Cellular metabolism
Sestrins orchestrate cellular metabolism to attenuate aging
... Through regulation of the AMPK-mTORC1 signaling axis, the Sestrins promote metabolic adaptation of cells in response to diverse stress insults. Sesn1 and Sesn2, as p53-inducible genes, mediate DNA damage-induced ...
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Autophagy in cellular metabolism and cancer
... and metabolism, and autophagy inhibition leads to tumor cell death (101, 105, ...promoting cellular metabolism in the context of defec- tive autophagy (76, ...
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The regulation of cellular metabolism by tumor suppressor p53
... lipid metabolism In addition to glucose metabolism, p53 regulates many other aspects of cellular metabolism, including glutamino- lysis and fatty acid oxidation (Figure ...
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Optimal autoregulation of the cellular metabolism
... Cell metabolism is treated as a harmonious system of reactions rigidly organized in space and co-ordinated in time, possessing certain special qualities characteris[r] ...
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Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress
... mitochondrial metabolism under acidosis (Figure ...the cellular acidosis response (Additional file 5: Figure S4F) with TXNIP induction as positive control ...impacts cellular survival under ...
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Viral hijacking of cellular metabolism
... cell metabolism, there have been studies examining how the host cell metabolic environment af- fects the progression of some oncogenic viral infections, such as ...glycolytic metabolism and lipogenesis ...
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CALCIUM METABOLISM OF BONE IN VITRO INFLUENCE OF BONE CELLULAR METABOLISM AND PARATHYROID HORMONE
... This finding, together with the similarity in Ca concentration at 2 hours between living and heatinactivated samples Figure 1 suggests that in both experiments the reduction was the resu[r] ...
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A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia
... (LDL) cholesterol, as observed in patients with familial hyper- cholesterolemia (FH), are a prominent risk factor for developing atherosclerosis (Ference et al., 2017). FH is predominantly caused by loss-of-function ...
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Picornaviruses and RNA Metabolism: Local and Global Effects of Infection
... of cellular metabolism to the hijacking of specific host functions used during viral translation, RNA replication, and other steps of infection by picornaviruses, such as human rhinovirus, coxsackievirus, ...
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Some Aspects of the Respiration of Six Species of Fish From Uganda
... This makes for the efficient cellular metabolism essential for such a fast and powerful predator, but the respiratory surfaces must be bathed in water containing high tensions of dissolv[r] ...
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Continuous multiparametric monitoring of cell metabolism in response to transient overexpression of the sirtuin deacetylase SIRT3
... of cellular metabolism with biosensor chips allows for a rapid analysis and visualisation of single protein effects on cellular metabolism for an extended period of time in living cells in a ...
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Bioenergetic modulation with dichloroacetate reduces the growth of melanoma cells and potentiates their response to BRAFV600E inhibition
... of cellular metabolism towards aerobic ...aerobic metabolism of normal cells, but occurs in the context of an adequate oxygen supply ...of metabolism in cancer cells is a highly com- plex and ...
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Age-related changes in the transcriptome of antibody-secreting cells
... in cellular metabolism of T cells and is expressed higher on aged B cells, we tested splenic ASCs for metabolic parameters and found that they carry higher levels of cellular reactive oxygen species ...
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Amplification of the Inflammatory Cellular Redox State by Human Immunodeficiency Virus Type 1-Immunosuppressive Tat and gp160 Proteins
... of cellular metabolism and the body response to the induced environmental ...the cellular damaging effects of HIV-1 Tat and gp160 proteins it was necessary to develop a technique which would allow ...
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Intrinsic Factor mediated Absorption of Cobalamin by Guinea Pig Ileal Cells
... block cellular metabolism, virtually all cellular radioactivity could be removed by washing the cell surface with EDTA or ...residual cellular radioactivity was extracted and analyzed by gel ...
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ABCC6- a new player in cellular cholesterol and lipoprotein metabolism?
... About twenty ABC transporters are involved in the carriage of compounds derived from lipid- or cholesterol metabolism and are important for reverse cholesterol transport (RCT) and phospholipid- and cholesterol ...
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Combined [18F]DPA-714 micro-positron emission tomography and autoradiography imaging of microglia activation after closed head injury in mice
... the cellular correlate of [ 18 F] DPA-714 binding by combined in vivo μPET, ex vivo autoradiography, and IBA-1 immu- nohistochemistry in a mouse model of closed head ...
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Modeling of Biomass Production of Haematococcus pluvialis
... Although it is expected that an increase in light inten- sity helps accelerate the rate of growth of microalgae biomass, it also causes a reduction in the amount of Haematococcus pluvialis biomass produced due to the ...
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Cancer proliferation and therapy: the Warburg effect and quantum metabolism
... Our analysis rests on certain critical differences in the metabolic rate of cells utilizing fermentation and respiration. First, we observe that there are significant differences in the metabolic efficiency between ...
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Arenavirus Infection Induces Discrete Cytosolic Structures for RNA Replication
... of cellular markers, cells were fixed with PBS-buffered ice-cold 4% paraformaldehyde (Electron Microscopy Sci- ences) for 1 h and processed as described above, with the exception that those stained with Bodipy TR ...
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