chow fed
Atherogenesis and metabolic dysregulation in LDL receptor–knockout rats
... rats fed a ...rats fed WD, such that after 52 weeks, the plasma triglyceride levels were 4-fold higher in the KO than WT rats (Figure ...normal chow-fed KO rats, WD-fed KO rats ...
16
The effects of diet-induced obesity on hepatocyte insulin signaling pathways and induction of non-alcoholic liver damage
... their chow-fed counterparts. At the end of the study, untreated diet-fed (vehicle) animals were significantly heavier than chow-fed, diet-to-chow and fenofibrate-treated animals, ...
9
Ketogenesis prevents diet induced fatty liver injury and hyperglycemia
... in chow-fed adult mice caused mild hyperglycemia, increased hepatic gluconeogenesis from pyruvate, and augmented production of hundreds of hepatic metabolites, a suite of which indicated activation of the ...
17
High-Fat Diet Changes Fungal Microbiomes and Interkingdom Relationships in the Murine Gut
... Mice fed a high-fat diet had significantly different abundances of 19 bacterial and 6 fun- gal taxa than did mice fed standard chow, with high-fat diet causing similar magni- tudes of change in ...
14
Isolation and characterization of hepatic Golgi lipoproteins from hypercholesterolemic rats
... Table IV presents the fatty acid composition of the dietary triglycerides, and cholesteryl esters and triglycerides of nascent lipoproteins from chow-fed control and HC rats.. In both co[r] ...
12
Effects of diet-induced obesity on protein expression in insulin signaling pathways of skeletal muscle in male Wistar rats
... the chow-fed group, PKC- β expression was significantly increased in the vehicle (113%, P , ...the chow-fed controls (Figure ...the chow-fed control group (Figure ...
10
Impaired kisspeptin signaling decreases metabolism and promotes glucose intolerance and obesity
... standard chow, HFD-fed GDX Kiss1r KO males displayed no difference in BW compared with HFD-fed GDX WT males (Figure 3H), and their fat mass was also not dif- ferent (data not ...mice fed stan- ...
6
Increased plasma lipid levels exacerbate muscle pathology in the mdx mouse model of Duchenne muscular dystrophy
... when fed a chow or Western ...when fed a Western diet, total gastrocnemius muscle area from 7-month-old mdx -ApoE mice was sig- nificantly decreased compared to WT and ApoE controls ...S4A–D). ...
14
Sexually dimorphic metabolic responses mediated by CRF2 receptor during nutritional stress in mice
... vs. chow. (b) HFD-fed WT and Crhr2 −/− male mice increased their mesenteric fat depots by ...WT chow-fed controls, whereas Crhr2+/ − mice showed non-significant increases in mesenteric fat ...
16
Citrus polymethoxyflavones attenuate metabolic syndrome by regulating gut microbiome and amino acid metabolism
... mice. Chow-fed mice were treated daily with solvent ...from Chow, HFD, and PMFE ...in chow-fed mice was altered by HFD and then regulated by ...the Chow versus HFD and HFD versus ...
14
PPARγ deacetylation dissociates thiazolidinedione’s metabolic benefits from its adverse effects
... Interestingly, unlike the increased bone density in Pparg+/– heterozygotes 28, marrow adiposity was not different under basal conditions chow- or HFD-fed, untreated or vehicle-treated an[r] ...
14
Conditioned Place Preference Deficits in Adulthood Following High Fat and High Sugar Diet Intake in Pre and Periadolescence: A Test of the Specificity Hypothesis
... at least as much as in the Chow groups. Still, rats could have expressed “liking” (i.e., it was palatable), but not “wanting” (i.e., sought it less) for the US foods [29,30]. However, rats in each group moved ...
8
DNA methyltransferase inhibition restores erythropoietin production in fibrotic murine kidneys
... mice fed a regular one-half inch pellet diet of LabDiet 5001 (TestDiet) containing ...Mice fed a regular pellet diet (LabDiet 5001) served as ...mice fed a regular diet with or with- out ...
12
Key words
... France) intraperitoneally at a dose of 60 mg/kg. The neck and abdominal regions were shaved with a hair clipper (WAHL Clipper Corporation, USA). A small area of the skin around the ventral neck region was cut and a blunt ...
10
Reduction of atherosclerosis by administration of dehydroepiandrosterone A study in the hypercholesterolemic New Zealand white rabbit with aortic intimal injury
... cardiovascular disease. Like cancer, atherosclerosis is a proliferative process characterized by both initiation and promotion phases. This similarity provided a framework in which to study the antiatherogenic effects of ...
10
Neuronal GLP1R mediates liraglutide’s anorectic but not glucose lowering effect
... tolerance in high-fat–fed rats (6), but this may have been secondary to weight gain. The portal vein, which is innervated by the nodose ganglia and robustly expresses GLP1R, has also been hypothesized to ...
9
Modulation of the sympathetic nervous system by renal denervation prevents reduction of aortic distensibility in atherosclerosis prone ApoE deficient rats
... onstrated decreased aortic distensibility, associated with an increased aortic collagen content. This structural alteration was inhibited by RDN, preserving aortic dis- tensibility, and emphasizes the influence of the ...
11
Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2–dependent fibrinolysis
... The present study shows that, while levels of total lung A2 did not differ between normo- and hyperhomocysteinemic mice, the TPA- binding ability of A2 from hyperhomocysteinemic lungs was dra- matically diminished ...
12
An apolipoprotein E synthetic peptide targets to lipoproteins in plasma and mediates both cellular lipoprotein interactions in vitro and acute clearance of cholesterol rich lipoproteins in vivo
... peripheral tissues and the liver (1). ApoE is found predomi- nately in plasma in partially catabolized remnants of lipopro- teins that carry either dietary cholesterol (chylomicrons) or liver-derived cholesterol (VLDL). ...
13
Gut Microbiota Dysbiosis and Their Impact on Biochemical and Inflammatory Profiles in Cafeteria Diet Fed Sprague Dawley Rats
... Several studies have shown altered composition of the gut microbiota in the context of obesity in human and rodents and they conclude that all of these changes could contribute to the metabolic diseases. In our study, ...
15