CeY/sub 2/Fe/sub 5/O/sub 12/
In vitro toxicity of Fe<sub>m</sub>O<sub>n</sub>, Fe<sub>m</sub>O<sub>n</sub>-SiO<sub>2</sub> composite, and SiO<sub>2</sub>-Fe<sub>m</sub>O<sub>n</sub> core-shell magnetic nanoparticles
... -Fe 2 O 3 . Using TEM characterization, Fe m O n -SiO 2 composite flake-like and SiO 2 -Fe m O n core-shell IONPs demonstrated spherical shape with mean ...
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Preparation of Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles coated with gallic acid for drug delivery
... different pH levels which are similar to the pH of the stomach and the pH of the blood. Generally, the pH of the stomach varies from 1–2 to 4–5. After eating, the stomach releases proteases and hydrochloric ...
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The effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> on immune function in normal ICR mice
... group) Fe 3 O 4 -MNPs, were dissolved in normal saline and intravenously (iv) injected into mice ...for 5 minutes at 4 ° C to separate plasma and blood ...
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Effect of interaction of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and artesunate on apoptosis of K562 cells
... 3-(4, 5- dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) (Ameresco, Solon, OH); Z-VAD-FMK (Beyotime Biotechnology); RPMI 1640 medium and fetal calf serum (GIBCO, USA); artesunate (Guilin ...
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Biocompatibility of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and their cytotoxic effect on MCF-7 cells
... saline). Fe 3 O 4 was washed twice with distilled water, dried, and suspended using normal saline (final concentration ...for 5 minutes at 2500 rpm; the supernatant was then removed and OD values ...
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Polyetherimide-grafted Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging
... (Figure 5) at room temperature (about 300 ...of Fe 3 O 4 @SiO 2 ...the Fe 3 O 4 @SiO 2 and Fe 3 O 4 @SiO 2 /PEI ...the Fe 3 O 4 @SiO ...
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Reversal of multidrug resistance by magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice
... 3 O 4 copolymerizating DNR delivered by vena caudalis ...C, 5-BrTet 2.5 mg/(kg ⋅ day) combined with DNR 1 mg/(kg ⋅ day), 5-BrTet was administered one hour before DNR; in group D, NP-Fe 3 ...
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Effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4 </sub>and 5-bromotetrandrine on reversal of multidrug resistance in K562/A02 leukemic cells
... Human chronic myeloid leukemia in blast crisis cell line, K562, and its resistant cell line to ADM, K562/A02, were both cultured in a RPMI 1640 medium (Gibco/BRL, Gaithersburg, MD, USA) supplemented with 10% fetal calf ...
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In vitro and in vivo targeting imaging of pancreatic cancer using a Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoprobe modified with anti-mesothelin antibody
... a 5-year survival rate ,5% mainly due to lack of early diagnosis and effective ...nanoprobe Fe 3 O 4 @SiO 2 modified with anti-mesothelin antibody (A-MFS) was prepared to target cells ...
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Pharmacokinetic parameters and tissue distribution of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles in mice
... After intragastric administration, 0.2–0.5 mL of blood from one mouse in each group were collected into an ethylene- diaminetetraacetic acid tube by enucleating eyeballs at the time points of zero minutes, hours 1, 3, ...
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Combination of PEI-Mn<sub>0.5</sub>Zn<sub>0.5</sub>Fe<sub>2</sub>O<sub>4</sub> nanoparticles and pHsp 70-<em>HSV</em>-<em>TK</em>/GCV with magnet-induced heating for treatment of hepatoma
... with 5% skimmed milk at room temperature for 1 hour, incubated with anti-p-Stat3, anti-Bax, or anti-Bcl-xL antibodies (1:1,000 dilution) or anti- β-actin antibody (1:1,000, final dilution) at 4° C overnight, then ...
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Magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and chemotherapy agents interact synergistically to induce apoptosis in lymphoma cells
... 3 O 4 , adriamycin + MNP-Fe 3 O 4 , daunorubicin + MNP-Fe 3 O 4 , dexamethasone + MNP-Fe 3 O 4 , and RPMI 1640 alone were added to these cells and cultured at 37 ° C for ...
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Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... doxorubicin 5 mg/5 mL was emulsified in 10 mL dichloromethane, in which 120 mg of the copolymer and 4 mg magnetic nanopar- ticles had been dissolved, using a probe homogenizer or soni- cation at 20,000 rpm ...
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The changes of T lymphocytes and cytokines in ICR mice fed with Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... cells/mL with RPMI-1640. The adjusted cells were placed in a 96-well microtiter plate in 200 µ L aliquots and cultured in the presence of T-lymphocytes mitogen (5 µ g/mL Con- canavalin A [ConA]) (Sigma Chemical ...
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Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... for 12 days by releasing DNR and 5-Br-Tet from Fe 3 O 4 ...over 12 days, and nanoparticles were observed in the tumor tissue on histopathologic examina- tion after a single treatment ...
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Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... 3 O 4 (1 µ g/mL, 10 µ g/mL, or 100 µ g/mL) for 24 hours in the absence or presence of N-acetylcysteine (NAC; 10 mM) (Sigma-Aldrich Co); NAC was added 3 hours before treatment with MgNPs-Fe 3 O 4 ...H ...
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Synthesis of composite magnetic nanoparticles Fe<sub>3</sub>O<sub>4</sub> with alendronate for osteoporosis treatment
... Reagents used in cell culture include albumin solution from bovine serum (Sigma-Aldrich Co.), ascorbic acid (C 6 H 8 O 6 ; Sigma-Aldrich Co.), Dulbecco’s Modified Eagle’s Medium (DMEM; high glucose with l ...
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Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... with 5% dry milk and exposed to rabbit polyclonal antibody anti- KCNQ1 (H-130: sc-20816, [Santa Cruz Biotechnology, Santa Cruz, CA USA]; dilution 1:2,000 in bovine serum albumin (BSA) 5%), rabbit polyclonal ...
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Biological responses to core–shell-structured Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>-NH<sub>2</sub> nanoparticles in rats by a nuclear magnetic resonance-based metabonomic strategy
... neopterin; o-hPa, ortho-hydroxyphenylacetate; Pa, picolinate; Pag, phenylacetylglycine; Pan, pantothenate; PaP, adenosine 3′,5′-diphosphate; Pc, phosphocholine; Phe, phenylalanine; p-hPa, ...
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Magnetic nanoparticle of Fe<sub>3</sub>O<sub>4</sub> and 5-bromotetrandrin interact synergistically to induce apoptosis by daunorubicin in leukemia cells
... Human leukemia cell line K562 and its adriamycin-selected Pgp-overexpressing subline K562/A02 were obtained from the Institute of Hematology, Chinese Academy of Medical Sciences (Tianjin, China). Both cells were cultured ...
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