cell survival
The Role of Autophagy in Cell Survival and Cell Death
... the survival of cancer cells once tumours have ...promote cell survival under conditions of poor nutrient supply, as often faced by solid tumours and metastasising cancer ...during cell death, ...
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The effect of exercise induced localised hyperthermia on tendon cell survival
... The cell survival fraction in these experiments cannot therefore predict directly what might occur in vivo during high- speed locomotion because of the differing conditions mentioned ...mammalian ...
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Flavonoids in modulation of cell survival signalling pathways
... The cell signalling is a critically important mechanism for the multicellular organisms including human beings particularly for inflam- matory, cardiac, and neurological ...inducing cell survival and ...
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A Boltzmann-Tsallis approach towards cell survival curve in Radiobiology
... the cell survival curve obtained above and the experimental result, a modification needs to be made involving the dose ...of cell survival curve, the dose is the energy deposited in each ...
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MAPK1 is required for establishing the pattern of cell proliferation and for cell survival during lens development
... mediated survival signal is, at least in part, mediated through MAPK1 ...regulate cell survival? One possibility is by regulating the level of survivin, which is a member of the inhibitor of ...
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Effects of glutamine deprivation on oxidative stress and cell survival in breast cell lines
... tumourigenic cell lines including human lymphoid tumour cell line and prostate cancer cell line (PC3) [7, ...in cell viability and increased induction of ...enhanced cell death in ...
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ZFAT is a critical molecule for cell survival in mouse embryonic fibroblasts
... In summary, our report demonstrated that ZFAT is a critical regulator for cell survival in MEFs, and that the apoptosis induced by a depletion of ZFAT may be involved in BCL-2-mediated pathways. Further ...
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Inhibition of endothelial cell survival and angiogenesis by protein kinase A
... (35). Cell death is also induced by environmental stress, activation of death receptors, and loss of contact with the ECM ...regulate cell shape as well as enzymes that are important for DNA repair and ...
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Mitochondrial Compartmentalized Protein Folding and Tumor Cell Survival
... mitochondrial proteotoxic stress, and mount a multipartite response that attempts to preserve cell survival and restore homeostasis (Fig. 1). Much of our knowledge about organelle-initiated UPR comes from ...
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Naive T cell survival and homeostasis analysis of monoclonal and polyclonal T cell populations
... Another situation where low affinity interactions between MHC and TCR results in better survival of T cells is during thymic differentiation. The low avidity reactions involved in the positive selection of these ...
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A study of schwann cell survival, proliferation and interaction with neurons
... stem cells (Stemple and Anderson, 1992; Shah et al., 1994; Davis and Temple, 1994). Together, this evidence indicated that variation in at least some molecular signals in the environment may play a role in lineage fate ...
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Tumour stromal interactions: Integrins and cell adhesions as modulators of mammary cell survival and transformation
... of cell–cell adhesion is essential for tumor invasion ...different cell adhesion molecules such as P-cadherin, CD44, and Ep-Cam [37–39], and readily ...Enhanced cell–cell interactions ...
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Red cell survival studies in hereditary spherocytosis
... the survival t½ in compatible normal ...influenced cell survival since cells with high fragility were rapidly sequestered in the normal ...both cell shape and a selective reticuloendothelial ...
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Metabolic alterations caused by HNF1β expression in ovarian clear cell carcinoma contribute to cell survival
... decreases cell proliferation of OCCC in normal oxygen condition ...support cell survival with unstable oxygen supply in cancer microenvironments [12, 16, 27, ...a survival advantage especially ...
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Platelets decrease chemotherapy induced cancer cell damage by increasing cell survival : mechanisms and significance
... mediate cell survival and anti-apoptotic functions against different cytotoxic stresses (Chung ...to cell cycle arrest and senescence, or apoptosis (Herbig, Jobling et ...
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HP1γ function is required for male germ cell survival and spermatogenesis
... tually all cells (Figure 4a) and is distinct from the staining pattern of transcriptional intermediary factor (TIF)1β, a HP1γ-interacting protein, in wild-type testes, where pre- leptotene and spermatogonia are ...
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The control of CD4+CD25+Foxp3+regulatory T cell survival
... and make cytokines themselves. Even though our data do not show that Foxp3 determines cytokine dependence directly, we feel that there is a strong implication that the presence of Foxp3 inversely correlates with cytokine ...
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Interleukin-9 promotes cell survival and drug resistance in diffuse large B-cell lymphoma
... lymphoma cell-lines, including the DLBCL cell-lines LY1 and LY8, mantle cell lymphoma (MCL) cell-lines Mino and SP53, as well as the human acute T cell leukemia cell-line ...
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HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target.
... selective inhibitor of the HSF1 pathway, CCT251236, in human myeloma cell lines, primary 77.. patient myeloma cells and a human myeloma xenograft model.[r] ...
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AFG3L2 supports mitochondrial protein synthesis and Purkinje cell survival
... We provide evidence that AFG3L2 is required autonomously in PCs to protect against degeneration. Remarkably, 3 weeks after establishment of Cre recombinase expression in PCs, a large num- ber of neurons lacking AFG3L2 ...
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