Chromatin Architecture
Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease
... altered chromatin architecture, reduced HSF1 binding, and impaired HSR accompanied disease progression in both the R6/2 transgenic and HdhQ150 knockin mouse models of ...
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The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes
... the chromatin quasi-fibre and the aggregated loop/rosette 3D architecture of the human and mouse genomes: a Cell nuclei in a population of cells (transmission light and fluorescence microscopy, [89]) have ...
22
p63 cooperates with CTCF to modulate chromatin architecture in skin keratinocytes
... the chromatin structure is, however, not yet completely ...and chromatin accessibility, in skin keratinocytes isolated from EEC syndrome patients carrying p63 mutations, to examine the role of p63 in ...
13
Spatial chromatin architecture alteration by structural variations in human genomes at the population scale
... 3D chromatin structure including information on SVs and predicting enrichment/depletion of higher-order chromatin contacts caused by these variations ...
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Correction to: Spatial chromatin architecture alteration by structural variations in human genomes at the population scale
... d Models presenting 3D structure of the TAL1 locus without the deletion left column and with the deletion right column.. Schematic drawings of loops shown in c first row; 3D models with [r] ...
5
LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells
... in chromatin fragments between 150 and 300 bp in length (duty cycle 5%, intensity 4, cy- cles/burst 200; 40 cycles: 30 s on, 20 s off ...Sonicated chromatin was cleared by centrifugation for 10 min at 13000 ...
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Wippo, Christian (2011): In vitro reconstitution of the primary chromatin architecture of Saccharomyces cerevisiae. Dissertation, LMU München: Fakultät für Biologie
... Segal and Widom (2009) recently suggested an ‘equilibrium model for dynamic nucleosome positioning’, which assumes that nucleosomes equilibrate in vivo to their thermodynami- cally favoured positions as determined by the ...
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Albiez, Heiner (2007): Manipulation of global chromatin architecture in the human cell nucleus and critical assessment of current model views. Dissertation, LMU München: Fakultät für Biologie
... both chromatin modifications located in distances of only ±200 nm to the HCC bundle surface as expected for markers of ...active chromatin localized more towards the periphery than inactive chromatin ...
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Nuclear organization and 3D chromatin architecture in cognition and neuropsychiatric disorders
... looped chromatin in promoter-promoter interactions (the most common) or in the interactions between promoters and distal regulatory elements ...order chromatin structures in which RNAPII acts as a primary ...
12
Application of Texture Measures to Study Effect of B Chromosomes on the 3D Architecture of Plant Chromatin
... molecular chromatin structure are accompa- nied by recruitment of specific proteins and alteration of spatial (3D) chromatin architecture ...active chromatin regions ...
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Chromatin and Transcription in Yeast
... in chromatin architecture with enrichment of AT-rich sequences upstream of the mRP genes specifically in respiratory species, resulting in wide and deep NFRs in these species (Ihmels et ...
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THE EFFECT OF ADRIAMYCIN ON SALT FRACTIONATED CHROMATIN
... Serial concentrations of adriamycin was made in buffer and used as control. From this Figure it is evident thatthe binding pattern differs between fractions: Sl shows a pattern similar to the drug absorbance pattern but ...
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Chromatin in 3D: progress and prospects for plants
... observe chromatin in ...CRISPR/Cas-based chromatin-imaging method has already been used in mammalian cell lines for visualization of non-repetitive genomic loci ...
6
Identification of alternative topological domains in chromatin
... alternative chromatin domains exist and that a single length scale is insufficient to capture the hierarchi- cal and overlapping domain structure visible in heat maps of 3C interaction ...
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The conserved role of sirtuins in chromatin regulation
... Sirtuins have been phylogenetically divided into five types: I to IV, and U (Frye, 2000) (Fig. 1). Type I members are clearly linked to chromatin regulation—although not exclusively—and show true histone ...
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Chromatin and the cell cycle meet in Madrid
... Centromeres are not only marked by the deposition of CENH3, but also by extensive DNA methylation at repetitive elements and transposons (Lippman et al., 2005; Lister et al., 2008). Until now, the status of DNA ...
6
Poised chromatin in the mammalian germ line
... poised chromatin would help to resolve one of the central questions of germline biology: how do differentiated, apparently unipotent cells (the gametes) give rise to a totipotent zygote following fertilization? ...
8
Enterprise Architecture for Architecture Driven Planning
... As mentioned above, one of the goals of creating a modeling framework is to provide instant guidance to designers and to ensure conformance to your architecture principles. In fact, the ultimate goal should be to ...
22
Architecture, Enterprise Architecture, Frameworks, and Processes
... Enterprise architecture (in common use in industry) means the information systems that function as an organizational “nervous system,” enabling and facilitating the business processes that make the organization ...
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Koehler, Daniela (2009): Cloning in Cattle: Nuclear architecture and epigenetic status of chromatin during reprogramming of donor cell nuclei. Dissertation, LMU München: Fakultät für Biologie
... Besides all controversy concerning the existence of CT neighborhood pattern, there seems to be a consensus of a well defined radial distribution pattern (Croft et al. 1999; Bridger et al. 2000; Boyle et al. 2001; Cremer ...
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