Changes in tissue intergrity and microenvironment components
Changes in the tumor immune microenvironment in resected recurrent soft tissue sarcomas
... This study had both weaknesses and strengths. The study included post-operative treatment for 17 patients between the 1st and 2nd surgery; however, post-operative treatment was not an independent predictive factor for ...
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The role of the tissue microenvironment in the regulation of cancer cell motility and invasion
... motility, tissue invasion, transendothelial migration and metastasis ...shape changes, secretion of proteolytic enzymes and chemo- kines, and force ...
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Adipose Tissue And Its Role In Modulating The Mammary Tumor Microenvironment
... adipose tissue contribute to enlarging the myofibroblast population during breast tumorigenesis was previously ...ECM components (collagen and fibronectin) with enhanced α-SMA-mediated contractility, which ...
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Role of Tissue Microenvironment in Recruiting Macrophages During Apoptosis-induced Proliferation
... undead tissue secrete other cytokines, such as the Toll ligand Spätzle or JAK/STAT ligand Unpaired, which have been implicated in different aspects of tumorigenesis and wound repair [138, 245, ...undead ...
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Mesenchymal stem cell 3D encapsulation technologies for biomimetic microenvironment in tissue regeneration
... Therefore, tissue regeneration requires various environ- ments depending on a tissue type, because of their distinct ECM parameters, ...biochemical components such as growth factors including BMP-2, ...
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Acute tissue death (white syndrome) affects the microenvironment of tabular Acropora corals
... acute tissue loss, resulting in apparently healthy tissue bordering on exposed ...and tissue structure of WS-affected tabular acroporid corals were assessed by O 2 microelectrodes and histological ...
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Tumour Tissue Microenvironment Can Inhibit Dendritic Cell Maturation in Colorectal Cancer
... individual components of the tumour conditioned media (CCL2, CXCL1, CXCL5) could modulate dendritic cell maturation or cytokine secretion in response to ...
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Tertiary Lymphoid Tissue in Colorectal Cancer: A Key Player in the Tumour Immune Microenvironment
... Colorectal cancer [CRC] is the third most commonly diagnosed cancer and one of the leading causes of cancer mortality in the world. It accounts for over 9% of all cancer incidence [1, 2]. The World Health Organization ...
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Molecular and cellular changes in the tumour microenvironment during IL-12 therapy
... Tumour areas consisted of mainly tumour cells, stroma consisted of fibroblast-like cells and extracellular matrix and necrosis was composed mainly of cell fragments and cell debris. The modified Chalkley array consists ...
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Native-mimicking in vitro microenvironment: an elusive and seductive future for tumor modeling and tissue engineering
... into tissue microenvironments as part of the bio- logical functions of the cells and as a mechanism to maintain tissue homeostasis ...pathological changes within ECM highly resembling human disease ...
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Obesity induced inflammatory changes in adipose tissue
... have evolved from common ances- tors. The best example of this is the Drosophila fat body, which contains the mammalian homologs of liver, the hemapoietic system, and other immune components. Recently, it was ...
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An investigation of the relationship between the components of tumour microenvironment, signal transduction pathways and outcome in breast cancer
... For TMA construction, tumour-rich areas on full H&E stained sections were identified and marked by a qualified pathologist (JJG), and were matched to formalin-fixed paraffin- embedded blocks. The procedure for ...
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The relationship between androgen receptor, components of tumour microenvironment and survival in breast cancer molecular subtypes
... on tissue microarrays ...Ltd.). Tissue samples were counterstained with haematoxylin and blued with Scots Tap Water Substitute, dehydrated through graded alcohol and xylene and mounted with Di-N-Butyl ...
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Transglutaminase 2 mediates the biomechanical properties of the colorectal cancer tissue microenvironment that contribute to disease progression
... tumour microenvironment, which is linked to aggressive cancer cell behaviour by enhancing biomechanical ...biomechanical changes were associated with observed alterations to collagen fibre structure, ...
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Tumor suppressor ARF regulates tissue microenvironment and tumor growth through modulation of macrophage polarization
... TAMs have been described to induce the formation of new blood vessels through the expression of potent pro-angiogenic molecules, including VEGF or TGF-β. In addition, ARF has been reported to regulate endothelial cell ...
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Epigenetic changes in localized gastric cancer: the role of RUNX3 in tumor progression and the immune microenvironment
... The t-test for sample independence was used to study the correlation between the average gene, amplicon, or CpG methylation levels with clinicopathological and molecular features, and to compare differences in ...
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ACADEMIC INTERGRITY POLICY
... 2. Select the appropriate control design tools and tests procedures to analyze a control system. 3. Compile design report that documents simulation results, component selection, prototype construction, laboratory ...
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Tissue factor in tumor microenvironment: a systematic review
... spliced tissue factor; ATRA: All-trans retinoic acid; CCL2: CC chemokine ligand; Clk: CDC-2 like kinases; CRC: Colorectal cancer; CSCs: Cancer stem cells; Cyr61: Cysteine-rich 61; EGFR: Epidermal growth factor ...
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Role of extracellular microenvironment on regenerative bone tissue capacity
... of tissue-specific gene promoters has enabled the identification and lineage tracing of various stem cell types in vivo, such as progenitor cells (Grcevic et ...
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Studies on engineered microenvironment for manipulating cells in tissue regeneration
... The effect of extracellular matrix (ECM) proteins such as collagen type I, collagen type IV, gelatin, laminin, fibronectin, Matrigel (a mixture of laminin, collagen type IV[r] ...
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