Cell-surface receptors
<p>Innate Immunity and Cell Surface Receptors in the Pathogenesis of COPD: Insights from Mouse Smoking Models</p>
... of cell surface recep- tors, proteolysis of cytokine binding proteins, and activation of different speci fi c cell surface receptors, named proteinase- activated receptors ...
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Murine Polyomavirus Cell Surface Receptors Activate Distinct Signaling Pathways Required for Infection
... the cell surface, but how the virus may activate GFR signaling is unclear, given that the capsid does not contain specific GFR binding ...material). Cell surface gangliosides were not required ...
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The NAE Pathway : autobahn to the nucleus for cell surface receptors
... full-length cell surface receptors such as EGFR are translocated from the cell surface to the nucleoplasm, baffling cell biologists to the mechanisms and functions of this ...
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Studies on the role of specific cell surface receptors in the removal of lipoprotein (a) in man
... The binding of 125I-lipoprotein (a) [Lp(a)] to cell surface receptors was studied on cultured human fibroblasts. The results were compared with corresponding data obtained with 125I- low density ...
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Expression of cell surface receptors and oxidative metabolism modulation in the clinical continuum of sepsis
... the surface cell expression of TLR2 and TLR4, the prototypes of PRRs for Gram-positive and Gram-negative bac- teria, CD66b, a selectin with signaling functions [29], and CD11b and CD11c, integrins involved ...
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HIV-2 neutralisation: Interactions between viral glycoproteins and cell surface receptors
... in surface envelope between the molecular clones of ROD A and ROD B used in this chapter: T98I in V I, E138K and E171K in V2, Q310K in V3, and L378F, K403R and R414I in V4 (Reeves and Schulz, ...
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Nuclear trafficking of secreted factors and cell-surface receptors: new pathways to regulate cell proliferation and differentiation, and involvement in cancers
... alternative translation initiation. LMW FGFs are secreted and need to be re-internalized to be routed to the nucleus. In contrast to LMW isoforms, HMW forms (21–34 kDa) are not excreted from the cell and are ...
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Integrin Targeted Delivery of Gene Therapeutics
... of cell surface adhe- sion receptors seem particularly attractive target for enhancing the efficiency and selectivity of delivery of antisense and siRNA ...heterodimeric cell surface ...
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Extracellular matrix as target for antitumor therapy
... their cell surface receptors, mainly integrins, have an active role at all steps of tumor ...uncontrolled cell proliferation, disruption of cellular interac- tion, migration, and settlement in ...
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Why Integrin as a Primary Target for Imaging and Therapy
... Integrin-mediated cell adhesion is involved in many essential normal cellular and pathological functions including cell survival, growth, differentiation, migration, inflammatory responses, platelet ...
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Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis
... from cell surface receptors retained their ligand binding ability and were transcribed in human normal and malignant ...Tie receptors [41-43] has been reported in RA, this is the first ...
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Cell surface immune receptors: the guardians of the plant’s extracellular spaces
... host cell cytoplasm and some could be recognized in the apoplast by extracellular receptors structurally similar to ...immune receptors that recognize extracellular located pathogen effectors are ...
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Synergistic antiviral and antiproliferative activities of Escherichia coli-derived human alpha, beta, and gamma interferons.
... It is obvious, however, that potentiation of IFN-induced biological activities cannot be predicted solely on the basis of interactions with cell surface receptors, since others have show[r] ...
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Direct in vitro effect of a sulfonylurea to increase human fibroblast insulin receptors
... insulin receptors on nontransformed human fibroblasts in tissue ...of cell surface receptors was observed with a maximum effect (19% increase) seen at ...
5
The human fibroblast receptor for gp86 of human cytomegalovirus is a phosphorylated glycoprotein.
... In addition to its role in fusion of cytomegalovirus with the cell membrane, the 92.5-kDa HCMV gp86 fibroblast membrane receptor, like other cell surface receptors for viral glycoprotein[r] ...
5
Cell surface immune receptors: the guardians of the plant’s extracellular spaces
... immune receptors that recognize extracellular located pathogen effectors are sometimes classified as PRRs [5], which we think is equally confusing because each has a very narrow recognition ...these cell ...
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6.6 Viruses - HIV
... • The glycoproteins bind to the CD4 receptors of the T helper cells allowing the lipid membrane of the virus to fuse with the cell surface membrane.. How the virus replicates[r] ...
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Biocontrol of Pseudomonas Aeruginosa Biofilm Using Bacteriophages
... The host range of a phage reflects its ability to (lytically) infect strains within a given test panel where narrow host range phages infect a small number of strains and broad host range phages infect a wide range of ...
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Transforming Growth Factor Beta Receptor Partitioning: Molecular Mechanisms and Functional Consequences
... though TRI contains a shorter extracellular domain than TRII and cannot bind ligand in the absence of TRII (39). Akin to TRII, TRI also contains a serine/threonine kinase intracellular domain and exists as a ...
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Expression of Nef from unintegrated HIV 1 DNA downregulates cell surface CXCR4 and CCR5 on T lymphocytes
... for cell viability and hence the likelihood of productive infection ...entry receptors may provide similar benefit, as is also seen with integrating infections ...
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