CF mice
Effect of genistein on basal jejunal chloride secretion in R117H CF mice is sex and route specific
... assess the effect of dietary genistein or daily sc genistein injections on intestinal function in R117H CF mice. In this study, we have compared the effects of 4 week consumption of a genistein-enriched ...
11
Acute intratracheal Pseudomonas aeruginosa infection in cystic fibrosis mice is age-independent
... MHH mice [49]. Corre- spondingly, if CF mice were exposed intranasally with ...of CF mice and the bacter- ial load increased within the first hours ...congenic CF and ...
15
Airway disease phenotypes in animal models of cystic fibrosis
... derstanding CF pathogenesis and developing therapeutic strategies. Given that CF affects multiple organs includ- ing the gastrointestinal tract, lungs, pancreas, liver, and reproductive organs, it desirable ...
12
Expression of S100A8 correlates with inflammatory lung disease in congenic mice deficient of the cystic fibrosis transmembrane conductance regulator
... Bc-CF mice were main- tained in identical environments, the differential levels of S100A8 expression between the two strains is likely influ- enced by secondary genetic factors acting on neutrophils (either ...
11
CONSUMING GENISTEIN IMPROVES SURVIVAL RATES IN THE ABSENCE OF LAXATIVE IN ΔF508-CF FEMALE MICE
... soy. Mice homozygous for the ∆F508 mutation are characterized with severe intestinal disease and require constant laxative treatment for ...∆F508 CF mouse model on laxatives for survival, thereby improving ...
24
In vivo monitoring of lung inflammation in CFTR deficient mice
... in CF is important for initiating the anti-inflammatory treatment and monitor- ing its ...in mice often rely on invasive ex vivo measure- ments which causes the death of the animal and are consequently ...
9
Caerulein-induced acute pancreatitis in mice that constitutively overexpress Reg/PAPgenes
... and CF mice, fol- lowed by recovery and overexpression at later times as the tissue recovers from ...in mice with caerulein-induced pancreatitis occurs during the first hours, followed by a rebound ...
11
Inhibition of High-Mobility Group Box 1 Protein (HMGB1) Enhances Bacterial Clearance and Protects against Pseudomonas Aeruginosa Pneumonia in Cystic Fibrosis
... from mice that were inoculated with ...either CF patients or CF mice sig- nificantly improved macrophage func- tion and reduced bacterial loads in the ...from CF patients was found to ...
9
Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas aeruginosa
... of CF, however, fail to develop pulmonary disease ...on mice homozygous for the S489X mutation of the CFTR gene using an animal model of chronic Pseudomonas endobronchial ...or CF mice. The ...
7
Influence of the cystic fibrosis transmembrane conductance regulator on expression of lipid metabolism-related genes in dendritic cells
... in CF DC could be due to increased tran- scription or stability of the mRNA in the DC ...from CF Mice Bone marrow cells from CF mice showed a delay in the early phase of differentiation ...
15
Molecular Epidemiology of Mycobacterium abscessus, with Focus on Cystic Fibrosis
... Two of the four patients (no. 1 and 11) harboring cluster A1 were siblings, both suffering from CF. The older sibling (no. 1) has been permanently colonized by M. abscessus since 2000 and has clinical disease ...
8
A<sub>2A</sub> adenosine receptor-mediated increase in coronary flow in hyperlipidemic APOE–knockout mice
... All animals were cared for in accordance with protocol (No. 07-0801) approved by the Animal Care and Use Com- mittee of the Health Science Center at West Virginia Uni- versity, which conforms to the Guide for the Care ...
10
Genetic Variation at the Tomato Cf-4/Cf-9 Locus Induced by EMS Mutagenesis and Intralocus Recombination
... in Cf-4/Cf-9 trans-heterozygotes are delimited by horizontal double-headed arrows relative to the ATG of Hcr9-9E (plants G640, G641, H889, H881, and V408) and Hcr9-9D (plant ...
12
CFTR and differentiation markers expression in non CF and delta F 508 homozygous CF nasal epithelium
... 508 CF nasal polyps were not significantly different from those of non-CF ...the CF group. The histological observations of non- CF and CF nasal polyp tissue indicated that the huge ...
12
Activation of chloride transport in CF airway epithelial cell lines and primary CF nasal epithelial cells by S-nitrosoglutathione
... with CF with class I and II mutations, and it has been demonstrated that even residual CFTR activity was a good prognostic factor for pulmonary status in this subset of patients ...from CF patients, since ...
9
Statistical Estimation of the Degree of Contamination with Mycotoxins in Feed for Cattle
... c. Highest concentration was established for AFB1, which is a warning sign, knowing that aflatoxicosis has an increased incidence in cattle; d. Of the 8 kinds of feed examined, soy grits is only fodder that has not been ...
5
A data model of the Climate and Forecast metadata conventions (CF-1.6) with a software implementation (cf-python v2.1)
... CF describes variation within cells by use of “cell meth- ods”. By default, it is assumed that intensive quantities ap- ply at grid points, e.g. temperature values apply at the spa- tial points and instants of ...
28
ANTIHYPERGLYCEMIC AND ANALGESIC ACTIVITIES OF ETHANOLIC EXTRACT OF CASSIA FISTULA (L ) STEM BARK
... 20 mice were divided into four groups (each group comprises five ...control mice received vehicles (1% Tween 80 in saline), Group II served as standard group and received diclofenac (10 mg/kg ...of ...
8
The B Lymphocyte Differentiation Factor (BAFF) Is Expressed in the Airways of Children with CF and in Lungs of Mice Infected with Pseudomonas aeruginosa
... infected mice show that homeostatic chemokines including CXCL13, CCL19 and CCL21 are essential for effective pulmonary defence, regulating B and T cell recruitment to the airway, stimulating dendritic cells and ...
7
Pathogenesis, imaging and clinical characteristics of CF and non-CF bronchiectasis
... In CF, it is often associated with mucus plugging, bronchial wall thickening, and small airway disease [128, ...in CF bronchiectasis depending on pancreas insufficiency (PI), with PI patients illustrating ...
11