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Chronic Constriction Injury

AMELIORATIVE EFFECTS OF MURRAYA KOENIGII IN CHRONIC CONSTRICTION INJURY OF SCIATIC NERVE INDUCED NEUROPATHIC PAIN IN RATS

AMELIORATIVE EFFECTS OF MURRAYA KOENIGII IN CHRONIC CONSTRICTION INJURY OF SCIATIC NERVE INDUCED NEUROPATHIC PAIN IN RATS

... by chronic constriction injury of sciatic nerve in ...a chronic condition which is characterized by the sensory symptoms like hyperalgesia and ...nerve injury produces robust thermal ...

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A bacosides containing Bacopa monnieri extract alleviates allodynia and hyperalgesia in the chronic constriction injury model of neuropathic pain in rats

A bacosides containing Bacopa monnieri extract alleviates allodynia and hyperalgesia in the chronic constriction injury model of neuropathic pain in rats

... the chronic constriction injury model of neuro- pathic pain under standardized experimental ...nerve injury combined with testing of pain hypersensitivity are useful in representing human ...

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Original Article Involvement of spinal SIRT1 in development of chronic constriction injury induced neuropathic pain in rats

Original Article Involvement of spinal SIRT1 in development of chronic constriction injury induced neuropathic pain in rats

... and hyperalgesia in neuropathic pain. The neuropathic pain model was established by ligature of the right sciatic nerve to induce chronic constriction injury (CCI) in rats. Histone acetyltransferase ...

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Attenuating effect of Acorus calamus extract in chronic constriction injury induced neuropathic pain in rats: an evidence of anti oxidative, anti inflammatory, neuroprotective and calcium inhibitory effects

Attenuating effect of Acorus calamus extract in chronic constriction injury induced neuropathic pain in rats: an evidence of anti oxidative, anti inflammatory, neuroprotective and calcium inhibitory effects

... inflammation, chronic constriction injury and axotomy of sciatic nerve and ischemia-reperfusion of femoral artery mediated neuropathic pain ...

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Ameliorative potential of Alstonia scholaris (Linn ) R  Br  against chronic constriction injury induced neuropathic pain in rats

Ameliorative potential of Alstonia scholaris (Linn ) R Br against chronic constriction injury induced neuropathic pain in rats

... Methods: Peripheral neuropathy was induced by chronic constriction injury of sciatic nerve. The behavioral parameters like mechanical and thermal hyperalgesia and cold allodynia were assessed on the ...

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Intraperitoneally Administered Lidocaine Attenuates Thermal Allodynia in a Murine “Two Hit” Chronic Constriction Injury Model

Intraperitoneally Administered Lidocaine Attenuates Thermal Allodynia in a Murine “Two Hit” Chronic Constriction Injury Model

... of chronic pain ...of injury cause a reduction in fir- ing threshold of afferent nerve endings, ...and chronic hyperalgesia and allodynia which results from ongoing input in the central nervous ...

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Original Article Downregulation of miR-206 contributes to neuropathic pain in rats by enhancing RASA1 expression

Original Article Downregulation of miR-206 contributes to neuropathic pain in rats by enhancing RASA1 expression

... (NP), chronic pain resulted from dysfunction or diseases of the somatosensory nervous system, is a major challenge to currently available clinical therapy of peripheral nerve ...and chronic ...

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Original Article Overexpression of miR-30a attenuates neuropathic pain by targeting SOCS1 in rats with chronic constriction injury

Original Article Overexpression of miR-30a attenuates neuropathic pain by targeting SOCS1 in rats with chronic constriction injury

... Abstract: Objectives: To explore the impact of miR-30a on neuropathic pain and associated mechanism. Methods: Sprague-Dawley (SD) rats were randomly assigned to bilateral chronic constriction injury ...

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Original Article Expression of 18 KDa translocator protein by microglia in spinal cord and hippocampus in rats with neuropathic pain

Original Article Expression of 18 KDa translocator protein by microglia in spinal cord and hippocampus in rats with neuropathic pain

... a chronic constriction injury of the sciatica nerve in a rat model, this study explores the possible mechanism between TSPO expres- sion and cognitive ...

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Activation of hippocampal MEK1 contributes to the cumulative antinociceptive effect of electroacupuncture in neuropathic pain rats

Activation of hippocampal MEK1 contributes to the cumulative antinociceptive effect of electroacupuncture in neuropathic pain rats

... in chronic constriction injury (CCI)-induced neuropathic pain rats, the cumulative analgesic effect of repeated EA stimulation of Zusanli (ST36)-Yanglingquan (GB34) is closely associated with its ...

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Original Article Paeoniflorin attenuates neuropathic pain through the regulation of Sirt1 in rats

Original Article Paeoniflorin attenuates neuropathic pain through the regulation of Sirt1 in rats

... neuronal injury, although the underlying mechanism remains ...with chronic constriction ...with chronic constriction injury (CCI) than in the sham group ...

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Vangl2 cooperates with Rab11 and Myosin V to regulate apical constriction during vertebrate gastrulation

Vangl2 cooperates with Rab11 and Myosin V to regulate apical constriction during vertebrate gastrulation

... Given that Rab11 is required for blastopore formation and that its apical enrichment depends on Vangl2, we hypothesized that Vangl2 controls apical constriction by modulating Rab11 localization and function. We ...

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Effects of neurally adjusted ventilatory assist on air distribution and dead space in patients with acute exacerbation of chronic obstructive pulmonary disease

Effects of neurally adjusted ventilatory assist on air distribution and dead space in patients with acute exacerbation of chronic obstructive pulmonary disease

... of chronic obstructive pulmonary disease (AECOPD) is a disease state characterized by expiratory airflow limitation, increasing dead space, and diaphragm dysfunction [1], and invasive mechanical venti- lation (MV) ...

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Vascular endothelial cadherin shedding is more severe in sepsis patients with severe acute kidney injury

Vascular endothelial cadherin shedding is more severe in sepsis patients with severe acute kidney injury

... Sepsis commonly leads to organ dysfunction or failure, with AKI being one of the most common sepsis-related organ dysfunctions. Decreased renal blood flow in sepsis results in endothelial activation and increased renal ...

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βIV Spectrin regulates STAT3 targeting to tune cardiac response to pressure overload

βIV Spectrin regulates STAT3 targeting to tune cardiac response to pressure overload

... cycling proteins, and mitochondrial proteins) cannot be ruled out (3, 9, 45, 46). Together, these data suggest that the β IV -spectrin C-terminal domain (CTD) serves as a “pathological” membrane dock for intracellular ...

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Pupil light reflex evoked by light emitting diode and computer screen: methodology and association with need for recovery in daily life

Pupil light reflex evoked by light emitting diode and computer screen: methodology and association with need for recovery in daily life

... RCA, constriction velocity, redila- tion velocity and one-third-redilation recovery time) were tested over a time window of 10 minutes and again after one ...in constriction velocity between these two ses- ...

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Timing of renal replacement therapy initiation by AKIN classification system

Timing of renal replacement therapy initiation by AKIN classification system

... Kidney Injury Network; APACHE II: Acute Physiology and Chronic Health Evaluation II; CKD: chronic kidney disease; CKD-EPI: chronic kidney disease epidemiology collaboration; ED: early ...

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High urinary excretion of kidney injury molecule 1 predicts adverse outcomes in acute kidney injury: a case control study

High urinary excretion of kidney injury molecule 1 predicts adverse outcomes in acute kidney injury: a case control study

... The incidence rate of AKI is high, and is showing a trend of annual increase. AKI is common in hospitalized patients, especially critical patients; critical patients with AKI have high mortality rates. Recent ...

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Chronic coronary artery constriction leads to moderate myocyte loss and left ventricular dysfunction and failure in rats

Chronic coronary artery constriction leads to moderate myocyte loss and left ventricular dysfunction and failure in rats

... Coronary artery narrowing, ranging from 19% to 61%, was induced in rats and ventricular performance, myocardial damage, and myocyte hypertrophy were examined 1 mo later. Animals were separated into two groups, exhibiting ...

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Continuous venovenous hemofiltration in severely burned patients with acute kidney injury: a cohort study

Continuous venovenous hemofiltration in severely burned patients with acute kidney injury: a cohort study

... inhalation injury (n = 1), preexisting chronic renal insufficiency (n = 4), percentage TBSA less than 40% (n = 1), and non-thermal injury (n = ...preexisting chronic renal insufficiency (n = ...

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