Cerebral Ischemia
Bench to bedside review: A possible resolution of the glucose paradox of cerebral ischemia
... during cerebral ischemia, we postulated that glucose loading evokes a short-lived (30–60 min) systemic response (hormonal or other) that, when occurring simultane- ously with an ischemic episode, is capable ...
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RIG-I contributes to the innate immune response after cerebral ischemia
... RLR signaling is typically involved in the production of type I IFNs such as IFN-α following RNA viral infec- tions. We have previously shown that in the central nervous system (CNS), RLR signaling contributes to the ...
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Pathophysiology of Cerebral Ischemia: Role of Oxidative/Nitrosative Stress
... after cerebral ischemia, whereas those with a defi- ciency show increased injury, proving that excessive oxygen radical production is fundamental to ischemic brain injury, while in case of NOS activation ...
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Transient cerebral ischemia Association of apoptosis induction with hypoperfusion
... of cerebral blood flow and reversibil- ity of the ischemic ...of cerebral perfusion alone did not lead to a signifi- cant induction of apoptosis in cat brain during the duration of reperfusion that we ...of ...
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Expression of MICU1 after experimental focal cerebral ischemia in adult rats
... In this study, we also measured the mRNA level of MICU1 at brain regions from bregma 1 to −1 mm after cerebral ischemia. Real-time quantitative PCR (qPCR) was used to detect the change of MICU1 mRNA expres- ...
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Perioperative cerebral ischemia promote infiltrative recurrence in glioblastoma
... a cerebral ischemia during resection and thereby presumably exposing residual tumor cells to ...of cerebral hypoxia caused by ischemic stroke can be much better ...Since cerebral ...
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The assessment of behavioural deficits following focal cerebral ischemia
... focal cerebral ischemia and the neural basis to covert attention and motivation in the ...middle cerebral artery, proving to be an adaptable technique across different strains of rat and permitting ...
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TREM2 protects against cerebral ischemia/reperfusion injury
... of cerebral ischemia injury, the role of triggering receptor expressed on myeloid cells 2 (TREM2) in the pathogenesis of ischemic stroke remains to be ...the cerebral cortex after middle ...
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In Vivo Theranostics at the Peri-Infarct Region in Cerebral Ischemia
... The use of theranostics in neurosciences has been rare to date because of the limitations imposed on the free delivery of substances to the brain by the blood-brain barrier. Here we report the development of a ...
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Pharmacological treatment of delayed cerebral ischemia and vasospasm in subarachnoid hemorrhage
... a cerebral aneurysm is the cause of 6% to 8% of all cerebrovascular accidents involving 10 of 100,000 people each ...delayed cerebral ischemia (DCI) is observed in 30% of patients, with a peak on the ...
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Previous chronic cerebral infarction is predictive for new cerebral ischemia after carotid endarterectomy
... The mean age of the 51 studied patients was 68.8 ± 8.4 years (range 46–82). There were 37 men (72.5 %) and 14 women (27.5 %). Arterial hypertension (58.8 %) and hyperlipidemia (52.9 %) were the most frequent risk ...
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Anti-inflammatory effects of Chinese medicinal herbs on cerebral ischemia
... after cerebral ischemia include the neurotoxic cytokines interleukin-1b (IL-1b), tumor necrosis factor-alpha (TNF-a), neuroprotective cytokines interleukin-6 (IL-6), interleukin-10 (IL-10) and trans- ...
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Protective effect of Daming capsule against chronic cerebral ischemia
... myocardial ischemia reper- fusion injury, reducing myocardial infarctions [18, 14], and restoring aortic endothelial dysfunction [17, ...with cerebral ischemia ...
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Targeting the purine salvage pathway in in vitro models of cerebral ischemia
... The use of brain slices has revolutionised the study of the mammalian central nervous system and has now become a standard preparation in many laboratories and in many areas of neuroscience. Their versatility lends them ...
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Focal cerebral ischemia in the TNFalpha-transgenic rat
... The suture-occlusion model of focal cerebral ischemia is feasible in the TNFα-Tg rat and produces a larger mean volume of infarction than in non-Tg littermates. We spec- ulate that the greater infarct ...
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The new language of cerebral ischemia
... of cerebral isch- emia at their earliest stages in the human brain by diffusion-weighted and hemodynamically weighted MR ...of cerebral ischemia, with diffusion declining by 40% to 50% (76, ...
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The Role of Zinc in Cerebral Ischemia
... Alternatively, other studies have at- tempted to monitor dynamic changes in zinc levels during cerebral ischemia in the absence of therapeutic interventions. Sorensen and colleagues (31) set out to examine ...
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Original Article Role of miRNA-185 in cerebral ischemia-reperfusion injury
... Rats were fasted 24 hours before surgery with free drinking water. 30 rats were anesthetized by intraperitoneal injection with 10 percent of chloral hydrate at the dose of (weight * 3 + 0.1) ml. Then, the common carotid ...
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Neuroprotective effect of nicotine and simvastatin on cerebral ischemia induced cognitive impairment
... separated. Cerebral ischemia was induced by clamping both the arteries with the help of aneurysm ...of cerebral ischemia, the clips were removed from both the arteries to allow the reflow of ...
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Transesophageal echocardiography in patients with cryptogenic cerebral ischemia
... Method: Patients with cryptogenic cerebral ischemia (ischemic stroke, IS, and transient ischemic attack, TIA) were included. The initial work-up included a neurological examination, EEG, cCT, cMRT, 12-lead ...
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