Cholesterol Absorption
The relation between cholesterol absorption and cholesterol synthesis in the baboon
... total cholesterol production rates, cholesterol absorption, and total endogenous cholesterol synthesis have been measured in these animals by a double isotope technique in which the animals ...
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Cholesterol absorption status and fasting plasma cholesterol are modulated by the microsomal triacylglycerol transfer protein −493 G/T polymorphism and the usual diet in women
... the cholesterol absorption status and the metabolic response of women to a low-saturated fat, low-cholesterol/Mediterranean-type diet (LFLCD) 3-mo ...both cholesterol absorption markers ...
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Role of the ABCG8 19H risk allele in cholesterol absorption and gallstone disease
... esterol absorption irrespective of the presence or absence of gallstones and the polymorphism did not affect intes- tinal ABCG8 ...terol absorption as well ...of cholesterol secreted into intestine ...
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Bisphenol A promotes cholesterol absorption in Caco-2 cells by up-regulation of NPC1L1 expression
... for cholesterol absorp- tion ...intestinal cholesterol absorption and the processes of cholesterol homeostasis, we argued that BPA may directly influence its ...in cholesterol ...
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Hepatic nuclear corepressor 1 regulates cholesterol absorption through a TRβ1 governed pathway
... on cholesterol metabolism open a new avenue for therapeutic strategies with a potential to combine advantageous effects of activation of mul- tiple NR, including TR and ...
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Targeted disruption of the murine cholecystokinin 1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis
... dietary cholesterol or cholic acid (36), such an alteration could only be induced by fatty acids derived from digestion of dietary triglycerides in the lithogenic ...enhances cholesterol absorption ...
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Original Article Abnormality of intestinal cholesterol absorption in Apc Min/+ mice with colon cancer cachexia
... cholesterol absorption processes in the enterocytes of mouse. The main cholesterol importer NPC1L1 and the cholesterol exporters ABCG5/G8 are located at the apical membrane of enterocytes and ...
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Mapping a gene involved in regulating dietary cholesterol absorption The sitosterolemia locus is found at chromosome 2p21
... etary cholesterol retained in the body as well as the body’s ability to selectively exclude other dietary sterols are poorly ...both cholesterol and plant sterols from the ...dietary cholesterol ...
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An inhibitor of cholesterol absorption displays anti-myeloma activity by targeting the JAK2-STAT3 signaling pathway
... The activated JAK2-STAT3 signaling pathway is a high risk factor for multiple myeloma (MM), a fatal malignancy of plasma cells. In the present study, SC09, a potential inhibitor of cholesterol absorption, ...
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The pivotal role of cholesterol absorption inhibitors in the management of dyslipidemia
... Ezetimibe is the first clinically approved cholesterol absorption inhibitor. It is effective in lowering LDL-C as monotherapy or in combination with statins. The use of combination LDL-C lowering medication ...
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Regulation of Intestinal Cholesterol Absorption: A Disease Perspective
... intestinal cholesterol transporters using genetically modified animal ...the cholesterol absorption from the intestinal lumen such as NPC1L1 [32] and the ATP-binding cassette proteins ABCG5 and ABCG8 ...
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Dietary cholesterol and downregulation of cholesterol 7 alpha hydroxylase and cholesterol absorption in African green monkeys
... intestinal cholesterol absorption as potential regulatory sites responsive to dietary ...a cholesterol and fat-enriched diet was then fed for 12 wk during period 2, and finally, after a washout ...
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Intestinal cholesterol absorption efficiency in man is related to apoprotein E phenotype
... more cholesterol than those with the phenotype E4/3 and E4/4, the values for the individuals with the most frequent phenotype E3/3 (56% of the population sample) falling in ...
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STUDIES ON INTESTINAL CHOLESTEROL ABSORPTION IN THE HUMAN
... The total amount of endogenous cholesterol secreted during the digestion of a test meal was calculated from the dilution of the dietary cholesterol and the amount of test meal present in[r] ...
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DIRECT MEASUREMENT OF CHOLESTEROL ABSORPTION VIA THE THORACIC DUCT IN MAN
... However, in hyperlipemic subjects, the same ratio was 1.6 to 2.5.1 If it were assumed that all of the labeled ester and free cholesterol absorbed in lymph were retained in the plasma and[r] ...
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A Newly Integrated Model for Intestinal Cholesterol Absorption and Efflux Infers How Plant Sterol Intake Reduces Circulating Cholesterol Levels
... BBM and lumen promotes cholesterol efflux, and plant sterol in the BBM may disturb the trafficking 25.. machineries that transport cholesterol to the cell interior.[r] ...
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Molecular processes that handle — and mishandle — dietary lipids
... intestinal cholesterol absorption, decreased expression of Npc1l1 (28) and decreased hepatic biliary cholesterol excretion, and increased intestinal expression of ABCG5/G8 (28–30) cholesterol ...
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Effects of ezetimibe on cholesterol metabolism in HIV infected patients with protease inhibitor associated dyslipidemia: a single arm intervention trial
... terol absorption markers and an increase in cholesterol synthesis markers, which were in the range of the changes reported in non-HIV dyslipidemic subjects [15,17,18], sug- gesting that PI-containing ART ...
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Influence of Flaxseed on Some Biochemical Factors, Antioxidant Activity and Expression of ABCG5 and ABCG8 Genes in the Liver of Diabetic Rat
... of cholesterol is controlled by a several ways including: intestinal absorption, de novo synthesis, biliary clearance and also faecal elimination of ...of cholesterol elimination ...reduced ...
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“Azetidinones: An Overview” by Subin Mary Zachariah, Mridula Ramkumar, Namy George, Mohammad Salam Ashif, India.
... Azetidinones is a four member heterocyclic ring system with nitrogen as the hetero atom and a carbonyl group incorporated into it. It is also known as β-lactams. It shows a wide spectrum activity against gram +ve or gram ...
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