CHANNEL GENE
Regulation of neuronal excitability through pumilio dependent control of a sodium channel gene
... for rapid fluctuations in synaptic excitation (Baines, 2003). Un- doubtedly, however, neurons must also adapt to changes in syn- aptic excitation that persist over the longer term, and we specu- late that additional ...
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Variants in the human potassium channel gene (KCNN3) are associated with migraine in a high risk genetic isolate
... ion channel gene (KCNN3) is located in the vicinity of the familial hemiplegic migraine type 2 locus on chromosome ...This gene is expressed in the central nervous system and plays a role in neural ...
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Support for calcium channel gene defects in autism spectrum disorders
... calcium channel gene with properties similar to those of CACNA1G ...this channel subtype may eventually help provide insight into the means by which the T-Type genes could predispose to ...
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Ion channel gene expressions in infertile men: A case-control study
... ion channel gene expressions by impaired progressive motility and morphology patients compared to the ...ion channel functions on the sperm cell because it may lead to develop new treatment ...
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Liddle disease caused by a missense mutation of beta subunit of the epithelial sodium channel gene
... wild-type and the b deletion mutant (R564stop) found in the original kindred described by Liddle. The experiments in Fig. 4 show that the b subunit R564 deletion mutant compared with rENaC wild-type displays a ...
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Mutations in the voltage gated sodium channel gene of anophelines and their association with resistance to pyrethroids – a review
... the gene expression) or through mutations in the coding gene portion of the enzyme, producing the more efficient metabolization of the insecticide ...
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Genomic Organization and Evolution of Alternative Exons in a Drosophila Calcium Channel Gene
... the protein sequences encoded by the alternative exons IS4a and IS4b and the mammalian sequences for the same region.. (b).[r] ...
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KvLQT1 and KCNE1 K+ Channel Gene Polymorphisms in Long QT Syndrome
... potassium channel, KQT-like subfamily, member 1 (KCNQ1), encodes pore-forming voltage gated K+ channel subunit KvLQT1 and is widely expressed in myocardial ...
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Mutations in sodium channel gene SCN9A cause a spectrum of human genetic pain disorders
... More recent genetic studies have identified the voltage-gated sodium-channel Nonstandard abbreviations used: CIP, channelopathy-associated insensitivity to pain; DRG, dorsal root ganglio[r] ...
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Dosage effects of a Drosophila sodium channel gene on behavior and axonal excitability.
... Dosage effects of other putative sodium channel genes: Because pura+ is a sodium channel structural gene (LOUCHNEY, KREBER and GANETZKY 1989), we interpret these do[r] ...
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Myocardial ischemia induces differential regulation of KATP channel gene expression in rat hearts
... thought to be a complex composed of an inward rectifier po- tassium channel (Kir6.1 and/or Kir6.2) subunit and the sul- fonylurea receptor (SUR2). This channel is activated during myocardial ischemia and ...
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Voltage-gated proton channel in a dino agellate
... proton channel gene, express the protein heterologously, characterize the electro- physiological properties of the protein, and compare key struc- tural elements with those elements in known proton ...
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Relationship between insecticide resistance and kdr mutations in the dengue vector Aedes aegypti in Southern China
... Ae. aegypti is present in many residential areas of Southern China. In recent years, regular monitoring has revealed that many Chinese populations of Ae. aegypti have become resistant to pyrethroid insecticides [18, 19], ...
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Clinical, genetic and expression studies of human CNS channelopathies
... Evidence for ion channel involvement in epilepsy has been collected from studies o f mouse mutants with epilepsy. In 1998, Smart and colleagues showed that deletion o f the mouse homologue o f the K y l .l ...
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First evidence of retained sexual capacity and survival in the pyrethroid resistant Sitobion avenae (F.) (Hemiptera: Aphididae) SA3 super-clone following exposure to a pyrethroid at current field-rate.
... The grain aphid Sitobion avenae is a prolific pest of cereal crops worldwide, controlled effectively with pyrethroid insecticides. However, the classic knock down resistance (kdr) mutation, L1014F on the S. avenae sodium ...
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Expression of diverse Na+ channel messenger RNAs in rat myocardium Evidence for a cardiac specific Na+ channel
... Na+ channel cDNA probe ...Na+ channel, thereby identifying pCSC-1 as a related member of the family of Na+ channel ...Na+ channel gene probes, expression of the rat brain-1 Na+ ...
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smedinx 11 is a planarian stem cell gap junction gene required for regeneration and homeostasis
... The largely unknown mechanisms that regulate adult stem cells probably involve signals from neighboring differentiated cells. Gap junction channels providing direct cell-cell communication via small molecules are a ...
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Salt sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel
... CYP4A gene sub families as functionally relevant AA epoxygenases and ωhydroxy lases, respectively (8–11), and implicated them in the control of renal function and blood pressure ...(Cyp4a10) gene causes ...
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Caballero Martínez, Amelia (2019): The role of the potassium channels KV1.3 and KCa3.1 in arteriogenic smooth muscle cell proliferation. Dissertation, LMU München: Medizinische Fakultät
... the channel in proliferative versus contractile SMCs, albeit in models of neointima hyperplasia, such as the murine femoral artery balloon injury model (Cidad, Moreno-Dominguez et ...
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Proton Channel Activity of Influenza A Virus Matrix Protein 2 Contributes to Autophagy Arrest
... FIG 2 Proton channel activity contributes to influenza A virus M2-induced autophagosome accumulation in a dose-dependent manner. (A) TREx-293 cells carrying tetracycline-inducible amantadine-sensitive H5N1-M2 ...
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