Chemoradiotherapy regimen and Surgery
Esophageal Cancer : Neoadjuvant chemoradiotherapy and surgery
... plus surgery or surgery ...to surgery, but these studies used different nCRT regimens and were criticized because of the potential influence of selection bias and lack of statistical ...plus ...
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CHEMORADIOTHERAPY PLUS SURGERY FOR GASTRIC ADENOCARCINOMA
... Exclusion of the splenic nodes was allowed in patients with antral lesions if it was necessary to spare the left kidney. Radiation was delivered with at least 4-MV photons. Doses were limited so that less than 60 percent ...
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High-dose chemoradiotherapy followed by surgery versus surgery alone in esophageal cancer: a retrospective cohort study
... concomitant chemoradiotherapy (CRT), whereas others have not found any survival benefit by preoperative CRT over surgery alone ...after surgery alone and after CRT followed by ...motherapy ...
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CRITICS-II: a multicentre randomised phase II trial of neo-adjuvant chemotherapy followed by surgery versus neo-adjuvant chemotherapy and subsequent chemoradiotherapy followed by surgery versus neo-adjuvant chemoradiotherapy followed by surgery in resectable gastric cancer
... CT regimen used in the CRITCS-II trial is a slight variation of FLOT, and the results of the FLOT4-AIO study support the use of DOC as preopera- tive CT in our ...
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Comparison of the prognosis of neoadjuvant chemoradiotherapy treatment with surgery alone in esophageal carcinoma: a meta-analysis
... our regimen might be adequate for a benefit in patients with squamous cell car- cinoma; however, we cannot conclude this possibility with certainty on the basis of the subgroup ...
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Outcomes of preoperative chemoradiotherapy followed by surgery in patients with unresectable locally advanced sigmoid colon cancer
... We recognize that our study has some limitations. First, the sample size was small and the median follow-up period of 42 months was rather short. Second, the radia- tion technique/dose and the chemotherapy regimen ...
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Definitive Chemoradiotherapy Versus Surgery Followed by Adjuvant Radiotherapy in Resectable Stage III/IV Hypopharyngeal Cancer
... upfront surgery followed by adjuvant RT (SRT group), and 34 patients were treated with definitive chemoradiotherapy (CRT ...radical surgery followed by RT (n=41) or concurrent CRT (n=16). Types of ...
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External Validation of Pretreatment Pathological Tumor Extent in Patients with Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal Cancer
... Clinical staging consisted of a standardized preoperative work-up, including endoscopy with histological biopsy, endoscopic ultrasonography (EUS), and thoracic and abdominal computed tomography (CT). Clinical T and N ...
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Surgery with versus without preoperative concurrent chemoradiotherapy for mid/low rectal cancer: an interim analysis of a prospective, randomized trial
... The most likely explanation for the similarities between the two groups in our study is that oxaliplatin may not be a clinically effective radiation sensitizer. Based on its suc- cessful use in colorectal cancer, ...
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Original Article Short-course radiotherapy with delayed surgery versus conventional chemoradiotherapy: comparison of short-term outcomes in patients with T
... delayed surgery (SRT-delay) and a standard conventional chemoradiotherapy (CRT) ...SRT-delay regimen and 98 patients were treated using the CRT ...SRT-delay regimen was not inferior in terms ...
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Lymph Node Harvest in Rectal Cancer Surgery Following Neoadjuvant Chemoradiotherapy
... curative surgery from 2009 through 2012 at a single District General Hospital in the United Kingdom were included in the ...course chemoradiotherapy if they were stage II or ...in surgery group, ...
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High dose chemoradiotherapy followed by surgery versus surgery alone in esophageal cancer: a retrospective cohort study
... Methods: Hundred-and-seven patients with disease stage IIA - III were treated with either surgery alone (n = 45) or high-dose preoperative CRT (n = 62). The data were collected retrospectively. Sixty-seven ...
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Primary surgery versus chemoradiotherapy for advanced oropharyngeal cancers: a longitudinal population study
... Daniel O ’ Connell 1 , Hadi Seikaly 1* , Russell Murphy 1 , Charles Fung 2 , Tim Cooper 2 , Aaron Knox 2 , Rufus Scrimger 3 and Jeffrey R Harris 1,4* Abstract Background: Treatment for advanced stage oropharyngeal ...
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The role of definitive chemoradiotherapy versus surgery as initial treatments for potentially resectable esophageal carcinoma
... 6. Urba SG, Orringer MB, Turrisi A, Iannettoni M, Forastiere A, Strawderman M. Randomized trial of preoperative chemoradiation versus surgery alone in patients with locoregional esophageal carcinoma. J Clin Oncol. ...
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Meta-analysis of postoperative efficacy in patients receiving chemoradiotherapy followed by surgery for resectable esophageal carcinoma
... This finding may contribute to better survival outcomes and lower postoperative mortality. There was evidence that patients treated with SA were more likely to undergo the scheduled surgery. However, the rate of ...
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Outcome and prognostic factors in cervical cancer patients treated with surgery and concurrent chemoradiotherapy: a retrospective study
... 24. Wakayama A, Inamine M, Kudaka W, Nagai Y, Nakamoto T, Ooyama T, et al. Concurrent chemoradiotherapy for non-bulky stage IB/II cervical cancer without pelvic node enlargement. Anticancer Res. 2013;33:5123 – 6. ...
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Treatment Interval between Neoadjuvant Chemoradiotherapy and Surgery in Rectal Cancer Patients: A Population-Based Study
... In addition to various important factors such as tumor stage, histology, and CRM, 20 tumor response has been recognized as an important predictor of local recurrence and OS in rectal cancer surgery. 21 It has ...
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Treatment Interval between Neoadjuvant Chemoradiotherapy and Surgery in Rectal Cancer Patients: A Population-Based Study
... In addition to various important factors such as tumor stage, histology, and CRM, 20 tumor response has been recognized as an important predictor of local recurrence and OS in rectal cancer surgery. 21 It has ...
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Review Article Standard and restrictive fluid regimen in major abdominal surgery: a meta-analysis of RCTs
... However, RFR increased the risk of postopera- tive renal dysfunction (RR: 1.49, P = 0.02). The kidney has large blood flow volumes with the physiological function of regulating systemic liquid volumes and is sensitive to ...
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Neoadjuvant chemoradiotherapy followed by surgery in patients with unresectable locally advanced colon cancer: a prospective observational study
... The reasons of unresectability mainly included the follow- ing: 1) preoperative imaging examinations showed that the tumor extensively invaded into the adjacent organs, such as the bladder, ureter, small intestine, ...
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