Chitosan, Drug Delivery
Degradability of chitosan micro/nanoparticles for pulmonary drug delivery
... nanoparticulate drug delivery is progressing and has achieved remarkable outcomes, but there are many challenges such as the biodegradability and possible toxicity of nanoparticles in biolog- ical systems ...
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Chitosan Microspheres in Novel Drug Delivery Systems
... cosmetics, drug delivery and many other medical and pharmaceutical ...biodegradability chitosan is really an attractive biopolymer for delivering a wide variety of drugs in a controlled/sustained ...
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Preparation and Characterization of Novel Drug Inserted Montmorillonite Chitosan Carriers for Ocular Drug Delivery
... of drug-loaded nanoparticles for prolonged ocular ...of chitosan with sodium tripolyphosphate ...of drug-encapsulated chitosan-montmorillonite/TPP nanoparticles (CS-MMT/TPP ...sustained ...
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Hydrophobically modified chitosan nanoliposomes for intestinal drug delivery
... modified chitosan derivative and utilize this to formu- late liposomes for oral drug delivery, using iron sulfate as a model hydrophilic ...this chitosan derivative retains the characteristic ...
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PHARAMACEUTICAL RELEVANCE OF CROSSLINKED CHITOSAN IN MICROPARTICULATE DRUG DELIVERY
... injectable-chitosan-based delivery system with low cytotoxicity was fabricated by using genipin and glutaraldehyde as cross-linking ...genipin-cross-linked chitosan microspheres injected ...
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A REVIEW ON CHITOSAN-BASED HYDROGLES FOR THE DRUG DELIVERY SYSTEM
... release drug delivery applications ...preparing drug delivery ...oral delivery of protein ...protein drug delivery. The adsorption of bovine serum albumin in ...
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A Review on Chitosan Based Nanoparticle as a New Ocular Drug Delivery
... the drug to release in a sustained mode of drug delivery and would slowly release the drug particles from the ...the drug is released too slowly or too fast then there is a possibility ...
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CHITOSAN LOADED MICROSPHERES OF TROPICAMIDE AS CONTROLLED RELEASE OF DRUG FOR OCULAR DRUG DELIVERY SYSTEM
... the drug residence time due to the capacity to adhere at mucin coat covering the conjunctiva and the corneal surfaces of the eye by non-covalent bonds forming the basis of ocular ...mucoadhesion. Chitosan ...
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Anticancer drug delivery with transferrin targeted polymeric chitosan vesicles
... N-palmitoylglucosamine (2) and palmitoyl glycol chito- san (11) were synthesized and characterized as previously de- scribed. Doxorubicin hydrochloride (Dox) was supplied by Alexis Biochemicals (UK). Glycol ...
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Factors determining the stability, size distribution, and cellular accumulation of small, monodisperse chitosan nanoparticles as candidate vectors for anticancer drug delivery: application to the passive encapsulation of [<sup>14</sup>C]-doxorubicin
... distributed chitosan nanoparticles (CNPs) with diameters as small as 62 nm and a polydispersity index (PDI) of ...the chitosan polymer with sodium ...
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Preparation, characterization, and potential application of chitosan, chitosan derivatives, and chitosan metal nanoparticles in pharmaceutical drug delivery
... delivery of any therapeutic agent, either into the skin strata regarding topical application or into the systemic circulation through transdermal application. This barrier function is mainly due to the stratum ...
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<p>ROS-Responsive Chitosan Coated Magnetic Iron Oxide Nanoparticles as Potential Vehicles for Targeted Drug Delivery in Cancer Therapy</p>
... cationic polymer used to prepare nanoparticles by means of electrostatic interactions. 5- fl uorouracil (5-FU) is a hydrophilic drug. Two ionic interactions exist in the reac- tion process: an intense electrostatic ...
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Functional intercalated nanocomposites with chitosan-glutathione-glycylsarcosine and layered double hydroxides for topical ocular drug delivery
... Materials and methods: CG-GS-LDH intercalated nanocomposites were prepared by the coprecipitation hydrothermal method. In vivo precorneal retention study, ex vivo fluorescence images, in vivo experiment for distribution ...
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Utilization of MMT Clay and MMT Chitosan for Platinol Drug Delivery
... The montmorillonite clay (MMT) with cation exchange capacity (CEC) 90 meq per 100 g was supplied by Süd –Chemie-Moosburg- Germany. Chitosan (CS) with medium molecular weight (92.700 g/mol) and deacetylation degree ...
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Chitosan: introduction and its role as a drug delivery vehicle
... in Drug Targeting Systems. Due to the less toxicity of chitosan it does not cause any biological hazard and are inexpensive, these polymers might be suitable for use in the preparation of dosage forms of ...
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CHITOSAN NANOPARTICLE FOR DRUG DELIVERY A MINI REVIEW
... make chitosan a good candidate for the development of conventional and novel drug delivery ...unique drug delivery systems will be a significant value to current cancer ...on ...
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A REVIEW: MICRO CARRIER AS COLON DRUG DELIVERY SYSTEM
... Microspheres are small spherical particles, with diameters in the micrometer range (typically 1 μmto 1000 μm). Microspheres are sometimes referred to as micro particles. Microspheres can bemanufactured from various ...
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Corneal permeation properties of a charged lipid nanoparticle carrier containing dexamethasone
... L/NP-based drug delivery systems can alter the dynamics of intraocular ...the delivery of dexamethasone – a drug used in the treatment of ocular fundus diseases such as macular disease – ...
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Synthesis and Characterization of Chitosan/Cloisite 30B(MMT) Nanocomposite for Controlled Release of Anticancer Drug Curcumin
... the drug delivery system (DDS) concept is not new, great progress has recently been made in the treatment of a variety of ...Targeting delivery of drugs to the diseased lesions is one of the most ...
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FORMULATION DEVELOPMENT AND EVALUATION OF FLOATING MICROSPHERE OF TRAZODONE HYDROCHLORIDE
... then drug was added to chitosan ...of chitosan –drug solution through a disposable syringe (10 ml) onto a gently stirrer (100 rpm) at room temperature in 5% or 10% wt/vol (Sodium ...
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