chromatin structure
HSA: integrating multi track Hi C data for genome scale reconstruction of 3D chromatin structure
... (3D) chromatin conformation plays crucial roles in diverse genome functions, such as tran- scriptional regulation [1], DNA methylation [2], replica- tion [3] and cohesin binding ...3D chromatin conformation ...
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Trypanosoma brucei RRM1 Is a Nuclear RNA Binding Protein and Modulator of Chromatin Structure
... It has been shown that depletion of PTB2 causes major changes to the transcriptome, particularly mRNAs with C-rich splice sites (5). Since TbRRM1 and PTB2 interact, we attempted to compare the data sets. This was ...
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Drosophila Poly(ADP-Ribose) Glycohydrolase Mediates Chromatin Structure and SIR2-Dependent Silencing
... modulates chromatin structure, telomere elongation, DNA repair, and the transcription of genes involved in stress resistance, hormone responses, and ...promote chromatin silencing at least in part by ...
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Divergent Residues Within Histone H3 Dictate a Unique Chromatin Structure in Saccharomyces cerevisiae
... of chromatin structure with the assumption that, due to the high conservation of histones, data generated is relevant to other ...unique chromatin structure in ...
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Ectopic histone H3S10 phosphorylation causes chromatin structure remodeling in Drosophila
... maintaining chromatin structure and gene expression (Wang et ...of chromatin structure and that maintaining histone H3S10 phosphorylation levels at the euchromatic regions is necessary to ...
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Modulation of chromatin structure by the FACT histone chaperone complex regulates HIV 1 integration
... dense chromatin restricts the reaction and their remodeling can overcome this restriction [8, ...of chromatin and is closely linked to LEDGF/p75, we made the hypothesis that its remodeling activity could ...
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Chromatin Structure of the Simian Virus 40 Late Promoter: a Deletional Analysis
... local chromatin structure, particularly in pro- moter regions of activated genes, is a prerequisite for efficient transcription ...modulating chromatin remod- eling ...
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Linker histone epitopes are hidden by in situ higher-order chromatin structure
... situ chromatin higher- order structure, which is destroyed by the sonication step in ...higher-order chromatin structure at that particu- lar site, but does not explain what this ...
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Regulation of DNA transposition by CpG methylation and chromatin structure in human cells
... regions carry characteristic features, which distinguish them from euchromatic DNA, such as dense cytosine- methylation (5-Me-C) of CpG sites, hypo-acetylation of lysine residues in the N-terminal tails of histones H3 ...
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Remodeling of higher order chromatin structure by the JIL 1 histone H3 kinase in Drosophila
... silent chromatin interspersed with regions of decondensed, transcriptionally active chromatin (Khorasanizadeh, ...order chromatin structures (Ananiev and Barsky, 1985; Zhimulev et ...of ...
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Genome-Wide Chromatin Structure Changes During Adipogenesis and Myogenesis
... spatial chromatin structure requires more elaborate TADs to achieve more precise gene regulation and avoid disordered transcription during cell ...genome structure (from large nuclear compartments ...
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Methods for analyzing the role of DNA methylation and chromatin structure in regulating T lymphocyte gene expression
... of chromatin structure, such as histone acetylation and/or methylation, also contribute to the formation of the hypersensitive ...using chromatin immunoprecipitation approaches ...
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Kluyveromyces lactis Sir2p Regulates Cation Sensitivity and Maintains a Specialized Chromatin Structure at the Cryptic α-Locus
... ity compared to the wild-type strain. The Bcl I site found mitochondria, such as regulating a transport function. in the ␣3 open reading frame showed less than twofold We tested whether this potential transport defect ...
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Developmental Patterns of Chromatin Structure and DNA Methylation Responsible for Epigenetic Expression of a Maize Regulatory Gene
... methylation, chromatin structure, and developmental stage might contribute to the expression of Pl-Blotched, we used methylation-sensitive restriction enzymes and DNaseI sensitivity assays to compare the ...
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The Drosophila Boundary Element-Associated Factors BEAF-32A and BEAF-32B Affect Chromatin Structure
... of chromatin structure are not well understood, progressing from 30- nm fibers to looped ...of chromatin likely plays a functional role in this ...
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G9a/GLP-dependent H3K9me2 patterning alters chromatin structure at CpG islands in hematopoietic progenitors
... in chromatin accessibility for both groups in response to UNC0638 ...increases chromatin accessibility (Figure ...low chromatin accessibility regardless of methylation status, consistent with these ...
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Bayesian model based approaches in the analysis of chromatin structure and motif discovery
... of chromatin structure, consisting of DNA sequence wrapped around proteins called ...complex structure, in the form of dependence on neighboring probes as well as underlying DNA sequence, variable ...
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X chromosome activity: impact of imprinting and chromatin structure
... Int J D ,' Bioi 40 1065 1080 (1996) X chromosome activity impact of imprinting and chromatin structure ROBYN V JAMIESON PATRICK P L TAM' and MARGARET GARDINER GARDEN Embryology Unit Children's Medical[.] ...
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Glycolytic metabolism influences global chromatin structure
... condensed chromatin configuration, we wondered whether glycolytic metabolism might affect chromatin organization via modulation of histone ...regulated chromatin organization via modulation of ...
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Chromatin structure and DNA damage repair
... discussed chromatin remod- ellers provide sufficient space to allow these elongations, displaced nucleosomes need to be repositioned after ter- mination of these ...ATP-dependent chromatin remodellers are ...
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