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chemopreventive agent

Prevalence of Nsaids (Non Steroidal Inflammatory Drugs) as a Chemopreventive Agent in Different Types of Cancer: Retrospective Detail Studies

Prevalence of Nsaids (Non Steroidal Inflammatory Drugs) as a Chemopreventive Agent in Different Types of Cancer: Retrospective Detail Studies

... a chemopreventive agent by different possible mechanism of ...The chemopreventive features of NSAIDs in case of brain tumor are still not approved and require further observational and experimental ...

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EVALUATION OF SELENIUM NANOPARTICLES AS A POTENTIAL CHEMOPREVENTIVE AGENT AGAINST LUNG CARCINOMA

EVALUATION OF SELENIUM NANOPARTICLES AS A POTENTIAL CHEMOPREVENTIVE AGENT AGAINST LUNG CARCINOMA

... The prospect of natural resources for metal nanoparticles synthesis has become to be a competent in the perspective of cost effective and eco-friendly points. Researchers prefer a biological synthesis because the ...

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Mitochondrial structure alteration in human prostate cancer cells upon initial interaction with a chemopreventive agent phenethyl isothiocyanate

Mitochondrial structure alteration in human prostate cancer cells upon initial interaction with a chemopreventive agent phenethyl isothiocyanate

... A disruption of mitochondrial membrane potential has described as an early event of the apoptosis process [30]. Mitochondrial membrane potential was examined by staining with a dye, JC-1, which forms a color aggregate ...

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Gallic Acid, a Promising Chemopreventive Agent, Antagonizes Breast Cancer: Molecular Mechanisms of Action from Cell Culture Studies

Gallic Acid, a Promising Chemopreventive Agent, Antagonizes Breast Cancer: Molecular Mechanisms of Action from Cell Culture Studies

... The present investigation was intended to gain an insight into the potency of gallic acid in targeting multiple molecules implicated in the signalling pathways of canc[r] ...

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In Vivo Application of Jania Rubens Silver Nanoparticles As A Chemopreventive Agent

In Vivo Application of Jania Rubens Silver Nanoparticles As A Chemopreventive Agent

... Our result showed that the treatment of gentamicin intoxicated rats with nanoparticles algae cause decreasing in serum creatinine, serum uric acid, and serum urea level due to[r] ...

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against melanoma cells: inhibition of metastasis and induction of cell-cycle arrest and apoptosis through modulation of Wnt/β-catenin signaling pathways

against melanoma cells: inhibition of metastasis and induction of cell-cycle arrest and apoptosis through modulation of Wnt/β-catenin signaling pathways

... cell death, characterized by a number of well-defined features, including cellular morphological changes, chromatin condensation, internucleosomal DNA cleavage and the activation of caspase cascades [47]. The death- ...

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Encapsulated nanoepigallocatechin-3-gallate and elemental selenium nanoparticles as paradigms for nanochemoprevention

Encapsulated nanoepigallocatechin-3-gallate and elemental selenium nanoparticles as paradigms for nanochemoprevention

... has chemopreventive effects, but its application is limited due to a low therapeutic index as shown in numerous animal ...promising chemopreventive agent without major toxicity ...superior ...

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Tamoxifen for women at high risk of breast cancer

Tamoxifen for women at high risk of breast cancer

... The National Surgical Adjuvant Breast and Bowel Project (NSABP) Breast Cancer Prevention Trial was designed to observe the effectiveness of tamoxifen as a chemopreventive agent in high-risk women. ...

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Anticancer effects of clinacanthus nutans crude extracts in cervical cancer cells

Anticancer effects of clinacanthus nutans crude extracts in cervical cancer cells

... 20 μg/mL which is the allowed dosed fixed by the National Cancer Institute (NCI) for potential anticancer drug. The cytotoxic effect of this herb towards cervical cancer cell line such as HeLa has made it as a potential ...

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  ANTIOXIDANT AND ANTI-INFLAMMATORY PROPERTIES OF ETHANOLIC EXTRACT OF LAVANDULA STOECHAS L. FROM TAOUNATE REGION IN MOROCCO

  ANTIOXIDANT AND ANTI-INFLAMMATORY PROPERTIES OF ETHANOLIC EXTRACT OF LAVANDULA STOECHAS L. FROM TAOUNATE REGION IN MOROCCO

... a chemopreventive agent, providing antioxidant properties and offering effective protection from free radicals, and confirm the Moroccan traditional use of this plant for the treatment of inflammatory ...

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Chemopreventive activity of sulforaphane

Chemopreventive activity of sulforaphane

... nontoxic chemopreventive agent, and exerts anticancer activities through multiple mechanisms, including regulation of Phase I and Phase II DMEs, anti-inflammatory activity, cell cycle arrest, induction of ...

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Dietary pterostilbene is a novel MTA1-targeted chemopreventive and therapeutic agent in prostate cancer

Dietary pterostilbene is a novel MTA1-targeted chemopreventive and therapeutic agent in prostate cancer

... Since there is a direct relationship between MTA1 and Akt (Figure 1B and 1C and Figure 2A and 2B), pterostilbene prevents the activation of Akt pathway, at least in part, by targeting MTA1 and thereby decreasing MTA1 ...

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ROLE OF CHEMOPREVENTION IN CANCERS

ROLE OF CHEMOPREVENTION IN CANCERS

... Oral cancer causes considerable morbidity and is associated with a 5-year survival rate of less than 50%. It is a major problem in populations in which alcohol and tobacco use are prevalent such as in lower socioeconomic ...

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DIETARY PHYTOCHEMICALS AND THEIR ROLE IN CHEMOPREVENTION OF CANCER

DIETARY PHYTOCHEMICALS AND THEIR ROLE IN CHEMOPREVENTION OF CANCER

... Crocetin from saffron: Saffron is a spice from the flower of the Saffron crocus and a food colorant present in the dry stigmas of the plant Crocus sativus L. Saffron is reported as a potential agent for a novel ...

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Phytochemicals of Nutraceutical Importance: Their Role In Health and Diseases

Phytochemicals of Nutraceutical Importance: Their Role In Health and Diseases

... antispasmodic, chemopreventive, hepatoprotective, hypolipidemic, neuroprotective, hypotensive, prevent aging, diabetes, osteoporosis, cancer and heart diseases, induce apoptosis, diuretic, CNS stimulant, ...

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A BRIEF PHYTOCHEMICAL INVESTIGATION AND PHARMACOLOGICAL USES OF CITRUS SEED – A REVIEW

A BRIEF PHYTOCHEMICAL INVESTIGATION AND PHARMACOLOGICAL USES OF CITRUS SEED – A REVIEW

... According to Naunyn-Schmiedeberg's Arch Pharmacol (2014) C. aurantium var. bigardia derived limonin is effective as hepatoprotective agent in hepatic injury. We have experimented the effects of limonin in two dose ...

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Resveratrol and Quercetin: Novel Polyphenolic  Chemopreventive Agents

Resveratrol and Quercetin: Novel Polyphenolic Chemopreventive Agents

... Quercetin inhibits heat shock protein induction but not heat shock factor DNA-binding in human breast carcinoma cells. Elia G, Amici G, Rossi A et al[r] ...

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Evaluation of the antifungal activities of various extracts from Pistacia atlantica Desf

Evaluation of the antifungal activities of various extracts from Pistacia atlantica Desf

... The crude powder of miconazole (MZ) as the control agent was purchased from Sigma- Aldrich, St Louis, MO, USA. RPMI-1640 medium, l-glutamine and Sabouraud dextrose agar (SDA) were purchased from Sigma- Aldrich Co. ...

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Petrick_unc_0153D_14481.pdf

Petrick_unc_0153D_14481.pdf

... The rationale for considering flavonoid intake as a potential chemopreventive is supported by evidence from population and laboratory research. Epidemiological studies have shown that [r] ...

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TINOSPORA CORDIFOLIA: ETHNOBOTANY, PHYTOPHARMACOLOGY AND PHYTOCHEMISTRY ASPECTS

TINOSPORA CORDIFOLIA: ETHNOBOTANY, PHYTOPHARMACOLOGY AND PHYTOCHEMISTRY ASPECTS

... Chemopreventive potential of a medicinal plant Tinospora cordifolia on skin carcinogenesis in mice.. J Environ Pathol Toxicol Oncol.[r] ...

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