Cerebral ischemic injury
Adiponectin: a pivotal role in the protection against cerebral ischemic injury
... reported that adiponectin could promote focal angiogenesis in cerebral ischemic injury. They showed that after MCAO mice receiving intracerebral injection of adeno-associated viral vector carrying ...
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The effect of picroside II on the expressions of AQP4, MMP9 and COX2 in cerebral ischemic injury in rats
... of cerebral ische- mia, AQP4 expression increased in the glial cell, espe- cially in the foot processes surrounding capillary vessels, which promoted the occurrence of cerebral edema ...acute ...
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To Optimize the Therapeutic Dose and Time Window of Picroside II in Cerebral Ischemic Injury in Rats by Orthogonal Test
... in cerebral ischemic injury in ...different ischemic time with different ...in cerebral ischemic ...in cerebral ischemic injury were ischemia ...in ...
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Methylene Blue Reduces Acute Cerebral Ischemic Injury via the Induction of Mitophagy
... ACI injury, we first measured the effect of MB on mitophagy in an OGD model to simulate ACI injury in ...ACI injury was al- tered after mitophagy was ...
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Isoflurane and Ketamine/Xylazine Anesthesia do not Influence the Neuroprotective Effects of Simvastatin in a Model of Permanent Cerebral Ischemic Injury in C57BL/6J Mice
... underwent ischemic injury by permanent coagulation of the Middle Cerebral Artery (MCA): Group A (n=11) animals were anesthetized with ketamine/xylazine, Group B (n=9) with isoflurane, Group C (n=9) ...
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The neuroprotective mechanisms of ginkgolides and bilobalide in cerebral ischemic injury: a literature review
... of ischemic strokes, declines in cogni- tive efficiency in domains including executive function, immediate recall, delayed recall, speech, divergent think- ing, attention and concentration, and visual-constructive ...
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Electroacupuncture preconditioning reduces cerebral ischemic injury via BDNF and SDF 1α in mice
... focal cerebral ischemia induced by EA pretreatment is mediated by BDNF and ...the cerebral vascular endothelium, was observed throughout the ischemic cortex following ...
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Original Article Effects of miR-223 on cerebral ischemic injury and angiogenesis in diabetic rats
... After neurobehavioral function evaluation, rats were anesthetized with 3% Pentobarbital Sodium and sacrificed by cervical dislocation. The brain was removed rapidly and frozen for 20 min at -20°C. Then the brain was cut ...
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Toll-like receptors in cerebral ischemic inflammatory injury
... in cerebral ischemic injury can ...in ischemic brain stroke have mainly focused on ischemic damage in TLR4- and, to a lesser extent, TLR2-mutant ...in ischemic stroke, it has not ...
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receptor antagonist, on chronic brain injury after focal cerebral ischemia in rats
... of cerebral ischemic ...ischemic injury. Using this regimen, the study found the efficacy of post-ischemic HAMI 3379 and Pranlukast on both morpho- logical and functional ...focal ...
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Original Article Cerebrovascular protective effect of combination of Tetradrine and Atorvastatin against cerebral ischemia-reperfusion injury in rats via inhibition of inflammatory mediators
... against cerebral ischemia-reperfusion injury in ...in ischemic cerebral ...the cerebral ischemic injury via inhibition of NF-κB and other pro- inflammatory mediators ...
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Function and mechanism of toll-like receptors in cerebral ischemic tolerance: from preconditioning to treatment
... the cerebral ischemic injury of the central nervous sys- ...whole cerebral ischemia model further confirmed that the cerebral ischemic damage in TLR4-knockout mice was also ...
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Original Article Roles of lncRNA UCA1-miR-18a-SOX6 axis in preventing hypoxia injury following cerebral ischemia
... in cerebral ischemia, we stud- ied the expression of UCA1 under hypoxia and the effects of its suppression on preventing hypoxia injury in neuronal PC-12 ...induced injury in PC-12 cells were further ...
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The Need for Objective Assessment of the New Imaging Techniques and Understanding the Expanding Roles of Stroke Imaging
... acute cerebral ischemia can be generalized into three se- quential stages: 1) flow abnormalities; 2) cellular dysfunction; and 3) structural breakdown (19–20, 36, ...regional cerebral blood flow (CBF) that ...
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Individualized perfusion targets in hypoxic ischemic brain injury after cardiac arrest
... persistent cerebral oligemia despite restoration of cardiac ...perivascular cerebral edema culminating in increased cerebrovascular resistance and de- creased CBF ...ongoing cerebral ischemia and ...
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Do Apparent Diffusion Coefficient Measurements Predict Outcome in Children with Neonatal Hypoxic Ischemic Encephalopathy?
... examinations were reloaded from the archives. Trace maps were used to calculate ADC values in all regions of interest. Because of image defor- mation in the DWI acquisition, regions of interest were identified on the ...
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Original Article SCM-198 protects ischemic brain injury via accelerating the recovery of brain glucose metabolism, ameliorating the damage of neurons and inhibiting the activation of microglia
... As we know, blood-brain barrier (BBB) disrup- tion during MCAO can cause secondary brain injury, including irreversible neuron losses, inju- ry and degeneration. According to our previous- ly study, SCM-198 could ...
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Imaging Guided Acute Ischemic Stroke Therapy: From “Time Is Brain” to “Physiology Is Brain”
... acute ischemic stroke is disappointingly low, and effective treatments are making a minor impact on this major public health ...the ischemic penumbra, a key concept in stroke physiology, though it is ...
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Local brain temperature manipulation system and physiological parameters (R2', CBF and ADC) measurements in acute stroke
... For this device, a thermo probe is required as the real time feedback signal. Since a direct measurement of brain temperature with a thermo-probe causes tissue damage and induces susceptibility artifacts in MR images, ...
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Reduced microvascular thrombosis and improved outcome in acute murine stroke by inhibiting GP IIb/IIIa receptor mediated platelet aggregation
... in cerebral infarct volumes and an improvement in postischemic cerebral blood ...carotid injury model (29) and to reduce platelet- mediated cyclical blood flow reductions in a primate carotid ...
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