robust plasticity has come from cell ablation ...stem cell ablation (Tata et ...secretory cell plasticity through a very short range or a contact-mediated form of ...
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Purkinje cell injury, structural plasticity and fusion in patients with Friedreich’s ataxia
... Purkinje cell plasticity in response to stress/injury is also ...Purkinje cell to convey its out- put information through nearby intact neurons, or be a neuroprotective process to prevent a further ...
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Characterization of the Brain Proteasome and its Interacting Proteins and their Regulation by Neuronal Activity
... The first indication that proteins are not stable entities but undergo constant turnover came from isotope labeling studies in the late 1930s [2]. In the 1950s, protein degradation was shown to be adenosine triphosphate ...
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Study of post-necking hardening identification and deformation-induced surface roughening of metals, Pavlo Knysh
... The hardening curve of a material is one of the three essential ingredients of an associated-flow plasticity theory, along with the yield function and the flow-rule. The uniaxial tension test is perhaps the most ...
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Modelling single cell dynamics of protein networks associated with synaptic plasticity
... synaptic plasticity by using mathematical models and computational methods to understand the complex behaviour of synaptic plasticity, which may be difficult for an unbiased human mind to ...synaptic ...
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Cell cycle re-entry and the plasticity of myotubes in newt limb regeneration
... the MRFs came from studies involving the fusion of myoblasts w ith other cell types (Blau et ah, 1985). Not all cells were equally susceptible to conversion suggesting that either inhibitors of muscle ...
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