Checkpoint proteins
Contrasting Roles of Checkpoint Proteins as Recombination Modulators at Fob1-Ter Complexes with or without Fork Arrest
... of checkpoint proteins on recombination at ...replication checkpoint proteins of the adapter class on recombination provoked by fork arrest at ...adapter proteins, namely, Tof1 and ...
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Two Complexes of Spindle Checkpoint Proteins Containing Cdc20 and Mad2 Assemble during Mitosis Independently of the Kinetochore in Saccharomyces cerevisiae
... of checkpoint proteins that were assembled into complexes by size exclusion chromatog- ...of proteins present per yeast cell arrested in M ...the checkpoint proteins (Bub3, Mad2, and ...
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Original Article Correlation of CD8 infiltration and expression of its checkpoint proteins PD-L1 and PD-L2 with the stage of cervical carcinoma
... of checkpoint inhibitors in patients with invasive ...key checkpoint proteins, PD-L1 and PD-L2, varied between early stage (FIGO IA-IIA) and advanced stage (FIGO IIB-IVA) cervical ...
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Volkmer, Elias (2004): Human checkpoint proteins hRad9, hHus1, and hRad1 form a DNA damage-responsive complex. Dissertation, LMU München: Medizinische Fakultät
... of checkpoint research, for example for checkpoint- based ...G1-S checkpoint, which generally increases radiosensitivity of ...G1-S checkpoint (Powell et al., 1995). Selective G2- ...
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BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligands
... ligand proteins in vertebrates and yeast, and have characterised their specific interactions structurally and ...ligand proteins together into specific functional assemblies for DNA replication and ...
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Checkpoint Proteins Influence Telomeric Silencing and Length Maintenance in Budding Yeast
... constructed by PCR using, respectively, pFA6a-HIS3 and points have a role in telomere length maintenance. First, pFA6a-kanMX4 plasmids (Wach et al. 1994) as templates and in fission yeast, DNA replication ...
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Interactions of Claspin with replication and checkpoint proteins
... Xenopus homolog of Claspin and its functional interactions with DNA, chromatin, and other proteins (28). In the schematic in Figure 3.2A, we note a region termed the replication fork- interaction domain (RFID), ...
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Telomere Binding of Checkpoint Sensor and DNA Repair Proteins Contributes to Maintenance of Functional Fission Yeast Telomeres
... and checkpoint proteins: absence of Taz1 protein, telomeres cannot be main- In ...Rif2 proteins, is thought to be gene was deleted in cells that were already deleted for involved in negative ...
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The dynamic protein architecture of human kinetochores
... those proteins and other outer domain checkpoint proteins at the kinetochore until the proper time when they can be stripped by dynein (DeLuca et ...kinetochore proteins to localize could be a ...
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Contributions of DNA2 and the Tim/Tipin Complex to Genomic Stability
... maximal checkpoint activation (Ellison & Stillman, 2003; MacDougall et al, 2007; Shiotani & Zou, ...the checkpoint appears to be RPA-coated ssDNA, its real purpose may be to simply bring these three ...
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Spy1 Regulation of the DNA Damage Response; Checkpoint Activation and Cellular Senescence
... same proteins involved in the formation of γ-H2AX foci ...same proteins as DNA damage-induced breaks, repair mechanisms like non-homologous end joining (NHEJ) are able to join any two dysfunctional ...
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Study of Checkpoint Restore mechanism for Fault Tolerance in Cloud computing
... Koo-Toeg [4] proposed a minimum-process coordinated checkpointing protocol which relaxes the assumption that all communications are atomic. It reduces the number of synchronization messages and number of checkpoints. Cao ...
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Eichinger, Christian (2009): Coordination of synaptonemal complex formation and pachytene checkpoint signaling in meiosis. Dissertation, LMU München: Fakultät für Biologie
... pachytene checkpoint and the formation of ...pachytene checkpoint activation and SC ...the checkpoint kinase Mec1 at specific consensus sites is necessary for correct SC maturation (Carballo et ...
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The deubiquitinase USP44 is a tumor suppressor that protects against chromosome missegregation
... Mammalian heme transporters The identification and characterization of heme and other porphyrin transporters in mammals has proven to be difficult (2), in part due to a lack of genetic and molecular tools, but also as a ...
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Epigenetic Aberrant Hypermethylation of DNA in Endometrial Cancer: Application as a Biomarker
... We detected aberrant methylation of hMLH1 in 40.4% of cases of endometrial cancer, and similar aberrant me- thylation of APC, E-cadherin, and checkpoint with fork- head-associated and ring finger (CHFR) in 22.0%, ...
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Regulation of Histone Deposition Proteins Asf1/Hir1 by Multiple DNA Damage Checkpoint Kinases in Saccharomyces cerevisiae
... Hir proteins, and Asf1 are histone H3/H4 binding proteins important for chromatin-mediated transcriptional ...these proteins and S- phase/DNA damage checkpoint kinases in the budding yeast ...
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The Activation of ATR in Response to Double-Stranded DNA Breaks
... chromatin, checkpoint activation is mildly compromised in the absence of ...the checkpoint-activating template but more likely in close ...the checkpoint was not fully abrogated in the absence of ...
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Socioeconomic position Is associated with carotid intima media thickness in mid childhood: The longitudinal study of Australian children
... during CheckPoint, at age 11 to 12 ...smoking. CheckPoint indicates Child Health CheckPoint; IMT, intima – media thickness; LSAC, Longitudinal Study of Australian Children; SEP, socioeconomic ...
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Cataract Detection
... the checkpoint overhead and execution time of the ...the checkpoint placement of the dynamic interval pagelevel incremental Checkpointing is more efficient than any other periodic pagelevel incremental ...
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The centrosome orientation checkpoint is germline stem cell specific and operates prior to the spindle assembly checkpoint in Drosophila testis
... Mutant analysis of multiple centrosomal components in this study revealed a selective requirement for centrosomal components in the function of the COC. Sas-4 and Cnn are crucial for COC function, whereas Spd-2 and Apc1 ...
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