Central nervous system inflammation
A Central Role for CD4+ T Cells and RANTES in Virus-Induced Central Nervous System Inflammation and Demyelination
... Immunohistochemistry. Primary antibodies (diluted in phosphate-buffered sa- line containing 2% normal goat serum [NGS]) used for immunohistochemical detection of cellular antigens were as follows: rat anti-mouse CD4 ...
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Investigation of ADAMTS 9 expression in models of central nervous system inflammation
... Protein was transferred to Hybond-C nitrocellulose membrane (Amersham Biosciences, Amersham, UK) at 150 V (300 mA) for 1 h in the presence of lx NuPAGE transfer buffer (Invitrogen) (with 10% methanol). All western blot ...
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Endoplasmic reticulum stress and inflammation in the central nervous system
... In mammalian cells, the central proteins involved in ini- tiating this evolutionarily conserved response are activat- ing transcription factor 6 (ATF6), inositol-requiring 1 α (IRE-1 α )[r] ...
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The crucial role of Erk2 in demyelinating inflammation in the central nervous system
... The animals were sacrificed under deep anesthesia and then perfused through the left ventricle with PBS. Then, the brain was quickly removed from the skull and the portion comprising the cortex, corpus callosum, stri- ...
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Inflammation modulates expression of laminin in the central nervous system following ischemic injury
... As COX-2 is one of the critical contributors to micro- glial activation [4], we assessed the extent of neuronal death and other parameters in COX-2 −/− mice (COX- 2KO) relative to wild-type (WT) animals. COX-2KO mice ...
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High-fat diet feeding differentially affects the development of inflammation in the central nervous system
... the central nervous system (CNS) and will in- crease the incidence of CNS pathologies such as cogni- tive impairments [16], Alzheimer ’ s disease [17], stroke [18], or dementia ...its central ...
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Toxoplasma gondii Infections Alter GABAergic Synapses and Signaling in the Central Nervous System
... the nervous system is to regulate the timing, magnitude, and flow of excitatory neurotransmission, and defects in GABAergic signaling cause seizures ...
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T cells in multiple sclerosis and experimental autoimmune encephalomyelitis
... the central neurones and their myelin sheaths, in particular, but also their ...recovery, inflammation and oedema in the central nervous system (CNS) resolves and it is ...
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Evans syndrome associated with sterile inflammation of the central nervous system: a case report
... Although these results supported other studies dem- onstrating reduced serum immunoglobulin (Ig)G, IgM and IgA levels in patients with ES, pointing towards dysregulated cellular und humoral immunity [4], the significance ...
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Fighting the Monster: Applying the Host Damage Framework to Human Central Nervous System Infections
... tissue inflammation, such as sCD27/T-cell ratios, suggested that inflammation was not re- stricted to the CSF alone but was also present within the meninges or brain parenchyma ...
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STAT1 Signaling in Astrocytes Is Essential for Control of Infection in the Central Nervous System
... The ability to directly address the role of astrocytes in the pathogenesis of TE has been a challenge (18). However, in mice that lack glial fibrillary acid protein (GFAP), an intermediate fila- ment expressed by ...
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Collaboration of Antibody and Inflammation in Clearance of Rabies Virus from the Central Nervous System
... Development of CNS inflammation in CVS-F3-infected mice. While differences in the ability to clear CVS-F3 from the brain may be the consequence of variability in VNA production, it is also conceivable that ...
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Chronic Pain in Multiple Sclerosis: An Overview
... to inflammation; chronic or intermittent neuropathic pain related to central nervous system (CNS) lesions; pain secondary to spasticity, spasms and muscle cramps from higher motor neuron ...
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The Roles of Lysosomal Exocytosis in Regulated Myelination
... the central nervous system and Schwann cells in the peripheral nervous ...the central nervous system and P0 in the peripheral nervous system, transport from ...
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Current Status of Therapeutic Approaches against Peripheral Nerve Injuries: A Detailed Story from Injury to Recovery
... CNS: Central Nervous system; PNS: Peripheral Nervous system; PPNIs: Preoperative peripheral Nervous system; WD: Wallerian degeneration; BMSCs: Bone marrow-derived ...
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Key words
... The most widely accepted theories of the pathophysiology of OAB are the neurogenic and myogenic ones. They are not mutually exclusive, and can be regarded as complementary. The basic mechanisms underlying these two ...
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The Dynamic Role of Breathing and Cellular Membrane Potentials in the Experience of Consciousness
... the central nervous system, peripheral nervous system, cardiorespiratory system, and various other tissues (such as muscles and sensory organs) in the physiology of consciousness ...
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revised chapt09 lecture
... The peripheral nervous system (PNS) consists of the cranial and spinal nerves that arise from the central nervous system and travel to the . remainder of the body[r] ...
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Original Article Selective central nervous system tropism of primary central nervous system lymphoma
... Primary Central nervous system lymphoma (PCNSL) is most frequently a diffuse large B cell lymphoma (DLBCL), which is confined to the Central nervous system ...
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chapt09_lecture.ppt
... The peripheral nervous system (PNS) consists of the cranial and spinal nerves that arise from the central nervous system and travel to the remainder of the body.. T[r] ...
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