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Chronic allograft nephropathy

Expression of vascular endothelial growth factor in the early stage of rats’ kidney with Chronic Allograft Nephropathy

Expression of vascular endothelial growth factor in the early stage of rats’ kidney with Chronic Allograft Nephropathy

... It is shown that the previous studies of chronic allograft nephropathy (CAN) rat models(Zununi Vahed et al. 2016, Xue et al. 2016, Zhou et al. 2015, Shrestha and Haylor 2014, Li and Zhuang 2014, Han ...

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Experimental rat models of chronic allograft nephropathy: a review

Experimental rat models of chronic allograft nephropathy: a review

... Abstract: Chronic allograft nephropathy (CAN) is the leading cause of late allograft loss after renal transplantation (RT), which continues to remain an unresolved ...

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Original Article Application value of shear wave elastography technique in diagnosis of chronic allograft nephropathy

Original Article Application value of shear wave elastography technique in diagnosis of chronic allograft nephropathy

... that chronic allograft nephropathy (CAN) is the main cause to long-term graft function [2], and what’s more, after excluding acute rejection and the clear causes that lead to chronic renal ...

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Dramatic early event in chronic allograft nephropathy: increased but not decreased expression of MMP-9 gene

Dramatic early event in chronic allograft nephropathy: increased but not decreased expression of MMP-9 gene

... It was shown in our data that MMP-9 expression was upregulated in the early stage of CAN, at the same time there was significant mononuclear cells infiltration in the interstitium of allografts, and the MMP-9 expression ...

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Mycophenolate mofetil and FK506 have different effects on kidney allograft fibrosis in rats that underwent chronic allograft nephropathy

Mycophenolate mofetil and FK506 have different effects on kidney allograft fibrosis in rats that underwent chronic allograft nephropathy

... day. Allograft surgery which meets the fol- lowing two criteria was considered as valid: (1) When vascular anastomosis is completed, the transplant kidneys immediately become red after circulation returns, with a ...

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“BK Polyomavirus (BKV) Infection and Nephropathy in Renal Transplant Recipients: A Prospective Study at Tertiary Care Center” by Sushma Singh, Narayan Prasad, Monisha banerjee, Dharam Veer Singh, Swati Saxena, Jyoti Umrao, Dr.Tapan N.Dhole, India.

“BK Polyomavirus (BKV) Infection and Nephropathy in Renal Transplant Recipients: A Prospective Study at Tertiary Care Center” by Sushma Singh, Narayan Prasad, Monisha banerjee, Dharam Veer Singh, Swati Saxena, Jyoti Umrao, Dr.Tapan N.Dhole, India.

... males (n=125) and 16.6% (n=25) of females. Ninety eight percent (147/150) were recipients from living donors and three were recipients from deceased donors. Out of these 98% living donor transplants, 52 % (n=78) donors ...

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Inhibition of NK cell-mediated Cytotoxicity by Tubular Epithelial Cell Expression of Clr Proteins

Inhibition of NK cell-mediated Cytotoxicity by Tubular Epithelial Cell Expression of Clr Proteins

... acute allograft rejection have been reduced by the application of potent immunosuppressive ...drugs, chronic allograft dysfunction remains the leading cause of late kidney graft loss ...(58). ...

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Renal Structural Changes after Kidney Allograft Transplantation

Renal Structural Changes after Kidney Allograft Transplantation

... in allograft function is observed in about 40 to 50% of the patients who receive a kidney allograft transplant at two or more years after ...diabetic nephropathy. More frequently less specifi c ...

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Expression of GSK-3β in renal allograft tissue and its significance in pathogenesis of chronic allograft dysfunction

Expression of GSK-3β in renal allograft tissue and its significance in pathogenesis of chronic allograft dysfunction

... Recent researches have found that the GSK-3b family of serine/threonine kinases extensively existed in the eucaryon, and mainly express in the lung, kidney and brain, and influence on construction, growth, activation and ...

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CYP3A5 polymorphisms in renal transplant recipients: influence on tacrolimus treatment

CYP3A5 polymorphisms in renal transplant recipients: influence on tacrolimus treatment

... CYP3A5 *1 allele associated with tacrolimus trough concentrations but not subclinical acute rejection or chronic allograft nephropathy in Japanese renal transplant recipients. Hesselin[r] ...

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Hyperuricemia in Patients with Chronic Renal Failure in the General Hospital of National Reference of N’Djamena (Chad)

Hyperuricemia in Patients with Chronic Renal Failure in the General Hospital of National Reference of N’Djamena (Chad)

... of chronic kidney ...with chronic kidney disease (CKD), arterial hypertension and cardiovascular diseases, thus raising the question of the usefulness of therapeutics in the prevention of renal ...between ...

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Surveillance Renal Allograft Biopsy on Diagnosis of BK Virus Nephropathy in Chinese Renal Transplant Recipients

Surveillance Renal Allograft Biopsy on Diagnosis of BK Virus Nephropathy in Chinese Renal Transplant Recipients

... [7,8]. Celik et al. took the initiative in regular biopsy after renal transplantation, which contributed to timely diagnosis of BKVAN [9]. Currently, there are transplant centers which have begun to carry out some ...

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Nephron supply is a major determinant of long term renal allograft outcome in rats

Nephron supply is a major determinant of long term renal allograft outcome in rats

... observed allograft protection derived from the presence of a retained recipient native kidney supports the hypothesis that a single renal allograft contains insufficient nephrons to ...

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Retracted: C4d deposition in native kidney disease and its correlation with proteinuria and serum urea/creatinine

Retracted: C4d deposition in native kidney disease and its correlation with proteinuria and serum urea/creatinine

... al, on 15 patients of native idiopathic membranous nephropathy, 10 out of 15 kidney biopsies (66.6%) showed glomerular capillary wall deposition of C4d (8). A study conducted by Min-Kyung Kim et al, found that out ...

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Assessment of the Siksika chronic disease nephropathy-prevention clinic

Assessment of the Siksika chronic disease nephropathy-prevention clinic

... was extended to 13.3 years, a trend to lower cardio- vascular deaths and a 20% absolute risk reduction in death emerged among the intensively treated individ- uals. Additionally, intensive control lowered diabetic ...

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Functional and histological improvement after everolimus rescue of chronic allograft dysfunction in renal transplant recipients

Functional and histological improvement after everolimus rescue of chronic allograft dysfunction in renal transplant recipients

... rather than empiric conversion and calcineurin inhibitor minimization, could have offered opportunities to show the benefit of mTOR inhibitors. An “entry passport” as obtained from graft biopsy before mTOR inhibitor ...

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Etiology and determinants of allograft dysfunction.

Etiology and determinants of allograft dysfunction.

... A variety of drugs can cause acute dysfunction of the renal allograft. In many cases, the offending agent are aminoglycoside , amphotericin, NSAID, ACE or ARBs in the presence of transplant renal artey stenosis, ...

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Nutritional supplementation to prevent and slow the progression of chronic kidney disease: focus on bicarbonate

Nutritional supplementation to prevent and slow the progression of chronic kidney disease: focus on bicarbonate

... with chronic kidney disease, metabolic acidosis has been linked to disorders of muscle and bone ...induced nephropathy has generated considerable ...induced nephropathy is a common complication of ...

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B cells mediate chronic allograft rejection independently of antibody production

B cells mediate chronic allograft rejection independently of antibody production

... late allograft failure remains a clinical challenge despite advances in immunosuppression ...of chronic rejection is concentric intimal hyper- plasia, termed chronic allograft vasculopathy ...

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Contrast-Induced Nephropathy Among Patients Undergoing Cardiac Catheterization

Contrast-Induced Nephropathy Among Patients Undergoing Cardiac Catheterization

... Contrast-induced nephropathy (CIN) is defined as an absolute (≥ 0.5mg/dL) or relative increase (≥ 25%) in serum creatinine at 48–72h after exposure to a contrast agent compared to baseline serum creatinine level, ...

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