Chapter Four: Endothelial and platelet microparticles
Transcellular activation of platelets and endothelial cells by bioactive lipids in platelet microparticles
... the microparticles and are mimicked by arachidonic acid iso- lated from ...However, platelet activation requires prior metabolism of microparticle arachidonic acid to thrombox- ane A 2 ...prevents ...
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Modulation of monocyte endothelial cell interactions by platelet microparticles
... produce microparticles (MP) from the plasma membrane, which are released into the extracellular ...that platelet-derived MP influence platelet and endothelial cell ...vein endothelial ...
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Evaluation of Endothelial and Platelet Derived Microparticles in Patients with Acute Coronary Syndrome
... of endothelial mono layer’s anticoagulant, antiplatelet and fibrinolytic ...During endothelial dysfunction, considerable cell damage occurs due to ...into: platelet microparticles ...
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Tissue Factor and Platelet Microparticles in Acute Myocardial Infarction
... that endothelial tissue factor microparticles and PMP peak-levels (at day 1) were significantly correlated with peak of high sensitive ...of microparticles in ACS patients may reflect a protective ...
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Platelet microparticles and hemostatic disturbances in renal insufficiency and cardiovascular disease
... vasodilation is measured at certain time points, and the relative change of the diameter of the artery is determined. The largest randomized controlled trials using vitamin D in CKD were the PRIMO trial (66) and the ...
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Circulating microparticles as biomarkers of stroke: A focus on the value of endothelial- and platelet-derived microparticles.
... of microparticles (MPs) from various cellular origins in the ...diseases. Endothelial activation and dysfunction and altered thrombotic responses are two of the main features predisposing to ...stroke. ...
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Platelet CD36 mediates interactions with endothelial cell–derived microparticles and contributes to thrombosis in mice
... cell-derived microparticles (MPs) are generated in response to vascular injury and circulate in patients with prothrombotic diseases, we hypothe- sized that PS exposed on their surfaces could be an endogenous CD36 ...
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Increased concentrations of platelet- and endothelial-derived microparticles in patients with myocardial infarction and reduced renal function- a descriptive study
... It is of importance to note that there was no difference in proportion of STEMI versus non STEMI in our three groups since previous papers reported that MP levels vary with type of AMI and infarction size [34, 35]. There ...
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An Overview on Platelet-derived Microparticles in Platelet Concentrates: blood collection, method preparation and storage
... the platelet product, which is not detected commonly used by routine blood count analyzers and are not routinely implemented by blood transfusion services and may needs to be considered as a quality marker for ...
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The Effect of Circular Training Program on Endothelial-Derived Microparticles in Overweight Men
... composition monitor (OMRON, Finland). The participants completed 8 weeks circular training, 3 times per weeks in consist of combined resistance and interval exercise in each exercise session. In each exercise session, ...
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An investigation into the relationship between platelet activation (platelet monocyte interaction & microparticles), inflammation and microvascular dysfunction in coronary artery disease
... with endothelial markers of the evolving plaque reveals a rich network of capillary vessels which develop in response to angiogenic factors (vascular endothelial growth factor [VEGF], placental growth ...
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Role of microparticles derived from monocytes, endothelial cells and platelets in the exacerbation of COPD
... only platelet poor plasma (PPP), while others also pellet the MPs before ...residual platelet contamination, and thus this fact may affect the final MP ...
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<p>Platelet-Derived Microparticles are an Important Biomarker in Patients with Cancer-Associated Thrombosis</p>
... on endothelial cells, enables protein C ...a platelet-related biomarker with procoagulant activity that contributes to thrombosis for- mation and ...
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Interferon-β1a reduces plasma CD31+ endothelial microparticles (CD31+EMP) in multiple sclerosis
... within four hours of blood collection to reduce nonspecific loss of EMP which we have found even when specimens are fro- zen at -70°C ...prepare platelet rich plasma ...obtain platelet-poor plasma ...
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Endothelial microparticles are increased in congenital heart diseases and contribute to endothelial dysfunction
... increase endothelial cell permeability and promote endothelial cell activation, dysfunction, and apoptosis [25, 26], our data suggests that EMPs may induce inflammation to impair endothe- lial function and ...
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A rapid flow cytometric technique for the detection of platelet monocyte complexes, activated platelets and platelet derived microparticles
... During platelet activation, anionic phospholipids are exposed to the platelet surface and PDM are formed creating a procoagulant surface. This is the matrix for the reaction of factor Xa, thrombin and ...
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Circulating Apoptotic Endothelial Cells and Apoptotic Endothelial Microparticles Independently Predict the Presence of Cardiac Allograft Vasculopathy
... and endothelial repair in a paracrine ...of endothelial repair that were evaluated in the current study are not suited for clinical prediction models of ...of endothelial repair discriminate between ...
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Vascular endothelial microparticles-incorporated microRNAs are altered in patients with diabetes mellitus
... Methods and results: Circulating MPs were isolated from 135 patients with or without diabetes mellitus type II and characterized using flow cytometer and electron microscope. Nine miRs involved in the regulation of ...
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Targeting the Monocytic-Endothelial-Platelet Axis with Maraviroc and Pravastatin as a
... CCR5 and fractalkine receptors on the S1 protein expressing CD16+ monocytes using maraviroc and pravastatin,. 390[r] ...
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Inhibition of platelet function by an aspirin insensitive endothelial cell ADPase Thromboregulation by endothelial cells
... of platelet-derived endoperoxides to prostacyclin by endothelial ...aspirin-treated endothelial cells, they remain unresponsive despite absence of ...prostacyclin. Platelet inhibition is due ...
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