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Chronic HCV Infection

PD 1 tempers Tregs in chronic HCV infection

PD 1 tempers Tregs in chronic HCV infection

... during chronic HCV infection by demonstrating that Treg proliferation is inhibited by PD-1 and that this inhibition is mediated by a potentially novel mechanism involving the prevention of ...

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DISTRIBUTION PATTERN OF HCV GENOTYPES AND SUBGENOTYPES AND THEIR ASSOCIATION WITH VIRAL LOAD IN A GROUP OF IRAQI PATIENTS WITH CHRONIC HCV INFECTION

DISTRIBUTION PATTERN OF HCV GENOTYPES AND SUBGENOTYPES AND THEIR ASSOCIATION WITH VIRAL LOAD IN A GROUP OF IRAQI PATIENTS WITH CHRONIC HCV INFECTION

... of HCV sub-genotypes in ...of HCV sub genotypes among a group of Iraqi patients with chronic HCV ..."Versant-LiPA HCV Genotyping ...of HCV sub-genotypes 1a was higher in male ...

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Arbidol: a broad spectrum antiviral that inhibits acute and chronic HCV infection

Arbidol: a broad spectrum antiviral that inhibits acute and chronic HCV infection

... mary infection, and over several weeks of treatment in persistent HCV infection, might indicate a prerequisite for ARB accumulation in intracellular compartments before antiviral activity is ...

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Soluble egg antigen of Schistosoma Haematobiuminduces HCV replication in PBMC from patients with chronic HCV infection

Soluble egg antigen of Schistosoma Haematobiuminduces HCV replication in PBMC from patients with chronic HCV infection

... Fifteen ml of blood were withdrawn from each patient [approved by the medical ethical committee of (NRC)], five of them were collected on EDTA and were used to extract total cellular RNA from PBMC (to assess the pres- ...

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Serum syndecan 1 and apolipoprotein a1 in patients with chronic hcv infection

Serum syndecan 1 and apolipoprotein a1 in patients with chronic hcv infection

... liver disease, serum Apo A-I increases in patients with normal liver, steatosis, and decreases in liver fibrosis and cirrhosis (Poynard et al., 1987). Recently, Kim et al., 2010 reported that ApoA-1 is expressed in the ...

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Suggested guidelines for the diagnosis and management of chronic HCV infection in children

Suggested guidelines for the diagnosis and management of chronic HCV infection in children

... sensitive HCV RNA assay for definite con- firmation is the usual diagnostic protocol ...of HCV-RNA in both the mother and the infant is the most reliable indicator of vertical transmission of HCV ...

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Hepatitis C virus (HCV) core serotypes in chronic HCV infection

Hepatitis C virus (HCV) core serotypes in chronic HCV infection

... Comparative evaluation of HCV core region serotyping and genotyping with sera from 294 viremic patients infected with a known HCV genotype showed a remarkable concordance between HCV cor[r] ...

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Chronic HCV infection: epidemiological and clinical relevance

Chronic HCV infection: epidemiological and clinical relevance

... and chronic hepatitis in 1989, plays a major role as a cause of chronic liver injury, with potential for neoplastic ...of infection occurred in the 1945-65 period (baby boomers) in western ...acute ...

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The Association Between Systemic Hypertension and Chronic HCV-4 Infection

The Association Between Systemic Hypertension and Chronic HCV-4 Infection

... with chronic hepatitis C virus infection are more likely to have systemic hypertension, in addition to insulin resistance and ...and chronic HCV-4 infection among Egyptian ...with ...

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Hepatitis C Virus (HCV)-Related Cryoglobulinemia: Cryoglobulin Type and Anti-HCV Profile

Hepatitis C Virus (HCV)-Related Cryoglobulinemia: Cryoglobulin Type and Anti-HCV Profile

... of chronic HCV infection and is associated with several clinical and labora- tory autoimmune events (4, ...of HCV cryo- globulinemia largely varies from an asymptomatic presentation to severe ...

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Evolution of the Hepatitis C Virus Second Envelope Protein Hypervariable Region in Chronically Infected Patients Receiving Alpha Interferon Therapy

Evolution of the Hepatitis C Virus Second Envelope Protein Hypervariable Region in Chronically Infected Patients Receiving Alpha Interferon Therapy

... with chronic HCV infection treated with alpha interferon (IFN- ␣ ) at the approved dose of 3 MU three times a week for 6 months and in about 25% of those receiving this treatment for 12 ...of ...

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EPIDEMIOLOGY OF HEPATOCELLULAR CARCINOMA

EPIDEMIOLOGY OF HEPATOCELLULAR CARCINOMA

... Europe has a slightly higher incidence (2-4 times) of HCC than the United States. The Mediterranean countries (Italy, Spain, and Greece) have incidence rates ranging from 10-20 per 100,000 individuals. These countries ...

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Hepatitis C Patient-Derived Glycoproteins Exhibit Marked Differences in Susceptibility to Serum Neutralizing Antibodies: Genetic Subtype Defines Antigenic but Not Neutralization Serotype

Hepatitis C Patient-Derived Glycoproteins Exhibit Marked Differences in Susceptibility to Serum Neutralizing Antibodies: Genetic Subtype Defines Antigenic but Not Neutralization Serotype

... The observed disparity in the neutralization sensitivity of E1E2 proteins is an important issue. It has been reported previously that heterologous neutralizing antibodies are fre- quently isolated in chronic ...

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Clinical Implications of Chemokines in Acute and Chronic Hepatitis C Virus Infection

Clinical Implications of Chemokines in Acute and Chronic Hepatitis C Virus Infection

... of HCV infection. In chronic HCV infection, on the contrary, HCV replicates persistently within the hepato- cytes, thus sustaining chemokine ...liver-infiltrating ...

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Assessment of human cytomegalovirus co infection in Egyptian chronic HCV patients

Assessment of human cytomegalovirus co infection in Egyptian chronic HCV patients

... recurrent infection can occur [18]. The diagnosis of active CMV infection was based on the detection of CMV replication in the ...HCMV infection in Egyptian HCV patients who either ...

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Association of IFNL3 rs12979860 polymorphism with HCV-related hepatocellular carcinoma susceptibility in a Chinese population

<p>Association of <em>IFNL3</em> rs12979860 polymorphism with HCV-related hepatocellular carcinoma susceptibility in a Chinese population</p>

... with chronic HCV infection were enrolled, including 62 HCV-related HCC patients and 95 chronic hepatitis C (CHC) patients without HCC, and the genetic polymorphism of IFNL3 rs12979860 ...

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Enhanced Expression of Interferon-Regulated Genes in the Liver of Patients with Chronic Hepatitis C Virus Infection: Detection by Suppression-Subtractive Hybridization

Enhanced Expression of Interferon-Regulated Genes in the Liver of Patients with Chronic Hepatitis C Virus Infection: Detection by Suppression-Subtractive Hybridization

... (HCV) infection causes acute and often also chronic liver ...of infection is estimated to exceed that of human immunodeficiency virus infection ...in HCV-infected and ...

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Hepatitis C virus replicative levels and efficiency of genotyping by specific PCR and antibody assay

Hepatitis C virus replicative levels and efficiency of genotyping by specific PCR and antibody assay

... with chronic HCV infection who were positive for HCV RNA in serum according to the results of PCR were ...for HCV RNA in their serum, had chronic HCV infection, and ...

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Role of FoxP3+T Regulatory Cells in Chronic HCV and Its Relation to Disease Severity

Role of FoxP3+T Regulatory Cells in Chronic HCV and Its Relation to Disease Severity

... in chronic HCV infection by investigating its correlation with HCV load by PCR and its relation to the liver structural injury scored by the grades of activity and stages of ...compensated ...

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Decreased hepatocellular carcinoma tumor burden with the achievement of hepatitis C virus sustained virologic response: unlocking the potential of T-cell-mediated immunosurveillance

Decreased hepatocellular carcinoma tumor burden with the achievement of hepatitis C virus sustained virologic response: unlocking the potential of T-cell-mediated immunosurveillance

... of chronic hepatitis C virus (HCV) infection, and now a cure, as defined by undetectable HCV RNA in the blood 12 weeks after treatment ends (sustained virologic response [SVR]), can be ...

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