Chromosome 17 (human)
Interrelationship between TP53gene deletion, protein expression and chromosome 17 aneusomy in gastric adenocarcinoma
... 9, 17, 20, X and Y to be common in GC [[7,11-19], see also review ...at chromosome 17p13.1, and chromosome 17 (chr17) copy number alter- ations by FISH assay in GC [[21-24], see also review ...
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Screening of genetic loci predisposing to herpes simplex virus infection on mouse chromosome 17
... mouse chromosome 17 associated with susceptibility to HSV infection were then identified by correlation analysis and genome-wide scanning ...mouse chromosome, ...
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Cytogenetic significance of chromosome 17 aberrations and P53 gene mutations as prognostic markers in oral squamous cell carcinoma
... of chromosome 17 abnormalities has been reported in some human cancers such as breast car- cinoma, colon carcinoma and bladder carcinoma ...of chromosome 17 are significantly increased in ...
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Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17)
... to chromosome 17 (FTDP-17) is an autosomal dominant neurodegenerative disorder, which has three cardinal features: behavioral and personality changes, cognitive impairment, and motor ...
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Polysomy of chromosome 17 in breast cancer tumors showing an overexpression of ERBB2: a study of 175 cases using fluorescence in situhybridization and immunohistochemistry
... of chromosome 17 (13%), and three cases presented monosomy (2%) (Table ...of chromosome 17 copy numbers in this 2+/3+ subgroup is illustrated in ...polysomy 17 had four copies of ...
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Overexpressions of Cyclin B1, cdc2, p16 and p53 in Human Breast Cancer: The Clinicopathologic Correlations and Prognostic Implications
... p16 regulation is an essential step in the pathway that links mitogenic signals to cell cycle progression.17 The p53 gene is located on the short arm of chromosome 17, and alterations in[r] ...
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Normal testis determination in the mouse depends on genetic interaction of a locus on chromosome 17 and the Y chromosome.
... Finally, because ovarian tissue develops in gonads of XY, To"/+ mice if their Y chromosome is derived from the AKR/J inbred strain, whereas a C57BLIGJ-derived Y ch[r] ...
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Evaluation of 7q31 region improves the accuracy of EGFR FISH assay in non small cell lung cancer
... not chromosome 17 polysomy seems to confer sensi- tivity to monoclonal antibody trastuzumab [34,35], it has been reported that patients with NSCLC can derive a clin- ical benefit from TKIs therapy when EGFR ...
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THE INFLUENCE OF GENETIC BACKGROUND AND THE HOMOLOGOUS CHROMOSOME 17 ON t-HAPLOTYPE TRANSMISSION RATIO DISTORTION IN MICE
... We have provided unequivocal evidence in this paper that transmission ratio distortion of t-haplotypes is quite sensitive to the influence of its genetic environment, both t[r] ...
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The proximal end of mouse chromosome 17: new molecular markers identify a deletion associated with quakingviable.
... In situ hybridization of 6.5 to 18.5 days post coitum embryos shows that message is present in all stages, but becomes confined mainly to the developing central nervo[r] ...
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SEVERAL GALACTOSYLTRANSFERASE ACTIVITIES ARE ASSOCIATED WITH MOUSE CHROMOSOME 17
... Because the galactosyltransferase assays were performed with UDP-Gal con- centrations that are very close to the typical K,,, values for these enzymes in other system[r] ...
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THE LOCUS ENCODING αA-CRYSTALLIN IS CLOSELY LINKED TO H-2K ON MOUSE CHROMOSOME 17
... To facili- tate studies of the genetics of lens crystallins and their involvement in heritable lens defects in mice, we have identified DNA restriction fragment length pol-[r] ...
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A novel mouse chromosome 17 hybrid sterility locus: implications for the origin of t haplotypes.
... M. spretus-origin model of t haplotypes is that these chromosomes might not distort transmission ratios as drastically in a heterozygous combination with the M. spretus form [r] ...
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ETHYLNITROSOUREA MUTAGENESIS AND THE ISOLATION OF MUTANT ALLELES FOR SPECIFIC GENES LOCATED IN THE t REGION OF MOUSE CHROMOSOME 17
... One mutagen- ized male gave two quaking progeny (qk' and qkk2). Table 5 presents data from these males demonstrating the heritability, recessive phenotype and probable l[r] ...
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Functional analysis of mutations of murine chromosome 17 with the use of tertiary trisomy.
... was assigned to two groups: one obligatory, manifesting itself in the phenotype independently of the number of normal alleles in di- and trisomics, and the other facultative, [r] ...
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Genome scan study of prostate cancer in Arabs: identification of three genomic regions with multiple prostate cancer susceptibility loci in Tunisians
... on chromosome 17 are associated with the expression of STAT5B gene, which encodes a signal transducer and activator of transcription 5B, and the risk alleles were consistently associated with increased ...
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Cystic Dilation of the Aqueductus Sylvii in Case of Trisomy 17p11.2—pter with the Deletion of the Terminal Portion of the Chromosome 6
... study involved chromosome 17. One of these cases, the nuchal translucency thickness was 3.1 mm, but in the other it was only 1.3 mm [15]. There is no doubt that first trimester ultrasound examination has a ...
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CHARACTERIZATION OF A RECOMBINANT MOUSE t HAPLOTYPE THAT EXPRESSES A DOMINANT LETHAL MATERNAL EFFECT
... We report here the discovery of another mutant form of mouse chromosome 17 that expresses a maternal effect very similar to that associated with the ThP deletion.. This novel[r] ...
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Generation of a Mouse Full-length Balancer with Versatile Cassette-shuttling Selection Strategy
... on chromosome 17 were also verified by PCR on all four inversion points ...17M-GFP chromosome was established in 129S1/SvImJ ...17M-GFP chromosome can be easily detected from early embryonic ...
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Telomere shortening and telomere position effect in mild ring 17 syndrome
... rearranged chromosome is preferen- tially lost during cell divisions, leading to apoptosis and premature cell ...ring chromosome and the occur- rence of this peculiar ...ring chromosome 17 ...
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