Cerebellar granule cells
The alpha 6 subunit of the GABA(A) receptor is concentrated in both inhibitory and excitatory synapses on cerebellar granule cells
... The subcellular distribution of the a6 subunit of the GABA, receptor on cerebellar granule cells has been revealed by pre- and postembedding immunogold methods using three affin[r] ...
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Poly (ADP-ribose) polymerase plays an important role in intermittent hypoxia-induced cell death in rat cerebellar granule cells
... Ba: Cells were costained with Hoechst (blue), TUNEL (green), and Tau ...of cerebellar granule ...Ca: Cells were costained with Hoechst (blue), PI (red), and Tau ...
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Model cerebellar granule cells can faithfully transmit modulated firing rate signals
... However, granule cells are known for their non-linear and resonant synaptic and intrinsic properties that could potentially impede linear signal ...electrophysiological granule cell properties and ...
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Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down’s syndrome
... mouse cerebellar cDNA that was made and quantified using standard ...from cerebellar vermis (frozen in liquid nitrogen immediately upon dissec- tion and stored at −80°C) of wild-type mice using TRIzol W ...
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Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway
... of cerebellar development make it one of the best studied systems for ...the cerebellar neurons (e.g. Purkinje cells, deep cerebellar nuclei and interneurons) arise at a ventricular zone ...
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Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions.
... deficient cerebellar granule cells (Fig 2B, Fig ...deficient cerebellar granule cells in the presence of Shh, which is the “ major coordinator ” of growth and patterning of the ...
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Caspase-3 mediated cell death in the normal development of the mammalian cerebellum
... that cerebellar NOND was apoptotic in several mammals, including all the most commonly used laboratory species and humans ...the cerebellar granule cells when the PNs were ablated by ...
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Dissociation of locomotor and cerebellar deficits in a murine Angelman syndrome model
... of granule cells is reduced in AS ...Purkinje cells, but also in cerebellar Golgi cells. Golgi cells provide tonic as well as phasic inhibition onto granule cells ...
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A patch-clamp study of native and recombinant glutamate receptors
... in cerebellar granule cells were not matched by any of the recombinant receptors ...in granule cells contributed to the formation of the high-conductance ...the granule cell ...
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Cerebellum and forebrain derived stem cells possess intrinsic regional character
... of cerebellar stem cells, we sought to compare their differentiation potential to those stem cell populations known to exist in the ...adult-derived cerebellar neurospheres give rise to neurons with ...
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Transit amplification in the amniote cerebellum evolved via a heterochronic shift in NeuroD1 expression
... Despite these insights, relatively little is known about the emergence of transit amplification as a developmental strategy. In the cerebellum, there is a dramatic disjunction between developmental strategies used in ...
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Bmp2 antagonizes sonic hedgehog mediated proliferation of cerebellar granule neurones through Smad5 signalling
... deep cerebellar nuclei, the white matter and the cerebellar cortex, is well described as playing several important roles in the control of motor ...mature cerebellar cortex arises late in development ...
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Overlapping functions of the cell adhesion molecules Nr-CAM and L1 in cerebellar granule cell development
... of cerebellar size of adult Nr-CAM knockout mice Three pairs of 3–6-mo-old Nr-CAM / and their littermate Nr-CAM / (129SvEv genetic background) females were used for analysis of cerebellar ...and ...
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The role of support cells in the growth and differentiation of neurones in the abdominal ganglion of Aplysia
... Preventing metamorphosis and granule material release the ganglion remains embedded in granule-filled support cells by withholding the macroalgal substrate blocks half of the increase in[r] ...
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Pharmacological and biophysical characteristics of voltage-dependent calcium channels in rat cerebellar granule neurones
... The past few years have seen major advances in our understanding of the structural and functional properties of neuronal voltage-dependent Ca^^ channels. A major factor contributing to the wealth of literature that has ...
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The mechanisms for pattern completion and pattern separation in the hippocampus
... would by pattern association from the backprojecting synapses to the cortical pyramidal cells become associated with whichever cortical cells were being made to fire by the forward inputs. Then later on, ...
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‘Medusa head ataxia’: the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ITPR1 and anti-CARP VIII
... autoimmune cerebellar ataxia; AChR: acetylcholine receptor; ADEM: acute disseminated encephalomyelitis; AF: Alexa Fluor®; AGNA: anti-glial cell nuclear antibodies; AMPA: α -amino-3-hydroxy-5-methyl- ...
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Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus
... picolinic acid are neuroprotective [13]. In the hippocam- pus, kynurenine aminotransferase, the enzyme that pro- duces kynurenic acid, is abundant in both neurons and astrocytes [24-26]. Furthermore, we demonstrated that ...
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Synaptic inhibition of cerebellar Purkinje cells
... Lugaro cells lay within 40 |am o f the nearest Purkinje cell somata, either directly below a Purkinje cell or below the space between two Purkinje ...Lugaro cells whose morphology was examined extended from ...
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The amount of astrocytic GABA positively correlates with the degree of tonic inhibition in hippocampal CA1 and cerebellum
... glial cells, dentate gyrus had more than 20% of astrocytic ...glial cells (20~40%) in thalamus and ...glial cells than other sub-regions of ...glial cells in cerebellar cortex contain ...
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