chagasic patients
Differential cytokine profiling in Chagasic patients according to their arrhythmogenic status
... Chagasic patients were diagnosed with two different sero- logical tests (ELISA IgG and indirect haemagglutination), according to WHO ...criteria. Patients aged 26 to 72 years (mean ...criteria. ...
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Use of the Trypanosoma cruzi Recombinant Complement Regulatory Protein To Evaluate Therapeutic Efficacy following Treatment of Chronic Chagasic Patients
... chagasic patients. For this evaluation we used a group of 31 patients which were treated with benznida- zole according to the guidelines of the Chagas’ disease division of the Brazilian Health ...
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Chagasic patients are able to respond against a viral antigen from influenza virus
... pathway should be responsible of the absence of a potent and antigen focused cellular immune response [8,14]. Due to the parasite’s genetic complexity and a high degree of polymorphism among strains, only a few human CD8 ...
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Characterising the KMP 11 and HSP 70 recombinant antigens' humoral immune response profile in chagasic patients
... acute chagasic (AC) patients from Santa Catarina state who were diagnosed by IgG and IgM immunofluorescence assays were included ...chronic chagasic patients were also enrolled who were ...
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Probing Population Dynamics of Trypanosoma cruzi during Progression of the Chronic Phase in Chagasic Patients
... chronic chagasic patients from different regions of the states of Minas Gerais and Goia ´s in ...two patients were initially characterized (by rRNA genotyping) as ...two patients who presented ...
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New Treatments for Chagas Disease and the Relationship between Chagasic Patients and Cancers
... Abstract: Chagas disease is an infectious illness with a broad distribution throughout the South American and African continents, importantly influencing human morbidity and mortality and a controversial relationship ...
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Short term follow up of chagasic patients after benznidazole treatment using multiple serological markers
... treated patients, variations in reactivity against the individual antigens were ...in patients grouped as being in the indeterminate stage, a statistically significant decrease in reactivity against KMP11 ...
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Host cell invasion and oral infection by Trypanosoma cruzi strains of genetic groups TcI and TcIV from chagasic patients
... Background: Outbreaks of acute Chagas disease by oral infection have been reported frequently over the last ten years, with higher incidence in northern South America, where Trypanosoma cruzi lineage TcI predominates, ...
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Anti Trypanosoma cruzi and anti laminin antibodies in chagasic patients after specific treatment
... The analysis of Table 1 and Table 2 shows that both epimastigote and trypomastigote antigens were recognized by antibodies present in the sera of cured CSA-negative patients, as demonstr[r] ...
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Trypanosoma cruzi Discret Typing Units (TcII and TcVI) in samples of patients from two municipalities of the Jequitinhonha Valley, MG, Brazil, using two molecular typing strategies
... from patients of the Jequitinhonha Valley, Minas Gerais, Brazil, resultant from the amplification of the 3' region of the 24S α rDNA ...from chagasic patients of the Jequitinhonha Valley, Minas ...
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Anti-Trypanosoma cruzi Immunoglobulin G1 Can Be a Useful Tool for Diagnosis and Prognosis of Human Chagas' Disease
... The patients included in this study ranged from 24 to 77 years of ...from chagasic patients with chronic ...the chagasic patients were divided into three different categories, namely, ...
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The C-terminal region of Trypanosoma cruzi MASPs is antigenic and secreted via exovesicles.
... chronic chagasic patients, while negative sera came from healthy controls from the Gorgas Commemorative Institute for Public Health in Panama (n = ...from chagasic patients were serum-positive ...
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Different serological cross reactivity of Trypanosoma rangeli forms in Trypanosoma cruzi infected patients sera
... from patients with indeterminate form of the disease (data not shown), to strong plasma membrane labeling alone when tested with serum from patients with cardiac involvement ...all chagasic ...
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Mapping of B-Cell Epitopes in a Trypanosoma cruzi Immunodominant Antigen Expressed in Natural Infections
... Trypanosoma cruzi is a parasitic protozoan that causes Cha- gas’ disease, an ailment without effective drug treatment that affects 16 million to 18 million people in South and Central America. Chagas’ disease is ...
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Use of a 24 kilodalton Trypanosoma cruzi recombinant protein to monitor cure of human Chagas' disease
... treated chagasic patients considered parasitologically cured on the basis of persistently negative tests of hemocultures and lytic ...these patients were termed dissociated because their sera, ...
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PCR Assay for Monitoring Trypanosoma cruzi Parasitemia in Childhood after Specific Chemotherapy
... in patients without reductions in antibody ...evaluating chagasic patients after specific chemotherapy dem- onstrated that PCR is more reliable and sensitive than xeno- diagnosis for assessment of ...
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Serological diagnosis of Chagas' disease: a potential confirmatory assay using preserved protein antigens of Trypanosoma cruzi
... 12 chagasic patients and were positive by immunologic tests (IHAT, IFT, ELISA, dot ELISA, and IDT); however, one serum sample gave a false-negative result only by ...a chagasic patient and a sample ...
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Design, Construction, and Evaluation of a Specific Chimeric Antigen To Diagnose Chagasic Infection
... of patients with autoimmune or related parasitic ...of chagasic patients with cardiopathies, quantification of these Abs was proposed to be useful to evaluate the patient’s status in terms of ...
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Intramyocardial transplantation of cardiac mesenchymal stem cells reduces myocarditis in a model of chronic Chagas disease cardiomyopathy
... Infection of C57BL/6 mice was performed by intraperi- toneal injection of 100 trypomastigotes of the myotropic Colombian T. cruzi strain [20]. Groups of 10 chronic chagasic mice (6 months post-infection) were ...
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Expression in Escherichia coli of a dominant immunogen of Trypanosoma cruzi recognized by human chagasic sera
... Human chagasic antibodies immunopurified on clone H49 were reacted with metacyclic trypomastigotes T, amastigotes A, and epimastigotes E from T.. Antibodies immunopurified on nonrecombin[r] ...
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