ChAT, choline acetyltransferase
Pathological changes of distal motor neurons after complete spinal cord injury
... of ChAT (choline acetyltransferase), VAChT (cho- line vesicle transporter), and other choline-related transport molecules such as KIF3A, KIF3B, and KAP3 were increased in the Tx3m group ...
15
The absence of retinal input disrupts the development of cholinergic brainstem projections in the mouse dorsal lateral geniculate nucleus
... factor; ChAT: Choline acetyltransferase; CP: Cerebral peduncle; CTB: Cholera toxin subunit B; DL: Dorsolateral; dLGN: Dorsal lateral geniculate nucleus; DM: Dorsomedial; DSGC: Direction- selective ...
15
A scalable solution for isolating human multipotent clinical-grade neural stem cells from ES precursors
... monophosphate; CHAT: Choline acetyltransferase; CNS: Central nervous system; CoMo-NSC: hNSCs purified based on colony morphology; Cxcr4: C-X- C chemokine receptor type 4; DAB: Diaminobenzidine; ...
19
Neurogenic potential of dental pulp stem cells isolated from murine incisors
... variance; ChAT: choline acetyltransferase; CsGlutamine: caesium glutamine; Cx43: connexin 43; DAPI: 4 ’ ,6-diamidino-2-phenylindole; DPSC: dental pulp stem cell; (D)MEM: (Dulbecco ’ s) modified Eagle ...
13
Is aclidinium alone or combined with a LABA a rational choice for symptomatic COPD patients?
... test; ChAT: Choline acetyltransferase; CI: Confidence interval; COPD: Chronic obstructive pulmonary disease; CRISPLD2: Cysteine-rich secretory protein LCCL domain-containing 2; DALY: Disability ...
10
The neuroprotective effects of human bone marrow mesenchymal stem cells are dose-dependent in TNBS colitis
... ALS: Amyotrophic lateral sclerosis; BM: Bone marrow; ChAT: Choline acetyltransferase; DMSO: Dimethyl sulfoxide; FBS: Fetal bovine serum; ENS: Enteric nervous system; H&E: haematoxyli[r] ...
18
Neuroprotective effects of donepezil against cholinergic depletion
... ACh: Acetylcholine; AChE-I: Acetylcholinesterase inhibitor; AD: Alzheimer ’ s disease; ANOVA: Analysis of variance; AP: Anteroposterior; A β : Amyloid β ; ChAT: Choline acetyltransferase[r] ...
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The effect of nucleus basalis magnocellularis deep brain stimulation on memory function in a rat model of dementia
... Choline acetyltransferase (ChAT) immunohistochemistry After behavioral testing, three out of six rats from the normal group, three out of the seven rats from the lesion group, three out of seven rats ...
9
Co-expression of GAD67 and choline acetyltransferase in neurons in the mouse spinal cord: a focus on lamina X
... To determine the possible termination sites of the double la- belled ChAT/GAD67-IR cells, we performed immunohistochemistry for the vesicular acetylcholine transporter (VAChT) and GAD67. VAChT immunoreactivity was ...
10
Co-expression of GAD67 and choline acetyltransferase reveals a novel neuronal phenotype in the mouse medulla oblongata
... with choline acetyl transferase (ChAT) immunohistochemistry. ChAT-immunoreactive (IR) and GAD67-GFP containing neurones were observed throughout the ...both ChAT-IR and ...All ChAT-IR ...
9
Characterization of Human 82-kDa Choline Acetyltransferase expression in a newly developed Transgenic Mouse Model
... 82-kDa ChAT in these other tissues is required and will add to the current knowledge of ...82-kDa ChAT transgenic protein is localized to cholinergic ...high-affinity choline transporter (CHT), ...
121
12-11-2013 12:00 AM The role of choline acetyltransferase variants in Alzheimer's disease models
... kDa ChAT contains a basic region that is both necessary and sufficient for nuclear localization of the enzyme (Resendes et ...kDa ChAT and a small pool of 82-kDa ChAT is mediated through the ...
87
Concordance between in vivo and postmortem measurements of cholinergic denervation in rats using PET with [18F]FEOBV and choline acetyltransferase immunochemistry
... The cortical cholinergic denervation was estimated by optical density (OD), obtained from digitized images of the ChAT-immunostained sections. This work was car- ried out using Image-J (NIH Research Services ...
8
Bifurcation Analysis of a Coupled Acetylcholinesterase/Choline Acetyltransferase Enzymes Neurocycle
... Acetylcholine (ACh) serves as the transmitter of nerve impulses at cholinergic synapses. In humans and ho- moeothermic animals, it affects transmission from motor nerves to skeletal muscles, from preganglionic parasym- ...
20
CHOLINE ACETYLTRANSFERASE-DEFICIENT MUTANTS OF THE NEMATODE CAENORHABDITIS ELEGANS
... It would, therefore, appear that such selection schemes select for a narrow “window” of residual ChAT activity: the enzyme activity must be low enough to give resistan[r] ...
22
A Non-Canonical Role for Choline Acetyltransferase in Chromatin Organization and the Response to Beta-Amyloid
... 82-kDa choline acetyltransferase (82-kDa ChAT) protein and special AT-rich sequence binding protein 1 (SATB1) are associated with scaffolding/matrix attachment regions after neuronal cells were ...
262
Plans Toward Automated Chat Summarization
... tive, chat summarization is also applicable to other domains. For example, chat is used for communica- tion in multinational companies (Handel and Herb- sleb, 2002), open source meetings (Shihab et ...
7
Proton MR Spectroscopy for the Evaluation of Brain Injury in Asphyxiated, Term Neonates
... The second category also included only a single patient. This patient was abnormal in both neuro- logic and cognitive outcome despite normal lactate/ choline ratios on the MRS performed on the second day of life ...
7
Disentangling Chat
... We begin in Section 2 with an overview of related work. In Section 3, we present a new corpus of manually annotated chat room data and evaluate annotator reliability. We give a set of metrics (Section 3.2) ...
22
RF Chat
... Paper [4] is based on efficient utilization of communication links between RF Modems, which facilitate vehicle monitoring, vehicle authentication and automated toll collection on the highways over wireless channels. The ...
5