cholesterol homeostasis
Effect of neonatal modulation of cholesterol homeostasis on subsequent response to cholesterol challenge in adult guinea pig
... dietary cholesterol in adulthood can be modulated by the manipulation of cholesterol homeostasis during neonatal ...enhancing cholesterol degradation (cholestyramine feeding), high dietary ...
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Abnormal vascularization in mouse retina with dysregulated retinal cholesterol homeostasis
... retinal cholesterol homeostasis, including unexpected upregulation of retinal cholesterol ...by cholesterol deposition beneath the retinal pigment ...
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Altered Cholesterol Homeostasis in Aged Macrophages Linked to Neovascular Macular Degeneration
... that cholesterol homeostasis via ABCA1 in aging macrophages is important for ...targeting cholesterol trafficking in inflammatory cells in ...
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Do oxysterols control cholesterol homeostasis?
... hydroxylates cholesterol to yield 24S- hydroxycholesterol (10, 14). Unlike cholesterol, this oxysterol can pass the blood-brain ...of cholesterol, suggesting that there is a balance between synthesis ...
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Heterogeneity of cholesterol homeostasis in man Response to changes in dietary fat quality and cholesterol quantity
... and cholesterol on cholesterol homeostasis in ...dietary cholesterol. Dietary fat and cholesterol intakes, plasma lipid and lipoprotein levels, cholesterol absorption and sterol ...
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Pioglitazone prevents cholesterol gallstone formation through the regulation of cholesterol homeostasis in guinea pigs with a lithogenic diet
... pedite cholesterol efflux in the intestine and ...to cholesterol gallstone formation than wild-type mice when fed with a lithogenic diet ...to cholesterol gallstone formation, with a potent FXR ...
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The hepatokine Tsukushi is released in response to NAFLD and impacts cholesterol homeostasis
... How TSK controls cholesterol homeostasis is an important question. Here, we show that hepatic TSK acutely modulates gene expression in the liver, indicating that TSK acts at least via an autocrine and/or ...
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Hepatitis C Virus Replication Depends on Endosomal Cholesterol Homeostasis
... endosomal cholesterol homeostasis and cholesterol transport, requiring multiple cel- lular factors ...for cholesterol transport to DMVs is OSBP most likely delivering cholesterol in ...
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The intestinal microbiota regulates host cholesterol homeostasis
... In order to identify bacterial species or taxa involved in the regulation of cholesterol homeostasis, we ana- lyzed by 16S rRNA gene sequencing of the V3-V4 re- gion the fecal microbiota of recipient mice 9 ...
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Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice
... of cholesterol and lipid metabolism, and their activation has been shown to inhibit cardiovascular disease and reduce atherosclerosis in animal ...reverse cholesterol transport, cholesterol ...
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Dual functions of Insig proteins in cholesterol homeostasis
... The ER enzyme HMG-CoA reductase produces mevalonate, which is converted to sterols and to other products, including geranylgeraniol groups attached to proteins [64]. Similar to other proteins of the mevalonate pathway ...
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The influence of biological sex and sex hormones on bile acid synthesis and cholesterol homeostasis
... Sex differences in the therapeutic response to com- pounds that target BA synthesis may vary significantly not only with respect to the CYPs that mediate drug metabol- ism but also in the CYPs that regulate BA ...
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Disruption of cholesterol homeostasis by plant sterols
... perturbs cholesterol homeostasis in the adrenal ...in cholesterol content. Despite the very low cholesterol levels, there was no compensatory increase in cholesterol synthesis or in ...
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Age-associated alterations in cholesterol homeostasis: evidence from a cross-sectional study in a Northern Italy population
... of cholesterol homeostasis, were analyzed by gas chromatography–mass spectrometry, including lathosterol (synthesis), campesterol and sitosterol (absorption), and 7α-hydroxy-4-cholesten-3-one (degradation ...
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Effect of dietary eicosapentaenoic and docosahexaenoic acid on expression of rat liver genes controlling cholesterol homeostasis and on plasma cholesterol level
... Gene expression. Actb gene was used as an en- dogenous control in quantitative real-time PCR in the present study based on the results of the similar experiments measuring an effect of dietary PUFA n-3 on expression of ...
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Cholesterol and ocular pathologies: focus on the role of cholesterol-24S-hydroxylase in cholesterol homeostasis
... cluding cholesterol and cholesteryl esters, in BrM is a hall- mark of aging and AMD in humans (Curcio et ...2010). Cholesterol is the main sterol in the ...nerve. Cholesterol is provided to the ...
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Citrobacter rodentium Subverts ATP Flux and Cholesterol Homeostasis in Intestinal Epithelial Cells In Vivo.
... of cholesterol biosyn- thesis the cholesterol efflux transporters Abca1 and Abcg8 were also present at higher abundance in infected ...fecal cholesterol was detected in ...serum cholesterol ...
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Liver X Receptors and their Agonists: Targeting for Cholesterol Homeostasis and Cardiovascular Diseases
... of cholesterol and certain bile acids, such as 22(R)- hydroxycholesterol (22R-OHC), 20(S)-hydroxy- cholesterol (20S-OHC), 24(S)-hydroxy- cholesterol (24S-OHC), 25-hydroxycholesterol (25-OHC), ...
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Cholesterol Homeostasis: Lipoproteins In Action
... The cholesterol efflux mediated by SR-B1 is the primary event for HDL mediated metabolism of cholesterol in the ...of cholesterol from the cell surface as well as the delivery for excretion of ...
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Lipoproteins, cholesterol homeostasis and cardiac health
... The principal protein components of HDL are dual apolipoprotein (Apo) A1 peptides, which wrap around the particle in an anti-parallel, double-belt structure (7). Secondary structure of ApoA1 consists of ten transmembrane ...
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