chromosome 17
Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17)
... to chromosome 17 (FTDP-17) is an autosomal dominant neurodegenerative disorder, which has three cardinal features: behavioral and personality changes, cognitive impairment, and motor ...
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Polysomy of chromosome 17 in breast cancer tumors showing an overexpression of ERBB2: a study of 175 cases using fluorescence in situhybridization and immunohistochemistry
... There are different methods available to evaluate ERBB2 status [21], although immunohistochemistry (IHC; for pro- tein overexpression) and fluorescence in situ hybridization (FISH; for gene amplification) offer several ...
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Cytogenetic significance of chromosome 17 aberrations and P53 gene mutations as prognostic markers in oral squamous cell carcinoma
... This study revealed a statistical significant positive cor- relation between chromosome 17 abnormalities and the immunohistochemical expression of p53 proteins. Other previously reported findings suggest ...
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Interrelationship between TP53gene deletion, protein expression and chromosome 17 aneusomy in gastric adenocarcinoma
... 9, 17, 20, X and Y to be common in GC [[7,11-19], see also review ...at chromosome 17p13.1, and chromosome 17 (chr17) copy number alter- ations by FISH assay in GC [[21-24], see also review ...
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Screening of genetic loci predisposing to herpes simplex virus infection on mouse chromosome 17
... mouse chromosome 17 associated with susceptibility to HSV infection were then identified by correlation analysis and genome-wide scanning ...mouse chromosome, ...
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THE LOCUS ENCODING αA-CRYSTALLIN IS CLOSELY LINKED TO H-2K ON MOUSE CHROMOSOME 17
... To facili- tate studies of the genetics of lens crystallins and their involvement in heritable lens defects in mice, we have identified DNA restriction fragment length pol-[r] ...
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The proximal end of mouse chromosome 17: new molecular markers identify a deletion associated with quakingviable.
... In situ hybridization of 6.5 to 18.5 days post coitum embryos shows that message is present in all stages, but becomes confined mainly to the developing central nervo[r] ...
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THE INFLUENCE OF GENETIC BACKGROUND AND THE HOMOLOGOUS CHROMOSOME 17 ON t-HAPLOTYPE TRANSMISSION RATIO DISTORTION IN MICE
... We have provided unequivocal evidence in this paper that transmission ratio distortion of t-haplotypes is quite sensitive to the influence of its genetic environment, both t[r] ...
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A novel mouse chromosome 17 hybrid sterility locus: implications for the origin of t haplotypes.
... M. spretus-origin model of t haplotypes is that these chromosomes might not distort transmission ratios as drastically in a heterozygous combination with the M. spretus form [r] ...
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Normal testis determination in the mouse depends on genetic interaction of a locus on chromosome 17 and the Y chromosome.
... Finally, because ovarian tissue develops in gonads of XY, To"/+ mice if their Y chromosome is derived from the AKR/J inbred strain, whereas a C57BLIGJ-derived Y ch[r] ...
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SEVERAL GALACTOSYLTRANSFERASE ACTIVITIES ARE ASSOCIATED WITH MOUSE CHROMOSOME 17
... Because the galactosyltransferase assays were performed with UDP-Gal con- centrations that are very close to the typical K,,, values for these enzymes in other system[r] ...
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Functional analysis of mutations of murine chromosome 17 with the use of tertiary trisomy.
... was assigned to two groups: one obligatory, manifesting itself in the phenotype independently of the number of normal alleles in di- and trisomics, and the other facultative, [r] ...
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Cystic Dilation of the Aqueductus Sylvii in Case of Trisomy 17p11.2—pter with the Deletion of the Terminal Portion of the Chromosome 6
... The phenotypical manifestation depends on the chro- mosomal breakpoints. The expected phenotypic features of trisomy 17p are microcephaly, mandibular hypoplasia, antimongoloid slanting of palpebral fissures, a ...
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Telomere shortening and telomere position effect in mild ring 17 syndrome
... ring 17 (2%). Chromosome analysis of the patient ’ s parents displayed a normal paternal karyotype, and a mosaic ring 17 ma- ternal karyotype: ...normal chromosome 17 and on the ...some ...
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Prenatal Diagnosis of 17p13.1p13.3 Duplication
... Prenatal chromosome analysis (G-banding) performed on cultured amniocytes (in situ and long term) indicated the presence of additional material in chromosome 19 of the ...whole chromosome 19 painting ...
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CHARACTERIZATION OF A RECOMBINANT MOUSE t HAPLOTYPE THAT EXPRESSES A DOMINANT LETHAL MATERNAL EFFECT
... We report here the discovery of another mutant form of mouse chromosome 17 that expresses a maternal effect very similar to that associated with the ThP deletion.. This novel[r] ...
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Overexpressions of Cyclin B1, cdc2, p16 and p53 in Human Breast Cancer: The Clinicopathologic Correlations and Prognostic Implications
... p16 regulation is an essential step in the pathway that links mitogenic signals to cell cycle progression.17 The p53 gene is located on the short arm of chromosome 17, and alterations in[r] ...
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TRAITS THAT INFLUENCE LONGEVITY IN MICE
... T h e coat color (b locus) segment of chromosome 4 was associated with life span predominantly in females, whereas the chromosome 17 (H-2 haplotype) segment was assoc[r] ...
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Generation of a Mouse Full-length Balancer with Versatile Cassette-shuttling Selection Strategy
... on chromosome 17 were also verified by PCR on all four inversion points ...17M-GFP chromosome was established in 129S1/SvImJ ...17M-GFP chromosome can be easily detected from early embryonic ...
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Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells
... Studies were approved by Mayo Clinic under IRB proto- cols (09-003803 and 12-002562). Clinically affected two patients from PPND family were recruited; #1) 48 year-old patient (male, Caucasian) with the disease onset at ...
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